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T62550DSM705 hydrochloride；化合物 DSM705 hydrochlorideDSM705 hydrochloride
DSM705 hydrochloride is a potent antimalarial compound and a pyrrole-based inhibitor of dihydroorotate dehydrogenase (DHODH).DSM705 hydrochloride shows nanomolar effects against PlasmodiumDHODH and Plasmodium parasites and does not inhibit mammalian DHODH.
价 格：￥电议型 号：T62550产 地：中国大陆
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T6255Bromosporine；化合物BromosporineBromosporine
Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.
价 格：￥电议型 号：T6255产 地：中国大陆
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T62549Antiproliferative agent-7；化合物 Antiproliferative agent-7Antiproliferative agent-7
Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 can promote ROS production and induce apoptosis.
价 格：￥电议型 号：T62549产 地：中国大陆
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T62548ATR-IN-17；化合物 ATR-IN-17ATR-IN-17
ATR-IN-17 is a potent inhibitor of ATR kinase with good anti-cancer effects in LoVo cells (IC50: 1 nM).
价 格：￥电议型 号：T62548产 地：中国大陆
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T62547HPK1-IN-17；化合物 HPK1-IN-17HPK1-IN-17
HPK1-IN-17 is a selective and potent inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPK1) is a member of the MAP4Ks family and was originally cloned from hematopoietic progenitor cells. HPK1-IN-17 can be used to study, prevent or ameliorate diseases or conditions associated with HPK1 activity (e.g., cancer).
价 格：￥电议型 号：T62547产 地：中国大陆
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T62546ALK5-IN-27；化合物 ALK5-IN-27ALK5-IN-27
ALK5-IN-27 (Compound EX-04) is a potent inhibitor of ALK-5 (IC50 ≤ 10 nM). ALK5-IN-27 also inhibits ALK-2.
价 格：￥电议型 号：T62546产 地：中国大陆
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T62545HDAC-IN-43；化合物 HDAC-IN-43HDAC-IN-43
HDAC-IN-43 is a potent HDAC 1/3/6 inhibitor with IC50 values of 82 nM for HDAC 1, 45 nM for HDAC 3, and 24 nM for HDAC 6. HDAC-IN-43 is a weak PI3K/mTOR inhibitor with IC50 values of 3.6 μM for PI3K and 3.7 μM for mTOR. HDAC-IN-43 has a broad-spectrum anti-proliferative effect.
价 格：￥电议型 号：T62545产 地：中国大陆
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T62544MK-8153；化合物 MK-8153MK-8153
MK-8153 is a selective, potent, orally active inhibitor of extrarenal medullary potassium channels (ROMK), acting on ROMK EP (IC50: 5 μM) and hERG EP (IC50: 34 μM).MK-8153 can be used as a diuretic.
价 格：￥电议型 号：T62544产 地：中国大陆
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T62543JNc-440；化合物 JNc-440JNc-440
JNc-440 is a potent anti-hypertensive agent. jNc-440 enhances the interaction between the transient receptor potential vanilloid subtype 4 (TRPV4) and calcium-activated potassium channel 3 (KCa2.3) in endothelial cells. jNc-440 also increases vasodilation and has hypotensive activity in mice.
价 格：￥电议型 号：T62543产 地：中国大陆
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T62542GPR40 agonist 5；化合物 GPR40 agonist 5GPR40 agonist 5
GPR40 agonist 5 is an orally active GPR40 (G protein-coupled receptor 40) agonist (EC50: 47 nM). gPR40 agonist 5 reduces blood glucose levels and improves glucose tolerance. gPR40 agonist 5 shows adequate control of hyperglycemic state in type 2 diabetic mice.
价 格：￥电议型 号：T62542产 地：中国大陆
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T62541AChE-IN-22；化合物 AChE-IN-22AChE-IN-22
AChE-IN-22 (compound 10q) is a selective inhibitor of acetylcholinesterase (AChE) that acts on both AChE (IC50: 0.88 μM) and BuChE (IC50: 10 μM). AChE-IN-22 binds to both the CAS (catalytic active site) and PAS (peripheral anionic site) sites of AChE and can be used to study Alzheimer´s disease.
价 格：￥电议型 号：T62541产 地：中国大陆
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T62540PARP1/BRD4-IN-2；化合物 PARP1/BRD4-IN-2PARP1/BRD4-IN-2
PARP1/BRD4-IN-2 is a potent and selective inhibitor of PARP1 (IC50: 197 nM) and BRD4 (IC50: 238 nM).PARP1/BRD4-IN-2 inhibits DNA damage repair, blocks the G0/G1 cell cycle transition, and induces apoptosis.PARP1/BRD4-IN-2 exhibits antitumor effects in the MDA-MB-468 mouse xenograft tumor model.PARP1/BRD4-IN-2 has been used to study the antitumor effects of PARP1/BRD4-IN-2 in triple-negative breast cancer (MDA-MB-468). PARP1/BRD4-IN-2 exhibits antitumor effects in the MDA-MB-468 mouse xenograft t
价 格：￥电议型 号：T62540产 地：中国大陆
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T6254Idasanutlin；依达奴林RG7388|||Ro 5503781；RG7388|||Ro 5503781|||依达奴林
Idasanutlin (Ro 5503781) (RG-7388) is an effective and specific p53-MDM2 inhibitor (IC50: 6 nM).
价 格：￥电议型 号：T6254产 地：中国大陆
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T62538AChE-IN-15；化合物 AChE-IN-15AChE-IN-15
AChE-IN-15 (Compound 3d) is a reversible inhibitor of human acetylcholinesterase (huAChE) and human butyrylcholinesterase (huBChE) with IC50 values of 6.8 μM and 16.1 μM for huAChE and huBChE, respectively, with significant antioxidant activity. Alzheimer´s disease.
价 格：￥电议型 号：T62538产 地：中国大陆
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T62537Antimalarial agent 7；化合物 Antimalarial agent 7Antimalarial agent 7
Antimalarial agent 7 is a potent and effective inhibitor of PfATP4. Antimalarial agent 7 has potential for the study of the human plasmodium falciparum.
价 格：￥电议型 号：T62537产 地：中国大陆
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T62536S100P-IN-1；S100P抑制剂1S100P-IN-1
S100P-IN-1 is a potent S100P inhibitor.S100P-IN-1 has anti-metastatic effects on pancreatic cancer (pancreatic) cells.
价 格：￥电议型 号：T62536产 地：中国大陆
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T62535ZINC09659342；化合物 ZINC09659342ZINC09659342
ZINC09659342 (compound 13) is an inhibitor of Lbc-RhoA interaction (IC50: 3.6 μM).
价 格：￥电议型 号：T62535产 地：中国大陆
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T62534POP-IN-2；化合物 POP-IN-2POP-IN-2
POP-IN-2 (Compound 7k) is a potent, covalently bound inhibitor of prolyl oligopeptidase (POP) (Ki: 6 nM).POP-IN-2 can be used in neurodegenerative disease and cancer research.
价 格：￥电议型 号：T62534产 地：中国大陆
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T62533MALT1-IN-8；化合物 MALT1-IN-8MALT1-IN-8
MALT1-IN-8 is a potent inhibitor of MALT1 protease (IC50: 2 nM). MALT1-IN-8 inhibits the growth of OCI-LY3 lymphoma cells (IC50: 1.16 μM) and exhibits anticancer activity.
价 格：￥电议型 号：T62533产 地：中国大陆
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T62531TRK-IN-12；化合物 TRK-IN-12TRK-IN-12
TRK-IN-12 (Compound 9e), a macrocyclic derivative, is a potent TRK inhibitor, with efficacy against TRK G595R (IC 50 = 13.1 nM). It demonstrates significant antiproliferative activity in the Ba/F3-LMNA-NTRK1 cell line (IC 50 = 0.080 μM) and exhibits superior inhibitory performance (IC 50 = 0.646 μM) compared to the control agent LOXO-101 in the Ba/F3-LMNA-NTRK1-G595R cell line [1].
价 格：￥电议型 号：T62531产 地：中国大陆
