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T62648DNA-PK-IN-1;化合物 DNA-PK-IN-1DNA-PK-IN-1
DNA-PK-IN-1 is a potent inhibitor of DNA-PK. DNA-PK-IN-1 has potential for cancer disease research.
价 格:¥电议型 号:T62648产 地:中国大陆
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T62647Aurora A inhibitor 2;化合物 Aurora A inhibitor 2Aurora A inhibitor 2
Aurora A inhibitor 2 (Compound 16h) is a potent inhibitor of Aurora A kinase (IC50: 21.94 nM).
价 格:¥电议型 号:T62647产 地:中国大陆
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T62646Pparδ agonist 5;化合物 Pparδ agonist 5Pparδ agonist 5
Pparδ agonist 5 is a selective, orally active PPARδ agonist with an EC50 of 0.335 μM and better selectivity than GW0742. Pparδ agonist 5 has a beneficial effect on the improvement of bone density and microarchitecture in vivo.
价 格:¥电议型 号:T62646产 地:中国大陆
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T62645HPK1-IN-14;化合物 HPK1-IN-14HPK1-IN-14
HPK1-IN-14 is a potent inhibitor of HPK1. HPK1-IN-14 has potential for the study of HPK1-related diseases.
价 格:¥电议型 号:T62645产 地:中国大陆
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T62644HDAC-IN-41;化合物 HDAC-IN-41HDAC-IN-41
HDAC-IN-41 (Compound 7c) is an orally active, selective class I HDAC inhibitor that acts on HDAC1 (IC50: 0.62 μM), HDAC2 (IC50: 1.46 μM) and HDAC3 (IC50: 0.62 μM). HDAC-IN-41 shows NO-releasing activity.
价 格:¥电议型 号:T62644产 地:中国大陆
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T62643DY-46-2;化合物 DY-46-2DY-46-2
DY-46-2 is a highly selective, potent, novel non-nucleoside DNA methyltransferase 3A (DNMT3A) inhibitor (IC50: 1.3 μM).
价 格:¥电议型 号:T62643产 地:中国大陆
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T62642Microtubule inhibitor 4;化合物 Microtubule inhibitor 4Microtubule inhibitor 4
Microtubule inhibitor 4 (compound 2) is a potent inhibitor of microtubule and inhibits microtubule protein polymerization, HT-29 cells (IC50: 2.1 nM) exhibited cytotoxicity.
价 格:¥电议型 号:T62642产 地:中国大陆
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T62641EP2 receptor antagonist-1;化合物 EP2 receptor antagonist-1EP2 receptor antagonist-1
EP2 receptor antagonist-1 is a reversible, potent, agonist-dependent variant of the prostaglandin EP2 receptor antagonist.EP2 receptor antagonist-1 exhibits anti-inflammatory activity.
价 格:¥电议型 号:T62641产 地:中国大陆
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T62640FPR2 agonist 2;化合物 FPR2 agonist 2FPR2 agonist 2
FPR2 agonist 2 is a potent FPR2 agonist with blood-brain barrier permeability that acts on h-FPR2 (EC50: 0.13 nM). fPR2 agonist 2 inhibits the production of pro-inflammatory cytokines, counteracts changes in mitochondrial function, and inhibits caspase-3 activity.
价 格:¥电议型 号:T62640产 地:中国大陆
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T6264Bosentan;波生坦Actelion|||Ro 47-0203|||Benzenesulfonamide;Actelion|||波生坦|||Ro 47-0203|||Benzenesulfonam
Bosentan (Benzenesulfonamide) is a sulfonamide-derived, competitive and specific endothelin receptor antagonist with a slightly higher affinity for the endothelin A receptor than endothelin B receptor. Bosentan blocks the action of endothelin 1, an extremely potent endogenous vasoconstrictor and bronchoconstrictor, by binding to endothelin A and endothelin B receptors in the endothelium and vascular smooth muscle. Bosentan decreases both pulmonary and systemic vascular resistance and is particul
价 格:¥电议型 号:T6264产 地:中国大陆
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T62639Microtubule inhibitor 7;化合物 Microtubule inhibitor 7Microtubule inhibitor 7
Compounds 17o (IC50= 14.0 nM, NCI-H460) and 17p (IC50= 2.9 nM, NCI-H460) with furan moieties show potent nanomolar levels of cytotoxic activity against various human cancer cell lines.
价 格:¥电议型 号:T62639产 地:中国大陆
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T62638IDO1-IN-18;化合物 IDO1-IN-18IDO1-IN-18
IDO1-IN-18 (Compound 14) is a potent inhibitor of IDO1. IDO1-IN-18 has potential for cancer disease research.
价 格:¥电议型 号:T62638产 地:中国大陆
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T62637EIF2α activator 2;化合物 EIF2α activator 2EIF2α activator 2
EIF2α activator 2 (Compound 1) is a phosphorylated activator of eukaryotic initiation factor 2α (eIF2α). EIF2α activator 2 is anti-proliferative in K562 cells (IC50: 4.79 μM) and PBMC cells (IC50: 10.52 μM).
价 格:¥电议型 号:T62637产 地:中国大陆
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T62636MsbA-IN-1;化合物 MsbA-IN-1MsbA-IN-1
MsbA-IN-1 is a potent inhibitor of MsbA (IC50: 4 nM). MsbA-IN-1 has anti-E. coli activity (MIC: 79 μM). MsbA-IN-1 fully penetrates the outer membrane of Gram-negative bacteria and exhibits inhibition of MsbA.
价 格:¥电议型 号:T62636产 地:中国大陆
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T62635Antifungal agent 30;化合物 Antifungal agent 30Antifungal agent 30
Antifungal agent 30 is a potent antifungal agent that exhibits good antifungal activity against Candida albicans (CPCC400616) (MIC: 0.03 μg/mL) and Aspergillus fumigatus (MIC: 0.5 μg/mL). Antifungal agent 30 exerts antifungal activity through hydrogen and ligand interactions with CYP51.
价 格:¥电议型 号:T62635产 地:中国大陆
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T62634K027;化合物 K027K027
K027 is a potent organophosphate (OP) inhibitor of acetylcholinesterase (AChE) reactivation. k027 can be used to study Alzheimer´s disease.
价 格:¥电议型 号:T62634产 地:中国大陆
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T62633NTPDase-IN-3;化合物 NTPDase-IN-3NTPDase-IN-3
NTPDase-IN-3 (Compound 5e), an inhibitor of NTPDase, exhibits IC50 values of 0.38 μM (NTPDase3), 0.05 μM (NTPDase8), 0.21 μM (NTPDase1), and 1.07 μM (NTPDase2). It is utilized in cancer and thrombosis research [1].
价 格:¥电议型 号:T62633产 地:中国大陆
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T62632HPK1-IN-21;化合物 HPK1-IN-21HPK1-IN-21
HPK1-IN-21 is a potent, orally active HPK1 kinase inhibitor with a Ki value of 0.8 nM.
价 格:¥电议型 号:T62632产 地:中国大陆
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T62631CB2 receptor antagonist 1;化合物 CB2 receptor antagonist 1CB2 receptor antagonist 1
Hexyl resorcinol derivative 29 is a CB2 selective competitive antagonist/reverse agonist demonstrating notable potency. Meanwhile, Olivanol and 5-(2-methyloctane-2-yl) resorcinol derivatives 23 and 24 exhibit substantial antinociceptive effects. Notably, compound 24 activates both cannabinoid and TRPV1 receptors.
价 格:¥电议型 号:T62631产 地:中国大陆
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T62630Posenacaftor;化合物 PosenacaftorPosenacaftor
Posenacaftor (PTI-801) is a cystic fibrosis transmembrane regulatory protein (CFTR) regulator. Posenacaftor corrects the folding and transport of CFTR proteins and can be used to study cystic fibrosis (CF).
价 格:¥电议型 号:T62630产 地:中国大陆