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T62127AMPA-IN-1;化合物 AMPA-IN-1AMPA-IN-1
AMPA-IN-1 is a potent inhibitor of AMPA receptors, a widely expressed receptor in the brain with a central role in the regulation of rapid excitatory synaptic transmission and synaptic plasticity. 14).
价 格:¥电议型 号:T62127产 地:中国大陆
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T62126(Rac)-NMDAR antagonist 1;化合物 (Rac)-NMDAR antagonist 1(Rac)-NMDAR antagonist 1
(Rac)-NMDAR antagonist 1 is a racemate of NMDAR antagonist 1. NMDAR antagonist 1 is a potent, orally active, NR2B-selective NMDAR antagonist.
价 格:¥电议型 号:T62126产 地:中国大陆
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T62125Colistin adjuvant-1;化合物 Colistin adjuvant-1Colistin adjuvant-1
Colistin adjuvant-1 is a mucin adjuvant with enhanced mucin-enhancing activity against gram-negative bacteria. colistin adjuvant-1 exhibits inhibition of NF-κB (IC50: 0.209 μM).
价 格:¥电议型 号:T62125产 地:中国大陆
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T62124Anticancer agent 80;化合物 Anticancer agent 80Anticancer agent 80
Anticancer agent 80 (Compound 3c) is an anticancer agent that exhibits a significant dark toxic effect on T47-D (IC50: 10.14 μM).
价 格:¥电议型 号:T62124产 地:中国大陆
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T62123FNDR-20123;化合物 FNDR-20123FNDR-20123
FNDR-20123 is the first safe and effective anti-malarial HDAC inhibitor, acting on both Plasmodium falciparum HDAC (IC50: 31 nM) and human HDAC (IC50: 3 nM). FNDR-20123 inhibited HDAC1 (IC50: 25 nM), HDAC2 (IC50: 29 nM), HDAC3 (IC50: 2 nM), HDAC6 (IC50: 11 nM), HDAC8 (IC50: 282 nM) and, at nanomolar concentrations, HDAC3 (IC50: 2 nM). The inhibitor of HDAC subtype III was also observed at nanomolar concentrations.
价 格:¥电议型 号:T62123产 地:中国大陆
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T62122Chitinase-IN-5;化合物 Chitinase-IN-5Chitinase-IN-5
Chitinase-IN-5 (8i) is a potent inhibitor of the chitinase OfChi-h (IC50: 0.051 μM) and has good insecticidal properties.Chitinase-IN-5 can be used to study green pest control and management.
价 格:¥电议型 号:T62122产 地:中国大陆
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T62121Tubulin polymerization-IN-3;化合物 Tubulin polymerization-IN-3Tubulin polymerization-IN-3
Tubulin polymerization-IN-3 is a potent inhibitor of microtubulin polymerization (IC50: 3.84 μM) and induces apoptosis in colon cancer cells.
价 格:¥电议型 号:T62121产 地:中国大陆
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T62120Antibacterial agent 79;化合物 Antibacterial agent 79Antibacterial agent 79
Antibacterial agent 79 is an antibacterial agent.
价 格:¥电议型 号:T62120产 地:中国大陆
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T62119Lasofoxifene;化合物 LasofoxifeneLasofoxifene
Lasofoxifene (CP-336156) is a selective, orally active estrogen receptor modulator (SERM) that inhibits the growth and metastasis of primary tumours and is also anti-osteoporotic.
价 格:¥电议型 号:T62119产 地:中国大陆
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T62118KIF18A-IN-4;化合物 KIF18A-IN-4KIF18A-IN-4
KIF18A-IN-4 is a moderately potent non-competitive KIF18A inhibitor of ATP and microtubule with an IC50 of 6.16 μM. KIF18A-IN-4 selectively acts on a large number of mitotic kinesins and kinases, with no direct effect on microtubule protein assembly. KIF18A-IN-4 shows anti-tumour effects.
价 格:¥电议型 号:T62118产 地:中国大陆
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T62117ALK5-IN-34;化合物 ALK5-IN-34ALK5-IN-34
ALK5-IN-34 is a selective, orally active inhibitor of activin receptor-like kinase (ALK), which inhibits the activity of activin receptor-like kinase (IC50 ≤ 10 nM) and also inhibits tumour growth.
价 格:¥电议型 号:T62117产 地:中国大陆
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T62116ALK5-IN-33;化合物 ALK5-IN-33ALK5-IN-33
ALK5-IN-33 (Compound EX-10) is an orally active, selective inhibitor of ALK-5 (IC50 ≤ 10 nM).
价 格:¥电议型 号:T62116产 地:中国大陆
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T62115HBV-IN-24;化合物 HBV-IN-24HBV-IN-24
HBV-IN-24 (compound (2 S, 6S)-1a) is a potent inhibitor of HBV. HBV-IN-24 is a strong inhibitor of HBV DNA (EC50: 0.6 nM), HBsAg (EC50: 0.6 nM) and HBeAg (EC50: 4.6 nM). antiviral effect and was able to improve neurotoxicity.
价 格:¥电议型 号:T62115产 地:中国大陆
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T62114JAK3-IN-12;化合物 JAK3-IN-12JAK3-IN-12
JAK3-IN-12 (compound 15k) is a potent inhibitor of JAK3 (IC50: 9.5 nM) and can be used in the study of rheumatoid arthritis.
价 格:¥电议型 号:T62114产 地:中国大陆
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T62113EGFR-IN-49;化合物 EGFR-IN-49EGFR-IN-49
EGFR-IN-49 is a potent and selective EGFR inhibitor that acts on EGFRT790M (IC50: 65.0 nM) and EGFRT790M/L858R (IC50: 13.6 nM). EGFR-IN-49 induces apoptosis in a dose-dependent manner.
价 格:¥电议型 号:T62113产 地:中国大陆
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T62112CDK8-IN-6;化合物 CDK8-IN-6CDK8-IN-6
CDK8-IN-6 (compound 9) is a potent inhibitor of cyclin-dependent kinase 8 (CDK8) (Kd: 13 nM), CDK8-IN-6 showed potential research value in AML cancers.
价 格:¥电议型 号:T62112产 地:中国大陆
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T62111Antioxidant agent-5;化合物 Antioxidant agent-5Antioxidant agent-5
Antioxidant agent-5 (compound D-6) is a potent antioxidant. antioxidant agent-5 inhibits oxLDL-induced increases in ROS levels and NF-κB nuclear translocation. antioxidant agent-5 inhibits oxLDL (oxidized LDL)-induced apoptosis (VECs). Antioxidant agent-5 activates the Nrf2/HO-1 antioxidant pathway and exhibits protective activity against oxLDL-induced endothelial damage.
价 格:¥电议型 号:T62111产 地:中国大陆
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T62110MK2-IN-4;化合物 MK2-IN-4MK2-IN-4
MK2-IN-4 is a MAPKAPK2 (MK2) inhibitor (IC50: 45 nM). MK2-IN-4 can be used in cancer, inflammation and immunology studies.
价 格:¥电议型 号:T62110产 地:中国大陆
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T6211Posaconazole;泊沙康唑SCH 56592|||POS;泊沙康唑|||SCH 56592|||POS
Posaconazole (POS) is a sterol C14ɑ demethylase inhibitor (IC50: 0.25 nM).
价 格:¥电议型 号:T6211产 地:中国大陆
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T62109HDAC-IN-31;化合物 HDAC-IN-31HDAC-IN-31
HDAC-IN-31 is a selective, potent, orally active HDAC inhibitor that acts on HDAC1 (IC50: 84.90 nM), HDAC2 (IC50: 168.0 nM), HDAC3 (IC50: 442.7 nM), HDAC8 (IC50>10000 nM). HDAC-IN-31 has good anti-tumour effects. HDAC-IN-31 has shown potential research value in diffuse large B-cell lymphoma.
价 格:¥电议型 号:T62109产 地:中国大陆