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  • T6260AMG-208AMG-208,AMG208,AMG 208

    AMG 208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1.

    价 格：￥电议型 号：T6260产 地：美洲

  • T6261CP-466722CP-466722,CP466722,CP 466722

    CP-466722, an effective and reversible ATM inhibitor, does not inhibit ATR and PI3K or PIKK family members in cells.

    价 格：￥电议型 号：T6261产 地：美洲

  • T6270Trichostatin ATrichostatin A,TSA,

    Trichostatin A is a natural derivative of dienohydroxamic acid isolated from species of the bacterial genus Streptomyces. Trichostatin A (TSA) reversibly and specifically inhibits histone deacetylases, resulting in hyperacetylation of core histones which

    价 格：￥电议型 号：T6270产 地：美洲

  • T6271TipifarnibTipifarnib,R115777,IND 58359

    Tipifarnib is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting

    价 格：￥电议型 号：T6271产 地：美洲

  • T6272Fosbretabulin DisodiumFosbretabulin Disodium,CA 4P,Combretastatin A4 disodium phosphate

    Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium, a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM). Fosbretabulin Disodium inhibits the polymerization of tubulin (IC50: 2.4 μ

    价 格：￥电议型 号：T6272产 地：美洲

  • T6273DMXAADMXAA,ASA-404,Vadimezan

    Vadimezan is a fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity. Vadimezan induces the cytokines tumor necrosis alpha (TNF-alpha), serotonin and nitric oxide, resulting in hemorrhagic necrosis and a decrease in angiog

    价 格：￥电议型 号：T6273产 地：美洲

  • T6274RO4929097RO4929097,RG-4733,

    RO4929097, a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).

    价 格：￥电议型 号：T6274产 地：美洲

  • T6275Obatoclax MesylateObatoclax Mesylate,GX15-070,Obatoclax

    Obatoclax is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3.

    价 格：￥电议型 号：T6275产 地：美洲

  • T6276NU7441NU7441,KU-57788,

    NU7441 (KU-57788) is a highly effective and specific DNA-PK inhibitor (IC50: 14 nM).

    价 格：￥电议型 号：T6276产 地：美洲

  • T6277DoramapimodDoramapimod,BIRB 796,

    Doramapimod is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.

    价 格：￥电议型 号：T6277产 地：美洲

  • T6278SotrastaurinSotrastaurin,AEB071,

    Sotrastaurin is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).

    价 格：￥电议型 号：T6278产 地：美洲

  • T6279Givinostat hydrochloride monohydrateGivinostat hydrochloride monohydrate,ITF-2357 hydrochloride mono

    Givinostat hydrochloride monohydrate is an HDAC inhibitor.

    价 格：￥电议型 号：T6279产 地：美洲

  • T6280EnzastaurinEnzastaurin,LY317615,

    Enzastaurin (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.

    价 格：￥电议型 号：T6280产 地：美洲

  • T6281TW-37TW-37,TW37,TW 37

    TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM).

    价 格：￥电议型 号：T6281产 地：美洲

  • T6282GSK461364GSK461364,GSK461364A,

    GSK461364(Ki=2.2 nM) inhibits purified Plk1 .The specificity of GSK461364 for Plk1 is more than 1000-fold over Plk2/3.

    价 格：￥电议型 号：T6282产 地：美洲

  • T6283WortmanninWortmannin,KY-12420,SL-2052

    Wortmannin is the first described PI3K inhibitor with IC50 of 3 nM, with little selectivity within the PI3K family. Also blocks autophagosome formation and potently inhibits DNA-PK/ATM with IC50 of 16 nM and 150 nM.

    价 格：￥电议型 号：T6283产 地：美洲

  • T6284OnalespibOnalespib,AT13387,Onalespib (AT13387)

    Onalespib is a synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Onalespib selectively binds to Hsp90, thereby inhibiting its chaperone function and promoting the degradation

    价 格：￥电议型 号：T6284产 地：美洲

  • T6285GSK690693GSK690693

    GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.

    价 格：￥电议型 号：T6285产 地：美洲

  • T6287TariquidarTariquidar,XR9576,

    Tariquidar(Kd=5.1 nM) is a specific and effective non-competitive inhibitor of P-glycoprotein. It can reverse drug resistance in MDR cell Lines.

    价 格：￥电议型 号：T6287产 地：美洲

  • T6289DovitinibDovitinib,TKI258,CHIR-258

    Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 nM), also effective to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs (IC50: 8-13 nM), less potent to EGFR, InsR, EphA2, c-Met, IGF-1R, Tie2, and HER

    价 格：￥电议型 号：T6289产 地：美洲

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