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  • T6295Dabigatran达比加群;BIBR 953;BIBR 953ZW

    Dabigatran is a THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk of stroke and systemic EMBOLISM in patients with nonvalvular atrial fibrillation.

    价 格:¥电议型 号:T6295产 地:中国大陆

  • T6294NVP-BSK805 2HCl (1092499-93-8(free base))BSK 805

    NVP-BSK805 2HCl(IC50=0.5 nM), a specific and effective ATP-competitive JAK2 inhibitor, is more than 20-fold specificity over JAK1, JAK3 and TYK2.

    价 格:¥电议型 号:T6294产 地:中国大陆

  • T6293Mycophenolate MofetilTM-MMF;RS 61443;吗替麦考酚酯

    Mycophenolate mofetil, an immunosuppressive agent, is the 2-morpholinoethyl ester of mycophenolic acid (MPA), and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).

    价 格:¥电议型 号:T6293产 地:中国大陆

  • T6291WZ4003

    WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively. It is no significant inhibition on 139 other kinases.

    价 格:¥电议型 号:T6291产 地:中国大陆

  • T6290TanespimycinKOS 953;17-AAG;CP 127374;NSC 330507;坦螺旋霉素

    Tanespimycin (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell Hsp90 (IC50: 5 nM).

    价 格:¥电议型 号:T6290产 地:中国大陆

  • T6289DovitinibCHIR-258;TKI258;多韦替尼;度维替尼

    Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 nM), also effective to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs (IC50: 8-13 nM), less potent to EGFR, InsR, EphA2, c-Met, IGF-1R, Tie2, and HER

    价 格:¥电议型 号:T6289产 地:中国大陆

  • T6287TariquidarXR9576;他立喹达

    Tariquidar(Kd=5.1 nM) is a specific and effective non-competitive inhibitor of P-glycoprotein. It can reverse drug resistance in MDR cell Lines.

    价 格:¥电议型 号:T6287产 地:中国大陆

  • T6285GSK-690693GSK690693

    GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.

    价 格:¥电议型 号:T6285产 地:中国大陆

  • T6284OnalespibAT13387;Onalespib (AT13387)

    Onalespib is a synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Onalespib selectively binds to Hsp90, thereby inhibiting its chaperone function and promoting the degradation

    价 格:¥电议型 号:T6284产 地:中国大陆

  • T6283Wortmannin渥曼青霉素;KY-12420;SL-2052

    Wortmannin is the first described PI3K inhibitor with IC50 of 3 nM, with little selectivity within the PI3K family. Also blocks autophagosome formation and potently inhibits DNA-PK/ATM with IC50 of 16 nM and 150 nM.

    价 格:¥电议型 号:T6283产 地:中国大陆

  • T6282GSK461364GSK461364A

    GSK461364(Ki=2.2 nM) inhibits purified Plk1 .The specificity of GSK461364 for Plk1 is more than 1000-fold over Plk2/3.

    价 格:¥电议型 号:T6282产 地:中国大陆

  • T6281TW-37TW37;TW 37

    TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM).

    价 格:¥电议型 号:T6281产 地:中国大陆

  • T6280EnzastaurinLY317615;恩扎妥林

    Enzastaurin (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.

    价 格:¥电议型 号:T6280产 地:中国大陆

  • T6279LGivinostat hydrochlorideITF 2357;Givinostat HCl. gavinostat,;Givinostat HCl;ITF2357 HCl;ITF2357 hydr

    Givinostat hydrochloride is an inhibitor of HDAC with IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat hydrochloride exhibits anti-inflammatory, anti-angiogenic, and antineoplastic activities.

    价 格:¥电议型 号:T6279L产 地:中国大陆

  • T6279Givinostat hydrochloride monohydrate吉维司他;Givinostat;ITF-2357 hydrochloride monohydrate;ITF2357;Gavin

    Givinostat hydrochloride monohydrate is an HDAC inhibitor.

    价 格:¥电议型 号:T6279产 地:中国大陆

  • T6278SotrastaurinAEB071;索曲妥林

    Sotrastaurin is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).

    价 格:¥电议型 号:T6278产 地:中国大陆

  • T6277DoramapimodBIRB 796;达马莫德;度马莫德

    Doramapimod is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.

    价 格:¥电议型 号:T6277产 地:中国大陆

  • T6276KU-57788NU7441

    NU7441 (KU-57788) is a highly effective and specific DNA-PK inhibitor (IC50: 14 nM).

    价 格:¥电议型 号:T6276产 地:中国大陆

  • T6275Obatoclax MesylateObatoclax;GX15-070;奥巴克拉盐酸盐

    Obatoclax is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3.

    价 格:¥电议型 号:T6275产 地:中国大陆

  • T6274RO4929097RG-4733

    RO4929097, a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).

    价 格:¥电议型 号:T6274产 地:中国大陆

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