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T62530N-Arachidonyldopamine;化合物NADANADA;NADA
N-Arachidonyldopamine (NADA) is a selective and potent endogenous CB1 receptor agonist (Ki: 250 nM).N-Arachidonyldopamine is also a potent and selective TRPV1 agonist with an EC50 value of ~50 nM.
价 格:¥电议型 号:T62530产 地:中国大陆
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T6253Talazoparib;他拉唑帕利LT-673|||BMN-673;LT-673|||BMN-673|||他拉唑帕利
Talazoparib (LT-673) is a PARP inhibitor that inhibits PARP 1 and PARP 2 (Ki=1.2/0.87 nM) and is orally active. Talazoparib has anti-tumorigenic activity and induces tumor cell death by blocking PARP enzyme activity and by trapping PARP at DNA damage sites.
价 格:¥电议型 号:T6253产 地:中国大陆
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T62528Dopamine D3 receptor ligand-1;化合物 Dopamine D3?receptor ligand-1Dopamine D3 receptor ligand-1
Dopamine D 3 receptor ligand is a potent, selective, high-affinity dopamine D3 receptor ligand that is 89 times more selective for D3 (Ki: 8 nM) than D2 (Ki: 715 nM).
价 格:¥电议型 号:T62528产 地:中国大陆
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T62527INO-1001;化合物 INO-1001INO-1001
INO-1001 is a potent, selective poly(ADP-ribose) polymerase (PARP) inhibitor with antitumor activity.INO-1001 is a potent radiosensitization enhancer that uses interference with DNA repair mechanisms to enhance radiation-induced cell killing and necrotic cell death.
价 格:¥电议型 号:T62527产 地:中国大陆
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T62526HIV-1 inhibitor-8;化合物 HIV-1 inhibitor-8HIV-1 inhibitor-8
HIV-1 inhibitor-8 is a potent, orally active, low toxicity HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI). HIV-1 inhibitor-8 is capable of acting on WT HIV-1 reverse transcriptase (IC50: 0.081 μM). HIV-1 inhibitor-8 exhibited potent antiviral effects against various HIV-1 strains with EC50 values of 4.44-54.5 nM.
价 格:¥电议型 号:T62526产 地:中国大陆
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T62525TP-16;化合物 TP-16TP-16
TP-16 is a novel potent and selective EP4 antagonist that blocks the function of IMCs and enhances cytotoxic T cell-mediated tumor elimination in vivo.
价 格:¥电议型 号:T62525产 地:中国大陆
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T62524Panobinostat lactate;化合物 Panobinostat lactatePanobinostat lactate
Panobinostat lactate is a potent, orally active, non-selective HDAC inhibitor with antitumor effects. Panobinostat lactate can be used to study refractory or relapsed multiple myeloma.
价 格:¥电议型 号:T62524产 地:中国大陆
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T62523Anticancer agent 40;化合物 Anticancer agent 40Anticancer agent 40
Anticancer agent 40 (compound 3e) is a potent anticancer agent that has anticancer effects on SKBR-3 cells (IC50: 0.94 nM), SKOV-3 cells (IC50: 0.98 nM), PC-3 cells (IC50: 0.96 nM), U-87 cells ), U-87 cells (IC50: 0.95 nM), and HDF cells (IC50: 2.13 nM).
价 格:¥电议型 号:T62523产 地:中国大陆
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T62522FGFR-IN-4;化合物 FGFR-IN-4FGFR-IN-4
FGFR-IN-4 is a potent inhibitor of FGFR. FGFR-IN-4 has potential for cancer disease studies.
价 格:¥电议型 号:T62522产 地:中国大陆
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T62521A2AAR/HDAC-IN-1;化合物 A2AAR/HDAC-IN-1A2AAR/HDAC-IN-1
A2AAR/HDAC-IN-1 (compound 14c) is an orally active, balanced A2AAR/HDAC dual inhibitor of A2AAR (Ki: 163.5 nM), HDAC1 (IC50: 145.3 nM). effect.
价 格:¥电议型 号:T62521产 地:中国大陆
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T62520Imidocarb dihydrochloride monohydrate;化合物 Imidocarb dihydrochloride monohydrateImidocarb dihydrochlo
Imidocarb dihydrochloride monohydrate is an effective antiprotozoal agent against the parasite B. bovis (IC50: 87 μg/ml).
价 格:¥电议型 号:T62520产 地:中国大陆
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T6252Ipatasertib;帕他色替GDC-0068|||RG7440;GDC-0068|||RG7440|||帕他色替
Ipatasertib (GDC-0068) (GDC-0068), a highly specific pan-Akt inhibitor, targets Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM, respectively.
价 格:¥电议型 号:T6252产 地:中国大陆
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T62519SW02;化合物 SW02SW02
SW02 is a potent ATPase activator of Hsp70 (EC50: 150 μM). SW02 is able to accumulate total tau and phosphorylated tau (pTau).
价 格:¥电议型 号:T62519产 地:中国大陆
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T62518GRK6-IN-1;化合物 GRK6-IN-1GRK6-IN-1
GRK6-IN-1 (compound 18) is a potent inhibitor of G protein-coupled receptor kinase 6 (GRK6) (IC50: 120 nM). GRK6-IN-1 has the potential to be studied in multiple myeloma.
价 格:¥电议型 号:T62518产 地:中国大陆
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T62517S1p receptor agonist 2;化合物 S1p receptor agonist 2S1p receptor agonist 2
S1p receptor agonist 2 (compound 1) is an agonist of the S1P5 receptor with a higher selectivity than S1P1 and/or S1P3 receptors.S1p receptor agonist 2 can be used in the endogenous SIP signaling system and in the mitigation/prevention of central nervous system (CNS) diseases such as neurodegenerative diseases. .
价 格:¥电议型 号:T62517产 地:中国大陆
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T62516SV5;化合物 SV5SV5
SV5 is a potent anti-Alzheimer agent. sv5 significantly protects SHSY-5Y cells from Aβ1-42-induced death. sv5 is highly stable and has optimal pharmacological properties in human plasma. sv5 has appropriate antioxidant and good neuroprotective activity.
价 格:¥电议型 号:T62516产 地:中国大陆
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T62515SIRT2-IN-9;化合物SIRT2-IN-9SIRT2-IN-9
SIRT2-IN-9 is a selective SRIT2 inhibitor with an IC50 value of 1.3 μM.SIRT2-IN-9 inhibits the proliferation of MCF-7 breast cancer cells.SIRT2-IN-9 can be used for cancer research.
价 格:¥电议型 号:T62515产 地:中国大陆
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T62514HDAC-IN-46;化合物 HDAC-IN-46HDAC-IN-46
HDAC-IN-46 (compound 12c) is a potent inhibitor of HDAC that acts on HDAC1 (IC50: 0.21 μM) and HDAC6 (IC50: 0.021 μM). HDAC-IN-46 upregulates p-p38 and downregulates Bcl-xL and cyclin D1 in MDA-MB-231 cells. HDAC-IN-46 can block the cell cycle in G2 phase and induce apoptosis. HDAC-IN-46 can be used in triple negative breast cancer (TNBC) studies.
价 格:¥电议型 号:T62514产 地:中国大陆
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T62513MAX-40279;化合物 MAX-40279MAX-40279
MAX-40279 is a potent, dual FLT3 kinase and FGFR kinase inhibitor. MAX-40279 has potential for acute myeloid leukemia (AML) studies.
价 格:¥电议型 号:T62513产 地:中国大陆
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T62512IHMT-MST1-58;化合物IHMT-MST1-58IHMT-MST1-58
IHMT-MST1-58 is a STE20-like protein 1 kinase (MST1) inhibitor (IC50:23 nM) with high efficiency, selectivity and oral activity. IHMT-MST1-58 can be used to study type 1 or type 2 diabetes.
价 格:¥电议型 号:T62512产 地:中国大陆