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T62686MNK1/2-IN-6;化合物 MNK1/2-IN-6MNK1/2-IN-6
MNK1/2-IN-6 is a potent and selective inhibitor of MNK1 (IC50: 2.3 nM), MNK2 (IC50: 3.4 nM), and MNK1/2-IN-6 induces apoptosis in a concentration-dependent manner.
价 格:¥电议型 号:T62686产 地:中国大陆
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T62685IMP2-IN-2;化合物 IMP2-IN-2IMP2-IN-2
IMP2-IN-2 is a potent and selective inhibitor of IMP2 with IC50 values of 120.9 μM and 236.7 μM for the inhibition of IMP2 interaction with RNA_A and RNA_B, respectively. IMP2-IN-2 can be used in cancer research.
价 格:¥电议型 号:T62685产 地:中国大陆
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T62684Lartesertib;化合物 LartesertibATM Inhibitor-5|||M4076;ATM Inhibitor-5|||M4076
Lartesertib (ATM Inhibitor-5) is an inhibitor of serine/threonine protein kinase ATM with potential anticancer activity for the study of lung cancer.
价 格:¥电议型 号:T62684产 地:中国大陆
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T62683PRMT5-IN-3;化合物 PRMT5-IN-3PRMT5-IN-3
PRMT5-IN-3 is a PRMT5 inhibitor.PRMT5-IN-3 is a combined DNA damaging agent that is synthetically lethal to tumor cells.
价 格:¥电议型 号:T62683产 地:中国大陆
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T62682FGFR4-IN-10;化合物 FGFR4-IN-10FGFR4-IN-10
FGFR4-IN-10 (compound 5a) is a selective and potent inhibitor of FGFR4 (IC50: 70.7 nM).FGFR4-IN-10 does not inhibit other FGFR family members (i.e., FGFR1, FGFR2, and FGFR3).
价 格:¥电议型 号:T62682产 地:中国大陆
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T62681PDE5-IN-3;化合物 PDE5-IN-3PDE5-IN-3
PDE5-IN-3 (compound 11j) is a potent inhibitor of PDE5 (IC50: 1.57 nM). PDE5-IN-3 has a moderate inhibitory effect on EGFR (IC50: 5.827 μM). PDE5-IN-3 markedly inhibits the Wnt/β-catenin pathway with an IC50 value of 1286.96 ng/mL. PDE5-IN-3 induced the intrinsic apoptotic mitochondrial pathway in HepG2 cells, and PDE5-IN-3 exhibited significant antitumor effects.
价 格:¥电议型 号:T62681产 地:中国大陆
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T62680(R)-MLT-985;化合物 (R)-MLT-985(R)-MLT-985
(R)-MLT-985 (compound 11) is a potent inhibitor of MALT1 protease (IC50: 3 nM). (R)-MLT-985 has an IC50 value of 20 nM for MALT1-dependent IL-2 in Jurkat cells.(R)-MLT-985 inhibits growth and aberrant CARD11/BCL10/MALT1 complex signaling in ABC-DLBCL cells.
价 格:¥电议型 号:T62680产 地:中国大陆
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T6268Ceftiofur hydrochloride;头孢噻呋盐酸盐Ceftiofur HCl|||U-67279A|||Excenel hydrochloride;头孢噻呋盐酸盐|||Ceftiofur
Ceftiofur hydrochloride (U-67279A) is the hydrochloride salt form of ceftiofur, a semisynthetic, beta-lactamase-stable, broad-spectrum, third-generation cephalosporin with antibacterial activity.
价 格:¥电议型 号:T6268产 地:中国大陆
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T62679LSD1-IN-13 hydrochloride;化合物 LSD1-IN-13 hydrochlorideLSD1-IN-13 hydrochloride
LSD1-IN-13 hydrochloride (compound 7e) is an orally active inhibitor of LSD1 (IC50: 24.43 nM). hydrochloride induces differentiation of AML (acute myeloid leukemia) cell lines.
价 格:¥电议型 号:T62679产 地:中国大陆
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T62678YE6144;化合物 YE6144YE6144
YE6144 is a typical inhibitor of interferon regulatory factor 5 (IRF5), which inhibits IRF5 phosphorylation and thus selectively inhibits IRF5 activity.
价 格:¥电议型 号:T62678产 地:中国大陆
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T62677Ganaplacide hydrochloride;化合物 Ganaplacide hydrochlorideGanaplacide hydrochloride
Ganaplacide (KAF156) hydrochloride is a first-of-its-kind, orally active imidazolopiperazine antimalarial drug.Ganaplacide hydrochloride is active against a wide range of Plasmodium species, including drug-resistant parasites. hydrochloride is effective against both asexual and sexual blood stages as well as the liver stage.
价 格:¥电议型 号:T62677产 地:中国大陆
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T62676DS89002333;化合物 DS89002333DS89002333
DS89002333 is a potent, orally active PRKACA inhibitor (IC50: 0.3 nM).DS89002333 has shown good antitumor effects in a patient-derived xenograft model of FL-HCC expressing a DNAJB1-PRKACA fusion gene.DS89002333 can be used to study fibrotic hepatocellular carcinoma ( FL-HCC).
价 格:¥电议型 号:T62676产 地:中国大陆
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T62675FTI-277;化合物 FTI-277FTI-277
FTI-277 is a farnesyltransferase FTase inhibitor and a potent Ras CAAX peptide mimetic.FTI-277 inhibits H-Ras and K-Ras signaling and inhibits hepatitis delta virus (HDV) infection.
价 格:¥电议型 号:T62675产 地:中国大陆
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T62674LSD1-IN-21;化合物 LSD1-IN-21LSD1-IN-21
LSD1-IN-21 is a potent, blood-brain barrier permeable LSD1 (lysine specific demethylase-1) inhibitor (IC50: 0.956 μM).LSD1-IN-21 significantly reduces the pro-inflammatory cytokine TNF-α and exhibits good anti-cancer and anti-inflammatory effects.
价 格:¥电议型 号:T62674产 地:中国大陆
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T62673Mu opioid receptor antagonist 5;化合物 Mu opioid receptor antagonist 5Mu opioid receptor antagonist 5
Mu opioid receptor antagonist 5 (compound NAP) is a selective mu opioid receptor (MOR) antagonist that crosses the blood-brain barrier (EC50: 1.14 nM, Ki: 0.37 nM). Mu opioid receptor antagonist 5 can be used to study opioid use disorder (OUD).
价 格:¥电议型 号:T62673产 地:中国大陆
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T62672D5261;化合物 D5261D5261
D5261 is a potent, type III variant of tropomyosin-related kinase A (TrkA) inhibitor.
价 格:¥电议型 号:T62672产 地:中国大陆
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T62671FAAH/MAGL-IN-3;化合物 FAAH/MAGL-IN-3FAAH/MAGL-IN-3
FAAH/MAGL-IN-3 (Compound 10) is an irreversible dual inhibitor of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) that acts on FAAH (IC50: 179 nM) and MAGL (IC50: 759 nM). FAAH/MAGL-IN-3 showed little PAMPA (parallel artificial membrane permeability assay) permeability.
价 格:¥电议型 号:T62671产 地:中国大陆
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T62670Cemdomespib;化合物 CemdomespibCemdomespib
Cemdomespib (KU-596) is a potent second-generation Hsp90 modulator. cemdomespib induces a heat shock response, induces Hsp70 levels and has neuroprotective effects. cemdomespib has been shown to improve sensory deficits in models of diabetic peripheral neuropathy.
价 格:¥电议型 号:T62670产 地:中国大陆
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T6267Lomitapide;洛美他派AEGR-733|||BMS-201038;AEGR-733|||洛美他派|||BMS-201038
Lomitapide (AEGR-733) is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring triglycerides onto apolipoprotein B (apo-B) in the assembly of very-low-density lipoprotein.
价 格:¥电议型 号:T6267产 地:中国大陆
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T6266LPP2 Analog;化合物 T6266LPP2-Analog|||CHEMBL-306012|||CHEMBL306012|||CHEMBL 306012;PP2-Analog|||CHEMBL-3
PP2 Analog is an analog of PP2. It also acts as a protein trafficking modulator.
价 格:¥电议型 号:T6266L产 地:中国大陆