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T62070HIV-1 inhibitor-31;化合物 HIV-1 inhibitor-31HIV-1 inhibitor-31
HIV-1 inhibitor-31 (compound 4) is a potent inhibitor of HIV-1. HIV-1 inhibitor-31 can be used in the study of AIDS.
价 格:¥电议型 号:T62070产 地:中国大陆
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T6207SC144;化合物SC144SC144
SC144 is an orally active small-molecule gp130 inhibitor.
价 格:¥电议型 号:T6207产 地:中国大陆
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T62069Chitinase-IN-4;化合物 Chitinase-IN-4Chitinase-IN-4
Chitinase-IN-4 (compound 8f) is a potent and selective inhibitor of OfChi-h with an IC50 value of 0.1 μM and good insecticidal activity.
价 格:¥电议型 号:T62069产 地:中国大陆
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T62068Chitin synthase inhibitor 1;化合物 Chitin synthase inhibitor 1Chitin synthase inhibitor 1
Chitin synthase inhibitor 1 is a potent and selective chitin synthase (CHS) inhibitor with IC50 of 0.12 mM. Chitin synthase inhibitor 1 potently inhibits drug-resistant fungi variants.
价 格:¥电议型 号:T62068产 地:中国大陆
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T62067TRPC5-IN-3;化合物 TRPC5-IN-3TRPC5-IN-3
TRPC5-IN-3 is a potent TRPC5 inhibitor (IC50= 10.75 nM).
价 格:¥电议型 号:T62067产 地:中国大陆
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T62066Antitubercular agent-29;化合物 Antitubercular agent-29Antitubercular agent-29
Antitubercular agent-29 (compound 6xa) is a potent drug resistant (DR) Mycobacterium tuberculosis (Mtb) inhibitor. Antitubercular agent-29 exhibits MIC of 0.03 μg/mL against drug-susceptible (DS)-Mtb strains, MIC of 0.03-0.06 μg/mL against DR-Mtb strains. Antitubercular has favourable selectivity (SI>40) against Vero cells.
价 格:¥电议型 号:T62066产 地:中国大陆
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T62065c-ABL-IN-4;化合物 c-ABL-IN-4c-ABL-IN-4
c-ABL-IN-4 is a potent inhibitor of c-Abl.
价 格:¥电议型 号:T62065产 地:中国大陆
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T62064PDE4B/7A-IN-2;化合物 PDE4B/7A-IN-2PDE4B/7A-IN-2
This compound is a dual 5-HT1A/5-HT7 receptor antagonist (5-HT1A Ki = 8 nM, Kb = 0.04 nM; 5-HT7 Ki = 451 nM, Kb = 460 nM) with additional inhibitory activity against PDE4B/PDE7A (PDE4B IC50 = 80.4 μM; PDE7A IC50 = 151.3 μM). Its antidepressant-like effect surpasses that of the reference agent, escitalopram.
价 格:¥电议型 号:T62064产 地:中国大陆
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T62063Antibacterial agent 76;化合物 Antibacterial agent 76Antibacterial agent 76
Antibacterial agent 76 (compound 9) is a potent antibacterial agent.
价 格:¥电议型 号:T62063产 地:中国大陆
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T62062MAO-B-IN-7;化合物 MAO-B-IN-7MAO-B-IN-7
MAO-B-IN-7 is a potent and blood-brain barrier permeable MAO-B and AChE inhibitor. MAO-B-IN-7 exhibits IC50 s of 41 nM, 87 nM and 0.3 μM for human AChE, electric eel AChE and MAO-B, respectively. MAO-B-IN-7 effectively alleviates oxidative stress and neuroinflammatory damage.
价 格:¥电议型 号:T62062产 地:中国大陆
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T62061COX-2-IN-6;COX-2抑制剂6COX-2-IN-6
COX-2-IN-6 is a potent, selective, and orally available cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 0.84 μM and a Ki of 69 nM.COX-2-IN-6 inhibits COX-2-driven PGE2 synthesis with an IC50 of 0.60 μM.COX-2-IN-6 is used to prevent colorectal cancer. COX-2-IN-6 can be used to prevent colorectal cancer.
价 格:¥电议型 号:T62061产 地:中国大陆
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T62060NF-κB-IN-5;化合物 NF-κB-IN-5NF-κB-IN-5
NF-κB-IN-5 (compound 4d) is an orally active NF-κB inhibitor. NF-κB-IN-5 interacts directly with NF-κB. NF-κB-IN-5 shows antitumor activity against human cancer cell lines, with IC 50 values of 5.35, 2.81, 2.83, 2.02 and 3.90 μM for HCT116, U87-MG, HepG2, BGC823, PC9, respectively.
价 格:¥电议型 号:T62060产 地:中国大陆
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T6206PHA-767491;化合物PHA767491CAY10572|||PHA767491|||PHA 767491;CAY10572|||PHA767491|||PHA 767491
PHA-767491 (CAY10572) is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.
价 格:¥电议型 号:T6206产 地:中国大陆
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T62059Influenza A virus-IN-6;化合物 Influenza A virus-IN-6Influenza A virus-IN-6
Influenza A virus-IN-6 (compound 16j) is a potent and selective inhibitor of influenza A virus (IC 50= 3.88 μM, CC50= 36.64 μM). Influenza A virus-IN-6 exhibits anti-IAV activity with low cytotoxicity.
价 格:¥电议型 号:T62059产 地:中国大陆
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T62058αβ-Tubulin-IN-1;化合物 αβ-Tubulin-IN-1αβ-Tubulin-IN-1
αβ-Tubulin-IN-1 is a potent and orally active inhibitor of αβ-Tubulin. αβ- Tubulin-IN-1 blocks cell cycle at G2/M phase and induces apoptosis. αβ-Tubulin-IN-1 inhibits tumor cell migration and metastasis. αβ-Tubulin-IN-1 exhibits significant antitumor efficacy.
价 格:¥电议型 号:T62058产 地:中国大陆
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T62057Anticancer agent 12;化合物 Anticancer agent 12Anticancer agent 12
Anticancer agent 12 shows cytotoxic activity in malignant cells with no hepatotoxicity.
价 格:¥电议型 号:T62057产 地:中国大陆
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T62056(E/Z)-Zotiraciclib hydrochloride;化合物 (E/Z)-Zotiraciclib hydrochloride(E/Z)-Zotiraciclib hydrochlorid
(E/Z)-Zotiraciclib ((E/Z)-TG02) hydrochloride is a potent inhibitor of CDK2, JAK2, and FLT3.
价 格:¥电议型 号:T62056产 地:中国大陆
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T62055NVS-BET-1;化合物 NVS-BET-1NVS-BET-1
NVS-BET-1 is a BET bromodomain inhibitor. NVS-BET-1 can regulate keratinocyte plasticity.
价 格:¥电议型 号:T62055产 地:中国大陆
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T62054D4R antagonis-2;化合物 D4R antagonis-2D4R antagonis-2
D4R antagonist-2 is a potent and selective D4R antagonist (IC50= 6.52 μM). D4R antagonist-2 displays favorable in vitro PK parameters and exhibits good brain penetration. D4R antagonist-2 has the research potential in Parkinson’s disease.
价 格:¥电议型 号:T62054产 地:中国大陆
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T62053Lorpucitinib;化合物LorpucitinibJNJ-64251330;JNJ-64251330
Lorpucitinib (JNJ-64251330) is an orally available, selective and potent JAK kinase inhibitor for the study of inflammatory and gastrointestinal disorders associated with Janus kinase (JAK) signaling.
价 格:¥电议型 号:T62053产 地:中国大陆