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T62967Anti-inflammatory agent 10;化合物 Anti-inflammatory agent 10Anti-inflammatory agent 10
Anti-inflammatory agent 10 is a tilomisole-based benzimidazole-thiazole derivative that is orally active. anti-inflammatory agent 10 is more active against COX-2 enzymes than COX-1.
价 格:¥电议型 号:T62967产 地:中国大陆
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T62966IQTub4P;化合物 IQTub4PIQTub4P
IQTub4P is a potent inhibitor of microtubules. IQTub4P exhibits cytotoxicity in HeLa cells (EC50: 170 nM).
价 格:¥电议型 号:T62966产 地:中国大陆
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T62965TDP1 Inhibitor-2;化合物 TDP1 Inhibitor-2TDP1 Inhibitor-2
TDP1 Inhibitor-2 is a potent inhibitor of TDP1 (tyrosyl-DNA phosphodiesterase 1) (IC50: 99 nM) and inhibits SCAN1 (spinal cerebellar ataxia syndrome with axonal neuropathy) (IC50: 3.5 μM).
价 格:¥电议型 号:T62965产 地:中国大陆
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T62964AdipoRon hydrochloride;化合物 AdipoRon hydrochlorideAdipoRon hydrochloride
AdipoRon hydrochloride is a specific, orally active AdipoR agonist, capable of binding AdipoR1 (Kd: 1.8 μM) and AdipoR2 (Kd: 3.1 μM).
价 格:¥电议型 号:T62964产 地:中国大陆
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T62963Xanthine amine congener hydrochloride;化合物 Xanthine amine congener hydrochlorideXanthine amine congen
Xanthine amine congener (XAC) hydrochloride is a non-selective adenosine receptor antagonist that induces convulsions in mice.
价 格:¥电议型 号:T62963产 地:中国大陆
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T62962Axl-IN-3;化合物 Axl-IN-3Axl-IN-3
Axl-IN-3 is a selective, potent and orally active inhibitor of AXL kinase (IC50: 41.5 nM) and has a low inhibitory effect on other kinases.
价 格:¥电议型 号:T62962产 地:中国大陆
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T62961ZK824859 hydrochloride;化合物 ZK824859 hydrochlorideZK824859 hydrochloride
ZK824859 hydrochloride is a selective, orally active inhibitor of urokinase-type fibrinogen activator (uPA) with IC50 values of 79 nM, 1580 nM and 1330 nM for human uPA, tPA and fibrin, respectively.
价 格:¥电议型 号:T62961产 地:中国大陆
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T6296RAF265;化合物RAF265CHIR-265;CHIR-265
RAF265 (CHIR-265) (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM. Phase 2.
价 格:¥电议型 号:T6296产 地:中国大陆
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T62959LRH-1 modulator-1;化合物 LRH-1 modulator-1LRH-1 modulator-1
LRH-1 modulator-1 is a potent modulator/agonist of LRH-1 (liver receptor homolog-1). LRH-1 modulator-1 induces the anti-inflammatory cytokine IL-10 and exhibits inhibition of the inflammatory cytokines IL-1b and TNFa. LRH-1 modulator-1 has anti-inflammatory activity in intestinal-like organs.
价 格:¥电议型 号:T62959产 地:中国大陆
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T62958SARS-CoV-2-IN-31;化合物 SARS-CoV-2-IN-31SARS-CoV-2-IN-31
SARS-CoV-2-IN-31 is a potent inhibitor of COVID-19. SARS-CoV-2-IN-31 shows excellent to mild activity (IC50: 28.84-38.36 μM) against a variety of cancer cell lines. SARS-CoV-2-IN-31 can be used in cancer research.
价 格:¥电议型 号:T62958产 地:中国大陆
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T62957MRK-740;化合物MRK-740MRK-740
MRK-740 is a potent and selective inhibitor of PRDM9 histone methyltransferase.MRK-740 inhibits other histone methyltransferases and inhibits PRDM9-dependent H3K4 trimethylation.
价 格:¥电议型 号:T62957产 地:中国大陆
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T62956RORγt inverse agonist 29;化合物 RORγt inverse agonist 29RORγt inverse agonist 29
RORγt inverse agonist 29 is a potent, selective, orally active RORγt inverse agonist with an IC50 value of 21 nM. RORγt inverse agonist 29 can be used in the study of autoimmune diseases such as skin inflammation and psoriasis.
价 格:¥电议型 号:T62956产 地:中国大陆
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T62955PARP1-IN-5;化合物 PARP1-IN-5PARP1-IN-5
PARP1-IN-5 is a potent, selective, orally active, low-toxicity PARP-1 inhibitor with an IC50 value of 14.7 nM. PARP1-IN-5 can be used in cancer research.
价 格:¥电议型 号:T62955产 地:中国大陆
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T62954Ferroportin-IN-1;化合物 Ferroportin-IN-1Ferroportin-IN-1
Ferroportin-IN-1 is an inhibitor of the iron transport protein ferroportin and can be used to study diseases such as thalassaemia, sickle cell disease and haemochromatosis due to iron deficiency or disorders of iron metabolism.
价 格:¥电议型 号:T62954产 地:中国大陆
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T62953Estrogen receptor antagonist 6;化合物 Estrogen receptor antagonist 6Estrogen receptor antagonist 6
Estrogen receptor antagonist 6 is a potent antagonist of the Estrogen receptor. Estrogen receptor is a ligand-activated transcriptional regulatory protein that interacts with endogenous estrogens and mediates the induction of a variety of biological effects. Compound 166).
价 格:¥电议型 号:T62953产 地:中国大陆
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T62952Estrogen receptor antagonist 5;化合物 Estrogen receptor antagonist 5Estrogen receptor antagonist 5
Estrogen receptor antagonist 5 is a potent antagonist of the Estrogen receptor. Estrogen receptor (Estrogen receptor) is a ligand-activated transcriptional regulatory protein that interacts with endogenous estrogens and mediates the induction of a variety of biological effects. estrogen receptor antagonist 5 has potential for metastatic disease studies.
价 格:¥电议型 号:T62952产 地:中国大陆
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T62951Aldose reductase-IN-2;化合物 Aldose reductase-IN-2Aldose reductase-IN-2
Aldose reductase-IN-2 (Compound 5f) is a potent inhibitor of aldose reductase (AR) with antioxidant properties. aldose reductase-IN-2 is a promising anti-diabetic complication drug.
价 格:¥电议型 号:T62951产 地:中国大陆
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T62950IRAK4-IN-18;化合物 IRAK4-IN-18IRAK4-IN-18
IRAK4-IN-18 is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK4) (IC50: 15 nM). IRAK4-IN-18 inhibits LPS-induced IL23 production in THP and DC cells and blocks the development of arthritis in rats, a model of arthritis. IRAK4-IN-18 can be used to study arthritic diseases.
价 格:¥电议型 号:T62950产 地:中国大陆
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T6295Dabigatran;达比加群BIBR 953|||BIBR 953ZW;BIBR 953|||BIBR 953ZW|||达比加群
Dabigatran (BIBR 953ZW) is a THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk of stroke and systemic EMBOLISM in patients with nonvalvular atrial fibrillation.
价 格:¥电议型 号:T6295产 地:中国大陆
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T62949(1R,3S)-THCCA-Asn;化合物 (1R,3S)-THCCA-Asn(1R,3S)-THCCA-Asn
(1R,3S)-THCCA-Asn (4j) is a selective inhibitor of thrombin (IC50: 0.07-0.14 μM) with anti-thrombotic effects.
价 格:¥电议型 号:T62949产 地:中国大陆