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T62818LSD1/ER-IN-1；化合物 LSD1/ER-IN-1LSD1/ER-IN-1
LSD1/ER-IN-1 (compound 11g) is a potent inhibitor of ER and LSD1 that acts on LSD1 (IC50: 1.55 μM). LSD1/ER-IN-1 showed good anti-proliferative effect on MCF-7 breast cancer cells (IC50: 8.79 μM).
价 格：￥电议型 号：T62818产 地：中国大陆
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T62817Fenticonazole；化合物 FenticonazoleFenticonazole
Fenticonazole is an imidazole derivative with antibacterial and antifungal effects. fenticonazole has potential for mixed vaginitis studies.
价 格：￥电议型 号：T62817产 地：中国大陆
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T62816NVP-CLR457；化合物 NVP-CLR457NVP-CLR457
NVP-CLR457 (compound 40) is an orally active, balanced, pan-class I PI3K inhibitor with antitumour effects.NVP-CLR457 exhibits a significant dose-dependent PK/PD/efficacy relationship.
价 格：￥电议型 号：T62816产 地：中国大陆
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T62815PRMT5-IN-1 hydrochloride；化合物 PRMT5-IN-1 hydrochloridePRMT5-IN-1 hydrochloride
PRMT5 IN-1 hydrochloride (compound 9) is a hemiacetalamine, a potent inhibitor of the selective protein arginine methyltransferase 5 (PRMT5) with an inhibitory effect on PRMT5/MEP50 (IC50: 11 nM). PRMT5 IN-1 hydrochloride can be converted to an aldehyde under physiological conditions and reacts with C449 to form a covalent adduct.
价 格：￥电议型 号：T62815产 地：中国大陆
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T62814Antitumor agent-77；化合物 Antitumor agent-77Antitumor agent-77
Antitumor agent-77 inhibits the growth and migration of cancer cells and has anticancer effects. antitumor agent-77 inhibits GPx-4 and enhances COX2-induced iron sagging. antitumor agent-77 activates the intrinsic apoptotic pathway (Bax-Bcl-2-caspase-3) in tumor cells and prevents tumor cell epithelialization. Antitumor agent-77 activates the tumour cell intrinsic apoptotic pathway (Bax-Bcl-2-caspase-3) and blocks the epithelial mesenchymal transition (EMT) process.
价 格：￥电议型 号：T62814产 地：中国大陆
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T62813JAK3/BTK-IN-6；化合物 JAK3/BTK-IN-6JAK3/BTK-IN-6
JAK3/BTK-IN-6 is a potent dual inhibitor of BTK (IC50: 0.6 nM) and JAK3 (IC50: 0.4 nM).JAK3/BTK-IN-6 exhibits good metabolic stability in human liver microsomes.JAK3/BTK-IN-6 can be used to study blood and immune diseases.
价 格：￥电议型 号：T62813产 地：中国大陆
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T62812RdRP-IN-4；化合物 RdRP-IN-4RdRP-IN-4
RdRP-IN-4 (compound 11q) is an arylbenzohydrazide analogue, an orally active inhibitor of influenza A virus RNA-dependent RNA polymerase (RdRp) that directly binds the PB1 subunit of RdRp. RdRP-IN-4 inhibited H1N1 (A/PR/8/34) Flu A and Flu B strains (B/Lee/1940) in a dose-dependent manner with EC50 values of 53 nM and 20 nM, respectively. RdRP-IN-4 had a significant antiviral effect in infected mice.
价 格：￥电议型 号：T62812产 地：中国大陆
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T62810ZL-Pin13；化合物 ZL-Pin13ZL-Pin13
ZL-Pin13 is a potent covalent inhibitor of cellular activity that selectively acts on Pin1 (IC50: 67 nM). ZL-Pin13 effectively inhibits the proliferation of MDA-MB-231 cells and downregulates Pin1 substrates.
价 格：￥电议型 号：T62810产 地：中国大陆
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T6281TW-37；化合物TW37TW 37；TW 37
TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM).
价 格：￥电议型 号：T6281产 地：中国大陆
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T62809NLRP3-IN-7；化合物 NLRP3-IN-7NLRP3-IN-7
NLRP3-IN-7 (Compound 36) is a selective inhibitor of the NLRP3 inflammasome and is able to assemble the NLRP3 inflammasome.
价 格：￥电议型 号：T62809产 地：中国大陆
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T62808NLRP3-IN-6；化合物 NLRP3-IN-6NLRP3-IN-6
NLRP3-IN-6 (Compound 34) is a selective inhibitor of the NLRP3 inflammasome.
价 格：￥电议型 号：T62808产 地：中国大陆
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T62807AKT-IN-7；化合物 AKT-IN-7AKT-IN-7
AKT-IN-7 (compound 1-P1) is a potent inhibitor of AKT. AKT-IN-7 has potential for cancer research.
价 格：￥电议型 号：T62807产 地：中国大陆
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T62806Trk-IN-9；化合物 Trk-IN-9Trk-IN-9
Trk-IN-9 (Compound 12) is a potent inhibitor of TRK. trk-IN-9 inhibits the proliferation of Km-12 cell lines. trk-IN-9 induces apoptosis in a concentration-dependent manner. trk-IN-9 inhibits TRK phosphorylation and blocks downstream pathways. trk-IN-9 has potential for Trk-IN-9 has potential for NTRK fusion cancer research.
价 格：￥电议型 号：T62806产 地：中国大陆
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T62805SB-612111 hydrochloride；化合物 SB-612111 hydrochlorideSB-612111 hydrochloride
SB-612111 hydrochloride is a potent, novel orphan receptor for opioid receptors (ORL-1) antagonist with high affinity for hORL-1 and a Ki value of 0.33 nM. SB-612111 hydrochloride is able to act on mu-receptor (Ki: 57.6 nM), κ SB-612111 hydrochloride effectively antagonized the nociceptive effects of Nociceptin in an acute pain model.
价 格：￥电议型 号：T62805产 地：中国大陆
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T62804YQ456；化合物 YQ456YQ456
YQ456 is a novel small molecule inhibitor of myosin that binds myosin with high affinity (KD: 37 nM) and is highly resistant to invasion (IC50: 110 nM).
价 格：￥电议型 号：T62804产 地：中国大陆
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T62803STAT3-IN-12；化合物 STAT3-IN-12STAT3-IN-12
STAT3-IN-12 is a potent inhibitor of STAT3 signalling and inhibits IL-6-induced activation of the JAK/STAT3 signalling pathway. STAT3-IN-12 inhibits the growth and migration of cancer cells, blocks the cell cycle and induces apoptosis. HCC), oesophageal cancer.)
价 格：￥电议型 号：T62803产 地：中国大陆
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T62802Indoluidin E；化合物 Indoluidin EIndoluidin E
Indoluidin E selectively inhibits DHODH and has an inhibitory effect on cancer cell growth.
价 格：￥电议型 号：T62802产 地：中国大陆
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T62801FLT3/TrKA-IN-1；化合物 FLT3/TrKA-IN-1FLT3/TrKA-IN-1
FLT3/TrKA-IN-1 is a potent FLT3/TrKA dual kinase inhibitor, capable of acting on FLT3 (IC50: 43.8 nM), FLT3-ITD (IC50: 97.2 nM), FLT3-TKD (IC50: 92.5 nM) and TrKA (IC50: 23.6 nM). -FLT3/TrKA-IN-1 has potential for acute myeloid leukaemia (AML) studies.
价 格：￥电议型 号：T62801产 地：中国大陆
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T62800HPK1-IN-16；化合物 HPK1-IN-16HPK1-IN-16
HPK1-IN-16 is a selective and potent inhibitor of HPK1. HPK1-IN-16 can be used for the study, prevention or amelioration of diseases or conditions associated with HPK1 activity, such as cancer.
价 格：￥电议型 号：T62800产 地：中国大陆
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T6280Enzastaurin；恩扎妥林LY317615；LY317615|||恩扎妥林
Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.
价 格：￥电议型 号：T6280产 地：中国大陆
