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T6291WZ4003；化合物WZ4003WZ4003
WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively. It is no significant inhibition on 139 other kinases.
价 格：￥电议型 号：T6291产 地：中国大陆
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T62909SGC agonist 2；化合物 SGC agonist 2SGC agonist 2
SGC agonist 2 is a potent soluble guanylate cyclase (SGC) agonist. SGC agonist 2 has potential for cardiovascular disease (heart failure, angina, pulmonary hypertension, myocardial infarction) and fibrotic disease (renal fibrosis, systemic sclerosis).
价 格：￥电议型 号：T62909产 地：中国大陆
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T62908DENV-IN-6；化合物 DENV-IN-6DENV-IN-6
DENV-IN-6 is a potent inhibitor of DENV (I-IV), demonstrating EC50 values of 17.5, 13.20, 6.8, and 11.41 μM for the inhibition of DENV (I-IV) replication, respectively. Additionally, it exhibits anti-HIV-1 IIIB activity, with an EC50 of 0.0181 ?M and a CC50 of 64.92 ?M [1].
价 格：￥电议型 号：T62908产 地：中国大陆
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T62907TAS-117 hydrochloride；化合物 TAS-117 hydrochlorideTAS-117 hydrochloride
TAS-117 hydrochloride is a selective, potent, orally active allosteric Akt inhibitor, acting on Akt1 (IC50: 4.8 nM), Akt2 (IC50: 1.6 nM) and Akt3 (IC50: 44 nM). TAS-117 hydrochloride stimulates anti-myeloma activity, enhances lethal endoplasmic reticulum stress induced by proteasome inhibition, and can induce apoptosis and autophagy.
价 格：￥电议型 号：T62907产 地：中国大陆
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T62906Lazuvapagon；化合物 LazuvapagonLazuvapagon
Lazuvapagon is a vasopressin V2 receptor agonist that can be used to study enuresis.
价 格：￥电议型 号：T62906产 地：中国大陆
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T62905GLS-1-IN-1；化合物 GLS-1-IN-1GLS-1-IN-1
GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor that inhibits Hep G2, MCF 7 and MCF 10A cells.
价 格：￥电议型 号：T62905产 地：中国大陆
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T62904PknB-IN-2；化合物 PknB-IN-2PknB-IN-2
PknB-IN-2 (Compound 10) is an inhibitor of Mycobacterium tuberculosis protein kinase B (PknB) (IC50: 12.1 μM).
价 格：￥电议型 号：T62904产 地：中国大陆
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T62903Enpp-1-IN-6；化合物 Enpp-1-IN-6Enpp-1-IN-6
Enpp-1-IN-6 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1). Enpp-1-IN-6 has the potential to be used in cancer and infectious disease research.
价 格：￥电议型 号：T62903产 地：中国大陆
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T62902NDI-034858；化合物NDI-034858TAK-279|||NDI-03485；TAK-279|||NDI-03485
NDI-034858 (TAK-279) is a tyrosine kinase 2 (TYK2) inhibitor (Kd<200 pM) that targets the JH2 structural domain of Tyk2 for the treatment of autoimmune diseases caused by aberrant expression of IL12 and IL23.
价 格：￥电议型 号：T62902产 地：中国大陆
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T62901VEGFR-2-IN-27；化合物 VEGFR-2-IN-27VEGFR-2-IN-27
VEGFR-2-IN-27 (compound 7a) is a potent inhibitor of VEGFR-2 (IC50: 14.8 nM) and can be used in anticancer studies.
价 格：￥电议型 号：T62901产 地：中国大陆
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T62900PDE10-IN-5；化合物 PDE10-IN-5PDE10-IN-5
PDE10-IN-5 is a phosphodiesterase 10 (PDE 10) inhibitor that can be used to study certain central nervous system disorders.
价 格：￥电议型 号：T62900产 地：中国大陆
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T6290Tanespimycin；坦螺旋霉素17-AAG|||CP 127374|||NSC 330507|||KOS 953；坦螺旋霉素|||17-AAG|||CP 127374|||NSC 330507|
Tanespimycin (KOS 953) (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell Hsp90 (IC50: 5 nM).
价 格：￥电议型 号：T6290产 地：中国大陆
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T62899Tau-aggregation and neuroinflammation-IN-1；Tau蛋白聚集体和神经炎症抑制剂1Tau-aggregation and neuroinflammation-IN
Tau-aggregation and neuroinflammation-IN-1 is a potent inhibitor of tau protein aggregates, showing significant inhibitory activity against AcPHF6 and full-length tau protein aggregates. Tau-aggregation and neuroinflammation-IN-1 has anti-inflammatory activity and reduces NO release.Tau-aggregation and neuroinflammation-IN-1 has low cytotoxicity against LSP-stimulated BV2 cells.Tau-aggregation and neuroinflammation-IN-1 reverses okadaic acid-induced memory impairment in rats.
价 格：￥电议型 号：T62899产 地：中国大陆
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T62898Glucosylceramide synthase-IN-1；化合物 Glucosylceramide synthase-IN-1Glucosylceramide synthase-IN-1
Glucosylceramide synthase-IN-1 (T-036) is a potent, orally active, blood-brain barrier permeable glucosylceramide synthase (GCS) inhibitor that acts on human GCS (IC50: 31 nM) and mouse GCS (IC50: 51 nM). Glucosylceramide synthase-IN-1 can be used to study Gaucher disease.
价 格：￥电议型 号：T62898产 地：中国大陆
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T62897MtTMPK-IN-3；化合物 MtTMPK-IN-3MtTMPK-IN-3
MtTMPK-IN-3 (compound 25) is a potent inhibitor of Mycobacterium tuberculosis thymidylate kinase (MtTMPK) with an IC50 value of 0.12 μM. It also demonstrates inhibitory activity against Mtb H37Rv with a MIC of 12.5 μM and exhibits a degree of cytotoxicity in MRC-5 human fibroblast cells (EC50 = 12.5 μM). This compound is useful for tuberculosis research [1].
价 格：￥电议型 号：T62897产 地：中国大陆
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T62896EZH2-IN-12；化合物 EZH2-IN-12EZH2-IN-12
EZH2-IN-12 (Compound 5) is a potent inhibitor of EZH2, which has potential for studies of CNS malignancies.
价 格：￥电议型 号：T62896产 地：中国大陆
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T62895DNA Gyrase-IN-4；化合物 DNA Gyrase-IN-4DNA Gyrase-IN-4
DNA Gyrase-IN-4 (compound 8p) is a potent inhibitor of DNA cyclooxygenase (IC50: 0.13 μM). (MIC: 0.05 μg/ml), Salmonella (MIC: 0.05 μg/ml) and Escherichia coli (MIC: 8 μg/ml).
价 格：￥电议型 号：T62895产 地：中国大陆
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T62894AZ-PFKFB3-67 quarterhydrate；化合物 AZ-PFKFB3-67 quarterhydrateAZ-PFKFB3-67 quarterhydrate
AZ-PFKFB3-67 quarterhydrate is a selective and potent inhibitor of the metabolic kinase PFKFB3 kinase, acting on PFKFB3 (IC50: 11 nM), PFKFB2 (IC50: 159 nM) and PFKFB1 (IC50: 1130 nM).
价 格：￥电议型 号：T62894产 地：中国大陆
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T62893SM-2470；化合物 SM-2470SM-2470
SM-2470 is an α1-adrenoceptor antagonist with antihypertensive activity that decreases anterior ganglionic adrenal nerve activity and aortic descending nerve activity.SM-2470 has hypocholesterolemic activity and inhibits cholesterol absorption.
价 格：￥电议型 号：T62893产 地：中国大陆
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T62892hCAI/II-IN-1；化合物 hCAI/II-IN-1hCAI/II-IN-1
hCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor that acts on hCA I (IC50: 0.047 μM) and hCA II (IC50: 0.024 μM).
价 格：￥电议型 号：T62892产 地：中国大陆
