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T62745AMPK-IN-3;AMPK抑制剂3AMPK-IN-3
AMPK-IN-3 is a novel, selective and potent AMPK inhibitor with inhibitory effects on AMPK (α2), AMPK (α1) and KDR, with IC50 values of 60.7, 107 and 3820 nM, respectively.AMPK-IN-3 showed anticancer activity in K562 cells.
价 格:¥电议型 号:T62745产 地:中国大陆
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T62744LpxC-IN-9;化合物 LpxC-IN-9LpxC-IN-9
LpxC-IN-9 (compound 19) is a potent inhibitor of LpxC and exhibits antibacterial and hypotensive activity.
价 格:¥电议型 号:T62744产 地:中国大陆
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T62743AChE-IN-10;化合物 AChE-IN-10AChE-IN-10
AChE-IN-10 (Compound 24r) is a potent inhibitor of AChE with an IC50 value of 2.4 nM. AChE-IN-10 decreases amyloid aggregation in the presence of AChE. AChE-IN-10 exhibited a potent inhibitory effect on AChE, reducing tau phosphorylation of S396 residues, rescuing neuronal morphology and increasing cell viability, thereby providing neuroprotection.
价 格:¥电议型 号:T62743产 地:中国大陆
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T62742HPK1-IN-11;化合物 HPK1-IN-11HPK1-IN-11
HPK1-IN-11 is a potent HPK1 inhibitor. HPK1-IN-11 has potential for the study of HPK1-related diseases.
价 格:¥电议型 号:T62742产 地:中国大陆
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T62741DprE1-IN-1;化合物 DprE1-IN-1DprE1-IN-1
DprE1-IN-1 is a potent, orally active DprE1 inhibitor that exhibits good hepatocyte stability, low cytotoxicity and low hERG channel inhibition. DprE1-IN-1 has good anti-branched bacilli activity in macrophages, reducing 1.29 log10 CFU.
价 格:¥电议型 号:T62741产 地:中国大陆
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T62740Antibacterial agent 110;化合物 Antibacterial agent 110Antibacterial agent 110
Antibacterial agent 110 (Compound 4e) is a potent antibacterial agent that acts on P. aeruginosa (MIC: 1 μg/ml). Antibacterial agent 110 disrupts cell membranes and has good antibacterial membrane action.
价 格:¥电议型 号:T62740产 地:中国大陆
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T6274RO4929097;化合物RO4929097RG-4733;RG-4733
RO4929097 (RG-4733), a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).
价 格:¥电议型 号:T6274产 地:中国大陆
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T62739Chitin synthase inhibitor 9;化合物 Chitin synthase inhibitor 9Chitin synthase inhibitor 9
Chitin synthase inhibitor 9 is a chitin synthase (CHS) inhibitor that exhibits broad-spectrum antifungal activity and can be used in studies of fungal infections.
价 格:¥电议型 号:T62739产 地:中国大陆
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T62738Chitin synthase inhibitor 6;化合物 Chitin synthase inhibitor 6Chitin synthase inhibitor 6
Chitin synthase inhibitor 6 (compound 9b) is a potent inhibitor of chitin synthase (CHS) (IC50: 0.21 mM). chitin synthase inhibitor 6 exhibits broad-spectrum antifungal effects against drug-resistant fungi and can be used to study fungal infections.
价 格:¥电议型 号:T62738产 地:中国大陆
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T62737KRAS inhibitor-15;化合物 KRAS inhibitor-15KRAS inhibitor-15
KRAS inhibitor-15 (compound 3-19) is a potent inhibitor of KRAS G12C (IC50: 0.954 μM). KRAS inhibitor-15 exhibits p-ERK inhibition in MIA PaCA-2, A549 cells with IC50s of 2.03, >33.3 μM, respectively. KRAS inhibitor-15 has potential to be studied in pancreatic, colorectal and lung cancers.
价 格:¥电议型 号:T62737产 地:中国大陆
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T62736Cas9-IN-1;化合物 Cas9-IN-1Cas9-IN-1
Cas9-IN-1 is a potent inhibitor of Cas9 with an IC50 value of 7.02 μM. Cas9-IN-1 acts by binding apo-Cas9 and blocking the formation of the Cas9:gRNA complex.
价 格:¥电议型 号:T62736产 地:中国大陆
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T62735GDC-0575 dihydrochloride;化合物 GDC-0575 dihydrochlorideGDC-0575 dihydrochloride
GDC-0575 dihydrochloride (ARRY-575 dihydrochloride) is a selective, orally active CHK1 inhibitor (IC50: 1.2 nM) that exhibits antitumour effects.
价 格:¥电议型 号:T62735产 地:中国大陆
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T62734SARS-CoV-2 3CLpro-IN-4;化合物 SARS-CoV-2 3CLpro-IN-4SARS-CoV-2 3CLpro-IN-4
SARS-CoV-2 3CLpro-IN-4 (Compound 5g) is a multifunctional inhibitor of SARS CoV-2 3CLpro, exhibiting antiviral, antibacterial, and antifungal activities.
价 格:¥电议型 号:T62734产 地:中国大陆
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T62732S1P1 agonist 5;化合物 S1P1 agonist 5S1P1 agonist 5
S1P1 agonist 5 is a selective, orally active S1P1 agonist. S1P1 agonist 5 inhibits the drainage of lymphocytes from lymphoid tissue into peripheral blood. S1P1 agonist 5 has potential for studies in multiple sclerosis (MS).
价 格:¥电议型 号:T62732产 地:中国大陆
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T62731ZK824190 hydrochloride;化合物 ZK824190 hydrochlorideZK824190 hydrochloride
ZK824190 hydrochloride is a selective, orally active urokinase-type fibrinogen activator (uPA) inhibitor that acts on uPA (IC50: 237 nM), tPA (IC50: 1600 nM) and Plasmin (IC50: 1850 nM). hydrochloride can be used in studies of multiple sclerosis
价 格:¥电议型 号:T62731产 地:中国大陆
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T62730TDRL-X80;化合物 TDRL-X80TDRL-X80
TDRL-X80 is a potent inhibitor of the pigmented dry skin protein (XPA). TDRL-X80 inhibits the DNA binding activity of XPA. TDRL-X80 acts on single, double and cisplatin damaged DNA with IC50 values of 18, 20 and 29 μM in fluorescence polarization (FP) assays and 21, 39 and 28 in ELISA assays, 39 and 28.
价 格:¥电议型 号:T62730产 地:中国大陆
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T6273Vadimezan;伐地美生DMXAA|||5,6-Dimethylxanthenone-4-acetic Acid|||NSC 640488|||ASA-404;DMXAA|||伐地美生|||5,6
Vadimezan (DMXAA) is a vascular disrupting agent, a murine STING agonist, and an inducer of cytokines such as type I IFN. Vadimezan has antitumor activity and induces a rapid cessation of blood flow in tumors without affecting blood flow in normal tissues.
价 格:¥电议型 号:T6273产 地:中国大陆
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T62728AChE-IN-24;化合物 AChE-IN-24AChE-IN-24
AChE-IN-24 is a potent inhibitor of AChE that crosses the blood-brain barrier. hAChE is strongly inhibited by AChE-IN-24 (IC50: 0.053 μM). aChE-IN-24 can be used to study Alzheimer´s disease (AD).
价 格:¥电议型 号:T62728产 地:中国大陆
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T62727NRP1 antagonist 1;化合物 NRP1 antagonist 1NRP1 antagonist 1
NRP1 antagonist 1 (compound 12a) is a potent antagonist of NRP1 (IC50: 19.1 μM).
价 格:¥电议型 号:T62727产 地:中国大陆
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T62726Phenylpyropene C;化合物 Phenylpyropene CPhenylpyropene C
Phenylpyropene C (S14-95) is a JAK/STAT pathway inhibitor that exhibits inhibition of IFN-γ-mediated reporter gene expression (IC50: 5.4-10.8 μM) and is also an inhibitor of acyl coenzyme A (IC50: 16.0 μM).
价 格:¥电议型 号:T62726产 地:中国大陆