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T6257AZ191；化合物AZ191AZ191
AZ191（IC50 of 17 nM） is an effective and specific DYRK1B inhibitor. The specificity of AZ191 for DYRK1B is about 5- and 110-fold greater over DYRK1A and DYRK2, respectively.
价 格：￥电议型 号：T6257产 地：中国大陆
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T62569RIPK3-IN-2；化合物 RIPK3-IN-2RIPK3-IN-2
RIPK3-IN-2 is a RIP3 inhibitor that can be used in studies of diseases caused by or associated with activated necrotic pathways.
价 格：￥电议型 号：T62569产 地：中国大陆
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T62568IXA6；化合物 IXA6IXA6
IXA6 is a novel IRE1/XBP1s agonist with potential vasoprotective activity that activates IRE1-XBP1s signaling and XBP1s transcriptional response, which can be used to study neurodegenerative diseases such as Parkinson´s disease and Alzheimer´s disease.
价 格：￥电议型 号：T62568产 地：中国大陆
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T62567CDK2-IN-9；化合物 CDK2-IN-9CDK2-IN-9
CDK2-IN-9 is a potent inhibitor of CDK2 (IC50: 0.63 μM) with anti-proliferative effects. CDK2-IN-9 is capable of blocking the cell cycle in S and G2/M phases and inducing apoptosis. CDK2-IN-9 has potential for melanoma research.
价 格：￥电议型 号：T62567产 地：中国大陆
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T62566KRAS G12C inhibitor 53；化合物 KRAS G12C inhibitor 53KRAS G12C inhibitor 53
KRAS G12C inhibitor 53 (Compound 1) is a KRAS G12C inhibitor.
价 格：￥电议型 号：T62566产 地：中国大陆
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T62565BChE-IN-9；化合物 BChE-IN-9BChE-IN-9
BChE-IN-9 (Azepano-11-deoxo-glycyrrhetol) is a hybrid BChE inhibitor (Ki: 0.21 μM).
价 格：￥电议型 号：T62565产 地：中国大陆
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T62564RORγt inverse agonist 30；化合物 RORγt inverse agonist 30RORγt inverse agonist 30
RORγt inverse agonist 30 (Compound 1) is a potent RORγt inverse agonist (IC50: 46 nM). Targeting the nuclear receptor RORγt is effective in the treatment of autoimmune diseases.
价 格：￥电议型 号：T62564产 地：中国大陆
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T62563ATR-IN-12；化合物 ATR-IN-12ATR-IN-12
ATR-IN-12 (Compound 5g) is a potent inhibitor of ataxia capillaris and Rad3-related (ATR) kinase (IC50: 0.007 μM). ATR-IN-12 is a promising lead compound for subsequent drug discovery studies on ATR kinases.
价 格：￥电议型 号：T62563产 地：中国大陆
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T62561TRK-IN-17；化合物 TRK-IN-17TRK-IN-17
TRK-IN-17 is a potent inhibitor of TRK. Among them is promyosin-related kinase (Trks), a member of the receptor tyrosine kinase family, which is activated by neurotrophic factors. Neurotrophic factors are a group of soluble growth factors including nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and neurotrophic factor-3 (NT-3), and neurotrophic factor-4/5 (NT-4/5).TRK-IN-17 has potential for cancer disease research.
价 格：￥电议型 号：T62561产 地：中国大陆
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T62560Sirpiglenastat；化合物SirpiglenastatDRP-104；DRP-104
Sirpiglenastat (DRP-104) is a glutamine antagonist, a prodrug of DON, with antitumor activity that acts by inhibiting glutamine metabolism and stimulating the innate and adaptive immune system.
价 格：￥电议型 号：T62560产 地：中国大陆
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T6256YYA-021；化合物YYA021YYA 021；YYA 021
YYA-021 inhibits HIV entry, with high anti-HIV activity and low cytotoxicity.
价 格：￥电议型 号：T6256产 地：中国大陆
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T62559TGFβRI-IN-4；化合物 TGFβRI-IN-4TGFβRI-IN-4
TGFβRI-IN-4 is a potent, orally active TGFβ receptor type I kinase (TGFβRI) inhibitor that acts on ALK5 (IC50: 44 nM) and NIH3T3 (IC50: 42.5 nM).TGFβRI-IN-4 inhibits tumor growth and tumor weight in a xenograft tumor model.
价 格：￥电议型 号：T62559产 地：中国大陆
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T62558FAAH-IN-5；化合物 FAAH-IN-5FAAH-IN-5
FAAH-IN-5 (Compound 7) is a relatively selective, irreversible inhibitor of fatty acid amide hydrolase (FAAH) (IC50: 10.5 nM). FAAH-IN-5 has low PAMPA (parallel artificial membrane permeability assay) permeability.
价 格：￥电议型 号：T62558产 地：中国大陆
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T62557CSF1R-IN-14；化合物 CSF1R-IN-14CSF1R-IN-14
CSF1R-IN-14, an isoindolinone derivative compound, is a potent inhibitor of CSF1R. CSF1R-IN-14 has potential for cancer disease research.
价 格：￥电议型 号：T62557产 地：中国大陆
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T62556JAK-IN-23；化合物 JAK-IN-23JAK-IN-23
JAK-IN-23 is an orally active dual JAK/STAT and NF-κB inhibitor that inhibits J AK1 (IC50: 8.9 nM), J AK2 (IC50: 15 nM), and J AK3 (IC50: 46.2 nM). JAK-IN-23 exhibits strong anti-inflammatory effects and can reduce the release of various pro-inflammatory factors.JAK-IN-23 can be used to study inflammatory bowel disease (IBD).
价 格：￥电议型 号：T62556产 地：中国大陆
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T62555MMP-2/9-IN-1；化合物 MMP-2/9-IN-1MMP-2/9-IN-1
MMP-2/9-IN-1 (Compound 4a) is a potent dual inhibitor of MMP-2 (IC50: 56 nM) and MMP-9 (IC50: 38 nM). leading to DNA fragmentation.
价 格：￥电议型 号：T62555产 地：中国大陆
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T62554PPARγ phosphorylation inhibitor 1；化合物 PPARγ phosphorylation inhibitor 1PPARγ phosphorylation inhibit
PPARγ phosphorylation inhibitor 1 (Compound 10) is a potent PPARγ binding agent (IC50: 24 nM) with antidiabetic effects. PPARγ phosphorylation inhibitor 1 exhibited inhibition of CDK5-mediated PPARγ Ser273 phosphorylation (IC50: 160 nM) and little PPARγ agonism.
价 格：￥电议型 号：T62554产 地：中国大陆
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T62553JAK3/BTK-IN-4；化合物 JAK3/BTK-IN-4JAK3/BTK-IN-4
JAK3/BTK-IN-4 is a potent inhibitor of JAK3/BTK. BTK and JAK3 are two important targets in autoimmune diseases. Simultaneous inhibition of the BTK/JAK3 signaling pathway has a synergistic effect and JAK3/BTK-IN-4 has potential for JAK3 kinase and/or BTK-related diseases.
价 格：￥电议型 号：T62553产 地：中国大陆
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T62552Ozanimod hydrochloride；Ozanimod 盐酸盐BMS-986374 hydrochloride|||RPC-1063 hydrochloride；BMS-986374 hydr
Ozanimod hydrochloride (RPC-1063 hydrochloride) is an orally available, selective and potent sphingosine 1-phosphate (S1P) receptor modulator that shows high affinity for S1P1 and S1P5.Ozanimod has potential anticancer activity and can be used in the study of multiple sclerosis (MS), ulcerative multiple sclerosis (UMS), and other diseases. (MS), ulcerative colitis, coronavirus infections and myelodysplasia.
价 格：￥电议型 号：T62552产 地：中国大陆
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T62551ANEB-001；化合物 ANEB-001ANEB-001
ANEB-001 is an orally active CB1 inhibitor that can be used in studies of acute cannabinoid intoxication.
价 格：￥电议型 号：T62551产 地：中国大陆
