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T62014(R,R)-BAY-Y 3118;化合物 (R,R)-BAY-Y 3118(R,R)-BAY-Y 3118
(R,R)-BAY-Y 3118, the R-enantiomer of BAY-Y 3118, exhibits weak bactericidal activity.
价 格:¥电议型 号:T62014产 地:中国大陆
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T62013PI3Kδ-IN-10;化合物 PI3Kδ-IN-10PI3Kδ-IN-10
PI3Kδ-IN-10 is a highly potent and orally active PI3Kδ inhibitor (IC50= 2 nM). In hepatocellular carcinoma models, PI3Kδ-IN-10 robustly suppresses the downstream AKT pathway to induce subsequent apoptosis.
价 格:¥电议型 号:T62013产 地:中国大陆
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T62012Antiproliferative agent-8;化合物 Antiproliferative agent-8Antiproliferative agent-8
Antiproliferative agent-8 (Compound 5a) is an anti-cancer compoundwith antiproliferative activity. Antiproliferative agent-8 can significantly increase the P53 levels.
价 格:¥电议型 号:T62012产 地:中国大陆
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T62011LDN-209929 dihydrochloride;化合物 LDN-209929 dihydrochlorideLDN-209929 dihydrochloride
LDN-209929 dihydrochloride is a potent and selective inhibitor of haspin kinase (IC50= 55 nM). LDN-209929 dihydrochloride shows180-fold selectivity verses DYRK2 (IC50= 9.9 μM).
价 格:¥电议型 号:T62011产 地:中国大陆
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T62010HIV-1 inhibitor-20;化合物 HIV-1 inhibitor-20HIV-1 inhibitor-20
HIV-1 inhibitor-20 is a potent HIV-1 inhibitor.
价 格:¥电议型 号:T62010产 地:中国大陆
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T6201Disufenton sodium;化合物NXY059Cerovive|||NXY059|||OKN007|||NXY-059|||NXY 059;Cerovive|||NXY059|||OKN007
Disufenton sodium (NXY-059), a new-type nitrone, exhibits potently neuroprotective effects.
价 格:¥电议型 号:T6201产 地:中国大陆
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T62009EGFR-IN-71;化合物 EGFR-IN-71EGFR-IN-71
EGFR-IN-71 is a potent inhibitor of epidermal growth factor receptor (EGFR) (IC50= 3.7 μM). EGFR-IN-71 has research value in chordoma.
价 格:¥电议型 号:T62009产 地:中国大陆
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T62008Mazaticol;化合物 MazaticolMazaticol
Mazaticol is an anticholinergic agent, which blocks the muscarinic acetylcholine receptors and cholinergic nerve activity. Mazaticol potently inhibits 3H-QNB and 3H-PZ binding. Mazaticol can bind to the M2 receptors with high affinity. Mazaticol shows inhibitory effects on dopamine uptake in the striatal nerve terminal. Mazaticol has research in parkinsonian syndrome.
价 格:¥电议型 号:T62008产 地:中国大陆
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T62007CXCR4 modulator-1;化合物 CXCR4 modulator-1CXCR4 modulator-1
CXCR4 modulator-1 (compound ZINC72372983) is a potent CXCR4 modulator (EC 50= 100 nM). CXCR4 modulator-1 has research value in anti-inflammatory, anticancer and anti-HIV.
价 格:¥电议型 号:T62007产 地:中国大陆
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T62006HDAC-IN-30;化合物 HDAC-IN-30HDAC-IN-30
HDAC-IN-30 is a multi-target HDAC inhibitor. HDAC-IN-30 inhibits HDAC1 (IC50 =13.4 nM), HDAC2 (IC50 =28.0 nM), HDAC3 (IC50 =9.18 nM), HDAC6 (IC50 =42.7 nM), HDAC8 (IC50 =131 nM). HDAC-IN-30 shows potent antitumor efficacy.
价 格:¥电议型 号:T62006产 地:中国大陆
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T62005Imidapril;化合物 ImidaprilImidapril
Imidapril (TA-6366 free base) is an orally active inhibitor of angiotensin-converting enzyme (ACE) and MMP-9. Imidapril inhibits the conversion of angiotensin I to angiotensin II, thereby reduces total peripheral resistance and systemic blood pressure. Imidapril has research value in hypertension, type 1 diabetic, nephropathy and chronic heart failure.
价 格:¥电议型 号:T62005产 地:中国大陆
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T62004(Rac)-Nebivolol;化合物 (Rac)-Nebivolol(Rac)-Nebivolol
(Rac)-Nebivolol ((Rac)-R 065824) is a racemic isomer of Nebivolol. Nebivolol is a selective antagonist of β1-adrenergic receptor (IC 50= 0.8 nM). Nebivolol shows Vasodilatory activity. In the early stages of ethanol-induced cardiac toxicity, Nebivolol can prevent up-regulation of Nox2/NADPH oxidase and lipoperoxidation.
价 格:¥电议型 号:T62004产 地:中国大陆
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T62003SOS1-IN-13;化合物 SOS1-IN-13SOS1-IN-13
SOS1-IN-13 is a potent inhibitor of son of sevenless homolog 1 (SOS1). SOS1-IN-13 shows IC 50 s of 6.5 nM and 327 nM for SOS1 and pERK, respectively. SOS1-IN-13 has research value in anticancer.
价 格:¥电议型 号:T62003产 地:中国大陆
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T62002Topoisomerase I inhibitor 7;化合物 Topoisomerase I inhibitor 7Topoisomerase I inhibitor 7
Topoisomerase I inhibitor 7 (Compound 8) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 7 significantly inhibits tumor growth (up to 79%) and increases the lifespan (153%) of mice bearing P388 lymphoma transplants.
价 格:¥电议型 号:T62002产 地:中国大陆
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T62001Pim-1 kinase inhibitor 2;化合物 Pim-1 kinase inhibitor 2Pim-1 kinase inhibitor 2
Pim-1 kinase inhibitor 2 (Compound 13), a potent inhibitor of Pim-1 kinase, has the potential for cancer research due to its ability to induce apoptosis [1].
价 格:¥电议型 号:T62001产 地:中国大陆
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T62000ABBV-318;化合物ABBV-318ABBV-318
ABBV-318 can be used as small molecule Nav1.7/Nav1.8 blockers for the treatment of pain, with IC50 values of 2.8 μM for hNav1.7 and 3.8 μM for hNav1.8. ABBV-318 can be used to study pain-related disorders.
价 格:¥电议型 号:T62000产 地:中国大陆
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T14127Adenosine A1 receptor activator T62;化合物Adenosine A1 receptor activator T62Adenosine A1 receptor acti
Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve-injury pain[1][2][3].
价 格:¥电议型 号:T14127产 地:中国大陆
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T12278NXT629;化合物 T12278NXT629
NXT629 is a selective and competitive antagonist of PPAR-α(human PPARα with an IC50 of 77 nM).
价 格:¥电议型 号:T12278产 地:中国大陆