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  • T62706RTI-7470-44；化合物 RTI-7470-44RTI-7470-44

    RTI-7470-44 is a potent and selective human trace amine-associated receptor 1 (hTAAR1) antagonist (IC50: 8.4 nM) that crosses the blood-brain barrier. RTI-7470-44 increases the spontaneous firing rate of dopaminergic neurons in the ventral tegmental area (VTA) of the midbrain in mice. RTI-7470-44 can be used to study schizophrenia, drug addiction and Parkinson´s disease (PD).

    价 格：￥电议型 号：T62706产 地：中国大陆

  • T62705NSD2-IN-1；化合物 NSD2-IN-1NSD2-IN-1

    NSD2-IN-1 (compound 38) serves as a potent and highly selective inhibitor of NSD2-PWWP1 (nuclear receptor-binding SET domain 2-PWWP1), demonstrating an IC50 value of 0.11 μM. By binding to NSD2-PWWP1, NSD2-IN-1 impacts the expression of genes under NSD2 regulation, leading to apoptosis and cell cycle arrest [1].

    价 格：￥电议型 号：T62705产 地：中国大陆

  • T62704HBV-IN-23；化合物 HBV-IN-23HBV-IN-23

    HBV-IN-23 (Compound 5k) is an inhibitor of HBV DNA replication (IC50: 0.58 μM). HBV-IN-23 inhibits drug-sensitive and drug-resistant strains. HBV-IN-23 induces apoptosis in HepG2 cells and exhibits anti-hepatocellular carcinoma (HCC) effects.

    价 格：￥电议型 号：T62704产 地：中国大陆

  • T62703NTPDase-IN-2；化合物 NTPDase-IN-2NTPDase-IN-2

    NTPDase-IN-2 (compound 5g) selectively inhibits NTPDase-2 and NTPDase-8 with IC50 values of 0.04 ?M and 2.27 ?M, respectively, and exhibits non-competitive inhibition towards h-NTPDase-1 and h-NTPDase-2, with a Km of 74 ?M for h-NTPDase-2. This compound is applicable in researching cancer, immunological disorders, and bacterial infections [1].

    价 格：￥电议型 号：T62703产 地：中国大陆

  • T62702Senexin C；化合物 Senexin CSenexin C

    Senexin C is a novel orally active and specific CDK8/19 inhibitor with potential anticancer activity.Senexin C is more metabolically stable and potent than Senexin B. Senexin C inhibits the growth of MV4-11 leukaemia cells.

    价 格：￥电议型 号：T62702产 地：中国大陆

  • T62701Dihydropteroate synthase-IN-1；化合物 Dihydropteroate synthase-IN-1Dihydropteroate synthase-IN-1

    Dihydropteroate synthase-IN-1 (compound 5g) is a potent inhibitor of dihydropteroate synthase (DHPS) with inhibitory effects on cytochrome P450. Dihydropteroate synthase-IN-1 can be used as a diagnostic radiographic material.

    价 格：￥电议型 号：T62701产 地：中国大陆

  • T62700CBP/p300-IN-16；化合物 CBP/p300-IN-16CBP/p300-IN-16

    CBP/p300-IN-16 (compound 1) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.61 μM) and LK2 H3K27 (IC50: 2.24 μM).

    价 格：￥电议型 号：T62700产 地：中国大陆

  • T6270Trichostatin A；曲古抑菌素ATSA；曲古柳菌素A|||曲古抑菌素A|||TSA

    Trichostatin A (TSA) is a natural derivative of diene isohydroxamic acids. Trichostatin A is a histone deacetylase inhibitor (IC50=1.8 nM) that is reversible and specific. Trichostatin A leads to the hyperacetylation of core histones, which regulates chromatin structure.

    价 格：￥电议型 号：T6270产 地：中国大陆

  • T62699Glyoxalase I inhibitor 2；化合物 Glyoxalase I inhibitor 2Glyoxalase I inhibitor 2

    Glyoxalase I inhibitor 2 (compound 26) is a potent inhibitor of glyoxalase I (GLO1) (IC50: 0.5 μM). Glyoxalase I inhibitor 2 has potential for depression and anxiety studies.

    价 格：￥电议型 号：T62699产 地：中国大陆

  • T62697BuChE-IN-3；化合物 BuChE-IN-3BuChE-IN-3

    BuChE-IN-3 (Compound C4) is a potent inhibitor of BuChE (IC50: 8.3 nM). buChE-IN-3 is a mild antioxidant, non-toxic, lipophilic and neuroprotective agent.

    价 格：￥电议型 号：T62697产 地：中国大陆

  • T62695GFB-12811；化合物 GFB-12811GFB-12811

    GFB-12811 is a highly selective and orally active inhibitor of cyclin-dependent kinase 5 (CDK5), exhibiting an inhibitory concentration (IC50) of 2.3 nM. It demonstrates notable specificity, with minimal activity against other tested kinases, including CDK1, CDK2, CDK6, CDK7, and CDK9 [1].

    价 格：￥电议型 号：T62695产 地：中国大陆

  • T62694(S)-GFB-12811；化合物 (S)-GFB-12811(S)-GFB-12811

    (S)-GFB-12811 (compound 596) is a selective and selective inhibitor of CDK5 (IC50<10 nM). (S)-GFB-12811 can be used in studies of cell cycle progression, neuronal development, and tumorigenesis.

    价 格：￥电议型 号：T62694产 地：中国大陆

  • T62693Tubulin polymerization-IN-29；化合物 Tubulin polymerization-IN-29Tubulin polymerization-IN-29

    Tubulin polymerization-IN-29 is a potent inhibitor of microtubule protein polymerization and shows potent anti-proliferative effects.Tubulin polymerization-IN-29 induces cell cycle arrest in HeLa cells at G2/M phase.

    价 格：￥电议型 号：T62693产 地：中国大陆

  • T62692ML-SI1；化合物 ML-SI1ML-SI1

    ML-SI1, a racemic mixture of diastereoisomers, is a TRPML inhibitor and acts on TRPML1 (IC50: 15 μM).

    价 格：￥电议型 号：T62692产 地：中国大陆

  • T62691Syk Inhibitor II dihydrochloride dihydrate；化合物 Syk Inhibitor II dihydrochloride dihydrateSyk Inhibit

    Syk Inhibitor II dihydrochloride dihydrate is a highly selective, potent, ATP-competitive Syk inhibitor (IC50: 41 nM). Syk Inhibitor II dihydrochloride dihydrate exhibits anti-allergic effects.

    价 格：￥电议型 号：T62691产 地：中国大陆

  • T62690HIV-1 inhibitor-46；化合物 HIV-1 inhibitor-46HIV-1 inhibitor-46

    HIV-1 inhibitor-46 (compound 13d) is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase (EC50: 1.425 μM). HIV-1 inhibitor-46 can be used in the study of AIDS.

    价 格：￥电议型 号：T62690产 地：中国大陆

  • T6269Bemcentinib；化合物BemcentinibR428|||BGB324；R428|||BGB324

    Bemcentinib (R428) is a selective inhibitor of Axl (IC50: 14 nM) and has been investigated for the treatment of NSCLC.

    价 格：￥电议型 号：T6269产 地：中国大陆

  • T62689Factor B-IN-5；化合物 Factor B-IN-5Factor B-IN-5

    Factor B-IN-5 is a potent inhibitor (IC50: 1.2 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases.

    价 格：￥电议型 号：T62689产 地：中国大陆

  • T62688Factor B-IN-4；化合物 Factor B-IN-4Factor B-IN-4

    Factor B-IN-4 is a potent inhibitor (IC50: 1 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases.

    价 格：￥电议型 号：T62688产 地：中国大陆

  • T62687Drp1-IN-1；化合物 Drp1-IN-1Drp1-IN-1

    Drp1-IN-1 (comp A-7) is a Drp1 protein inhibitor (IC50: 0.91 μM).

    价 格：￥电议型 号：T62687产 地：中国大陆

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