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T62185GABA-AT-IN-1;化合物 GABA-AT-IN-1GABA-AT-IN-1
GABA-AT-IN-1 (Compound 6) is an inhibitor of γ-aminobutyric acid transaminase (GABA-AT) that crosses the blood-brain barrier.
价 格:¥电议型 号:T62185产 地:中国大陆
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T62184NRX-2663;化合物 NRX-2663NRX-2663
NRX-2663 is an enhancer of the interaction of β-catenin with the homologous E3 ligaseSCFβ-TrCP and has an enhanced effect on the binding of β-catenin to β-TrCP (Kd: 54.8 nM, EC50: 22.9 nM).
价 格:¥电议型 号:T62184产 地:中国大陆
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T62183IL-2-IN-1;IL-2 抑制剂 1IL-2-IN-1
IL-2-IN-1 is an IL-2 inhibitor with antiproliferative activity for the study of diseases caused by abnormalities in the immune system.
价 格:¥电议型 号:T62183产 地:中国大陆
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T62182NIC-0102;化合物 NIC-0102NIC-0102
NIC-0102 is an orally active proteasome inhibitor (pIC50:7.55) that exhibits specific inhibition of NLRP3 inflammatory vesicle activation. Inhibitory effect.
价 格:¥电议型 号:T62182产 地:中国大陆
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T62181BACE-IN-1;化合物 BACE-IN-1BACE-IN-1
BACE-IN-1 is an imidazo[1,2-a]pyridine derivative that inhibits the β-site amyloid precursor protein cleavage enzyme (BACE) sentence.BACE-IN-1 has the potential to investigate diseases involving BACE, such as Alzheimer´s disease.
价 格:¥电议型 号:T62181产 地:中国大陆
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T62180CB1/2 agonist 2;化合物 CB1/2 agonist 2CB1/2 agonist 2
CB1/2 agonist 2 (compound 23) is a potent non-selective cannabinoid ligand with Ki of 3.5 nM and 1.2 nM, respectively. CB1/2 agonist 2 is a full agonist of CB1 and a competitive inverse agonist of CB2. BACE-IN-1 is a complete agonist of CB1 and a competitive inverse agonist of CB2.
价 格:¥电议型 号:T62180产 地:中国大陆
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T6218Selumetinib;司美替尼ARRY-142886|||AZD6244;ARRY-142886|||司美替尼|||AZD6244
Selumetinib (AZD6244) (AZD6244) is an effective, specific inhibitor of MEK1 and ERK1/2 phosphorylation (IC50: 14/10 nM).
价 格:¥电议型 号:T6218产 地:中国大陆
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T62178TLR7/8 antagonist 1;化合物 TLR7/8 antagonist 1TLR7/8 antagonist 1
TLR7/8 Antagonist 1 (Compound 16c), an imidazoquinoline derivative, is a potent TLR7/8 agonist with IC50 values of 3.91 and 2.19 μM for TLR7 and TLR8, respectively. rel-O-2050 (TLR-2050) is a key target for drug development in infectious diseases, cancer and autoimmune diseases.
价 格:¥电议型 号:T62178产 地:中国大陆
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T62177TLR7/8 agonist 6;化合物 TLR7/8 agonist 6TLR7/8 agonist 6
TLR7/8 agonist 6 (Compound 4), an imidazoquinoline derivative, is a potent TLR7/8 agonist with IC50 values of 0.18 and 5.34 μM for TLR7 and TLR8, respectively. TLR7/8 Antagonist
价 格:¥电议型 号:T62177产 地:中国大陆
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T62176POLA1 inhibitor 1;化合物 POLA1 inhibitor 1POLA1 inhibitor 1
POLA1 inhibitor 1 (Compound 12) is an orally active inhibitor of POLA1. POLA1 inhibitor 1 exhibits antitumour effects on several tumour tissue types and Adaroten-resistant cell lines.
价 格:¥电议型 号:T62176产 地:中国大陆
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T62175COX-2-IN-8;化合物 COX-2-IN-8COX-2-IN-8
COX-2-IN-8 (Compound 6a) is a potent, selective, orally active COX-2 inhibitor (IC50: 6.585 μM) with a higher COX-2 selectivity than Celecoxib.
价 格:¥电议型 号:T62175产 地:中国大陆
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T62174Protein deglycase DJ-1 against-1;化合物 Protein deglycase DJ-1 against-1Protein deglycase DJ-1 against-
Protein deglycase DJ-1 against-1 is a DJ-1-binding compound that crosses the blood-brain barrier and targets DJ1 in a dependent manner. protein deglycase DJ-1 against-1 is a neuroprotective agent with potential for Parkinson´s disease studies.
价 格:¥电议型 号:T62174产 地:中国大陆
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T62173GPR41 agonist-1;化合物 GPR41 agonist-1GPR41 agonist-1
GPR41 agonist-1 (compound 9) is a potent agonist of GPR41 and can be used in studies of insulin-related diseases.
价 格:¥电议型 号:T62173产 地:中国大陆
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T62172Dual AChE-MAO B-IN-1;化合物 Dual AChE-MAO B-IN-1Dual AChE-MAO B-IN-1
Dual AChE-MAO B-IN-1 (compound 15) is a safe, metabolically stable neuroprotective agent.Dual AChE-MAO B-IN-1 is a potent, orally active CNS-permeable inhibitor of human AChE (IC50=550 nM) and MAO-B (IC50=8.2 nM), and has low in vitro activity against AChE and MAO-B with IC50 values of 550 nM, 8.2 nM respectively.
价 格:¥电议型 号:T62172产 地:中国大陆
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T62171HDAC8/BRPF1-IN-1;化合物 HDAC8/BRPF1-IN-1HDAC8/BRPF1-IN-1
HDAC8/BRPF1-IN-1 (Compound 23a) is a dual HDAC8 and BRPF1 inhibitor that acts on human HDAC8 (IC50: 443 nM) and human BRPF1 (Kd: 67 nM). HDAC8/BRPF1-IN-1 has low in vitro activity against HDAC1 and 6.
价 格:¥电议型 号:T62171产 地:中国大陆
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T6217LFM-A13;化合物LFM-A13LFM-A13
LFM-A13(IC50=2.5 μM), a specific Bruton´s tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.
价 格:¥电议型 号:T6217产 地:中国大陆
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T62169Antibacterial agent 72;化合物 Antibacterial agent 72Antibacterial agent 72
Antibacterial agent 72 has an antibacterial effect by selectively acting on bacterial membranes.
价 格:¥电议型 号:T62169产 地:中国大陆
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T62168ML138;化合物 ML138ML138
ML138 is a probe for MLPCN, an agonist of the κ opioid receptor.
价 格:¥电议型 号:T62168产 地:中国大陆
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T62167BI-10;化合物 BI-10BI-10
BI-10 is an antifungal compound that, in combination with fluconazole, inhibits mycelial growth, accumulates ROS, reduces mitochondrial membrane potential (MMP) and alters membrane permeability.
价 格:¥电议型 号:T62167产 地:中国大陆
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T62166KDOAM-25 trihydrochloride;化合物 KDOAM-25 trihydrochlorideKDOAM-25 trihydrochloride
KDOAM-25 trihydrochloride is a potent and highly selective inhibitor of histone lysine demethylase 5 (KDM5), acting on KDM5A (IC50: 71 nM), KDM5B (IC50: 19 nM), KDM5C (IC50: 69 nM), KDM5D (IC50: 69 nM). KDOAM-25 trihydrochloride enhances overall H3K4 methylation at the transcription start site and hinders the proliferation of multiple myeloma MM1S cells.
价 格:¥电议型 号:T62166产 地:中国大陆