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T62836Hit 1；化合物 Hit 1Hit 1
Hit 1 is an activator of insulin-degrading enzymes (IDE) (EC50: 5.5 μM) and reduces glucose-stimulated insulin secretion.
价 格：￥电议型 号：T62836产 地：中国大陆
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T62835Antitumor agent-54；化合物 Antitumor agent-54Antitumor agent-54
Antitumor agent-54 (Compound C11) is a 14-3-3η protein inhibitor (KD: 35 μM). antitumor agent-54 inhibits several typical human hepatocellular carcinoma cell lines. antitumor agent-54 blocks the cell cycle in the G1-S phase and induces apoptosis, showing good metabolic stability. It exhibits good metabolic stability.
价 格：￥电议型 号：T62835产 地：中国大陆
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T62834SARS-CoV-2-IN-22；化合物 SARS-CoV-2-IN-22SARS-CoV-2-IN-22
SARS-CoV-2-IN-22 is a SARS-CoV-2 pseudovirus inhibitor (IC50: 16.96 μM).
价 格：￥电议型 号：T62834产 地：中国大陆
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T62833Myoferlin inhibitor 1；化合物 Myoferlin inhibitor 1Myoferlin inhibitor 1
Myoferlin inhibitor 1 is a novel anti-metastatic agent against pancreatic cancer that acts on myosin.
价 格：￥电议型 号：T62833产 地：中国大陆
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T62832FXIa-IN-7；化合物 FXIa-IN-7FXIa-IN-7
FXIa-IN-7 is an orally active, selective factor Xia inhibitor (IC50: 0.4 nM).
价 格：￥电议型 号：T62832产 地：中国大陆
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T62831AD012；化合物 AD012AD012
AD012 is a dual inhibitor of cACE/NEP. AD012 utilises the previously reported C-domain selective ACE inhibitor lenopril-tryptophan synthesis. AD012 has the potential to provide potent anti-hypertensive and cardioprotective effects.
价 格：￥电议型 号：T62831产 地：中国大陆
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T62830SGLT1/2-IN-1；化合物 SGLT1/2-IN-1SGLT1/2-IN-1
SGLT1/2-IN-1 is a dual SGLT1/SGLT2 inhibitor.
价 格：￥电议型 号：T62830产 地：中国大陆
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T6283Wortmannin；渥曼青霉素SL-2052|||KY-12420；SL-2052|||渥曼青霉素|||KY-12420
Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible. Wortmannin is also an inhibitor of PlK1 and PlK3 (IC50=5.8/48 nM) that blocks autophagy.
价 格：￥电议型 号：T6283产 地：中国大陆
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T62829SARS-CoV-2 nsp14-IN-1；化合物 SARS-CoV-2 nsp14-IN-1SARS-CoV-2 nsp14-IN-1
SARS-CoV-2 nsp14-IN-1 (Compound 3) is a typical dual-substrate inhibitor of SARS-CoV-2Nsp14 Mtase (IC50: 0.061 μM). Histone lysine, protein arginine, DNA and RNA, etc.).
价 格：￥电议型 号：T62829产 地：中国大陆
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T62828FRα-IN-1；化合物 FRα-IN-1FRα-IN-1
FRα-IN-1 (Compound 4) is a tumour targeting agent. FRα-IN-1 exhibits selective anti-cancer effects on FRα and FRβ expressing cells.
价 格：￥电议型 号：T62828产 地：中国大陆
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T62827BCP-T.A；化合物 BCP-T.ABCP-T.A
BCP-T.A is a heterocyclic electrophile that binds GPX4 and thus effectively induces iron death (ferroptosis).
价 格：￥电议型 号：T62827产 地：中国大陆
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T62826HOIPIN-8；化合物 HOIPIN-8HOIPIN-8
HOIPIN-8 is a potent inhibitor of the linear ubiquitin chain assembly complex (LUBAC) (IC50: 11 nM). HOIPIN-8 is a derivative of HOIPIN-1 and inhibits petit-LUBAC 255-fold more than HOIPIN-1 and inhibits LUBAC and TNF-α-mediated NF-κB activation 255-fold more than HOIPIN-1. HOIPIN-8 is a promising tool to explore the cellular functions of LUBAC.
价 格：￥电议型 号：T62826产 地：中国大陆
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T62825URAT1 inhibitor 2；化合物 URAT1 inhibitor 2URAT1 inhibitor 2
URAT1 inhibitor 2 is an orally active inhibitor of URAT1 and CYP isozyme with IC50 values of 1.36 μM, 16.97 μM and 5.22 μM for URAT1-mediated 14C-UA uptake, CYP1A2 and CYP2C9, respectively, URAT1 inhibitor 2 is a promising drug candidate for the study of hyperuricemia and gout.
价 格：￥电议型 号：T62825产 地：中国大陆
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T62824FLT3/ITD-IN-3；化合物 FLT3/ITD-IN-3FLT3/ITD-IN-3
FLT3/ITD-IN-3 (Compound 19) is a potent inhibitor of FLT3-ITD, acting on FLT3D835Y (IC50: 0.3 nM), FLT3 (IC50: 0.4 nM) and FLT3-ITD (IC50: 0.9 nM). FLT3/ITD-IN-3 showed potent inhibition of FLT3 phosphorylation and was effective against the proliferation of AML cells.
价 格：￥电议型 号：T62824产 地：中国大陆
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T62823Antifungal agent 39；化合物 Antifungal agent 39Antifungal agent 39
Antifungal agent 39 (Compound 9h) is a broad-spectrum antifungal agent.
价 格：￥电议型 号：T62823产 地：中国大陆
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T62822CT1-3；化合物 CT1-3CT1-3
CT1-3 is a potent anti-cancer agent. CT1-3 regulates the JNK/Bcl-2/Bax/XIAP pathway, which induces mitochondria-mediated apoptosis. CT1-3 regulates the E-cadherin/Snail axis to inhibit epithelial mesenchymal transition (EMT) potentials in human cancer cells (HCCs) and suppresses tumourigenesis. CT1-3 has anti-tumour effects in mouse models and does not show significant hepatotoxicity or nephrotoxicity.
价 格：￥电议型 号：T62822产 地：中国大陆
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T62821Cadisegliatin；化合物 CadisegliatinCadisegliatin
Cadisegliatin (TTP-399) is a potential activator of liver-selective glucose kinase (GK) with hypoglycaemic effects and can be used in the study of type 2 diabetes.
价 格：￥电议型 号：T62821产 地：中国大陆
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T62820OPN expression inhibitor 1；化合物 OPN expression inhibitor 1OPN expression inhibitor 1
OPN expression inhibitor 1 (Compound 11) is an osteopontin (OPN) expression inhibitor that can be used to study breast cancer.
价 格：￥电议型 号：T62820产 地：中国大陆
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T6282GSK461364；化合物GSK461364GSK461364A；GSK461364A
GSK461364 (GSK461364A)(Ki=2.2 nM) inhibits purified Plk1 .The specificity of GSK461364 for Plk1 is more than 1000-fold over Plk2/3.
价 格：￥电议型 号：T6282产 地：中国大陆
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T62819SARS-CoV-2 nsp14-IN-2；化合物 SARS-CoV-2 nsp14-IN-2SARS-CoV-2 nsp14-IN-2
SARS-CoV-2 nsp14-IN-2 is a potent inhibitor of SARS-CoV-2 Nsp14 methyltransferase (IC50: 0.093 μM). SARS-CoV-2 nsp14-IN-2 has the potential to be used in COVID-19 studies.
价 格：￥电议型 号：T62819产 地：中国大陆
