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T1167Cyproterone acetate醋酸环丙孕酮Androcur|||醋酸环丙氯地孕酮|||Cyproterone 17-O-acetate|||醋酸环丙孕酮
Cyproterone acetate (Cyproterone 17-O-acetate) binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues and inhibiting the growth of testosterone-sensitive tumor cells. Cyproterone acetate is the acetate salt of a synthetic steroidal antiandrogen with weak progestational and antineoplastic activities. This agent also exerts progestational agonist properties at the level of the pituitary that reduce luteinizing hormone (LH), resulting in reductio
价 格：￥电议型 号：T1167产 地：中国大陆
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T11669IR415；化合物IR415IR415
IR415 selectively interacts with Hepatitis B virus X protein (HBx, Kd = 2 nM) and blocks HBV-mediated RNAi suppression, reverses the inhibitory effect of HBx protein on the activity of the dicer endoribonuclease. IR415 is a potent anti-HBV agent and inhibits HBV replication by blocking the HBx activity.
价 格：￥电议型 号：T11669产 地：中国大陆
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T11668IQB-782；化合物 IQB-782IQB-782
IQB-782 is a mucolytic agent with mucolytic expectorant activity.IQB-782 inhibits thrombin-activating fibrinolytic inhibitor (TAFI), protects rats from tobacco smoke-induced respiratory obstruction, reduces the viscosity of gastric mucin suspensions in vitro, and may be useful in studies of obstructive lung disease.IQB-782 has been shown to reduce the viscosity of gastric mucin suspensions in vitro.
价 格：￥电议型 号：T11668产 地：中国大陆
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T11667Ipragliflozin (L-Proline)化合物 T11667Ipragliflozin L-Proline
Ipragliflozin is a highly potent and selective SGLT2 inhibitor with an IC50 of 2.8 nM; little and NO potency for SGLT1/3/4/5/6.
价 格：￥电议型 号：T11667产 地：中国大陆
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T11666IPR-803；化合物IPR-803IPR-803
IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity. IPR-803 binds directly to uPAR with a Ki of 0.2 μM.
价 格：￥电议型 号：T11666产 地：中国大陆
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T11665Ionomycin calcium；罗红霉素钙盐(链霉菌属载体)SQ23377 calcium；SQ23377 calcium|||罗红霉素钙盐(链霉菌属载体)
lonomycin calcium is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. also induces the activation of protein kinase C (PKC). Ionomycin calcium (SQ23377 calcium) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin promotes apoptosis.
价 格：￥电议型 号：T11665产 地：中国大陆
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T11664INY-03-041；化合物 T11664INY-03-041
INY-03-041, a potent and highly selective PROTAC-based pan-AKT degrader, inhibits AKT1, AKT2, and AKT3 with IC50s of 2.0 nM, 6.8 nM, and 3.5 nM, respectively. This compound consists of the ATP-competitive AKT inhibitor GDC-0068 conjugated to Lenalidomide.
价 格：￥电议型 号：T11664产 地：中国大陆
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T11663Integrin-IN-2；化合物 T11663Integrin-IN-2
Integrin-IN-2 is an orally bioavailable pan αv integrin inhibitor.Integrin-IN-2 can increases the αvβ6, αvβ3, αvβ5 and αvβ8 binding affinities with pIC50 values of 7.8, 8.4, 8.4 and 7.4, respectively.
价 格：￥电议型 号：T11663产 地：中国大陆
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T11662LINT-777；化合物INT-777S-EMCA；S-EMCA
INT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 μM. INT-777 (S-EMCA) inhibits NLRP5-ASC inflammasome-mediated neuroinflammation via the TGR3/cAMP/PKA signaling pathway after subarachnoid hemorrhage in rats.
价 格：￥电议型 号：T11662L产 地：中国大陆
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T11662INT-777 R-enantiomer；化合物 T11662S-EMCA R enantiomer；S-EMCA R enantiomer
INT-777 is the R-enantiomer of INT-777, less potent than INT-777,EC50 of 4.79 μM for TGR5.
价 格：￥电议型 号：T11662产 地：中国大陆
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T11661INT-767；化合物 INT-767INT-767
INT-767 is a potent farnesoid X receptor (FXR)/TGR5 dual agonist that prevents NASH and promotes visceral adipose brown lipogenesis and mitochondrial function for the study of non-alcoholic steatohepatitis.
价 格：￥电议型 号：T11661产 地：中国大陆
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T11660Insulin levels modulator；化合物 T11660Insulin levels modulator
Insulin level regulators can be used to treat diabetes.
价 格：￥电议型 号：T11660产 地：中国大陆
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T1166Ellipticine；玫瑰树碱NSC 71795|||Elliptisine；玫瑰树碱|||NSC 71795|||Elliptisine
Ellipticine (Elliptisine) is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.25±0.13, 0.67±0.06, 0.27±0.02, 0.49±0.04, 0.44±0.03, and 1.48±0.62 μM for Leukemia HL-60, Breast adenocarcinoma MCF-7, Breast adenocarcinoma MCF-7, Leukemia HL-60, Neuroblastoma IMR-32, Neuroblastoma UKF-NB-4, Neuroblastoma UKF-NB-3, and Glioblastoma U87 mg cell, respectively.
价 格：￥电议型 号：T1166产 地：中国大陆
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T11659Inogatran；伊诺加群H-314-27；伊诺加群|||H-314-27
Inogatran is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of venous and arterial thrombotic diseases.
价 格：￥电议型 号：T11659产 地：中国大陆
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T11657INH154；化合物INH154INH154
INH154 is a potent Nek2 and Hec1 binding (INH) inhibitor with IC50s of 120 nM in MB468 cells and 200 nM in Hela cells for INH.
价 格：￥电议型 号：T11657产 地：中国大陆
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T11655Indomethacin-D4；吲哚美辛-D4Indomethacin-D-4|||Indometacin-D4|||Indometacin-D4|||吲哚美辛-D4|||Indomethacin D
Indomethacin-D4 is a deuterium labeled Indomethacin. Indomethacin is a potent and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells.
价 格：￥电议型 号：T11655产 地：中国大陆
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T11654Indirubin Derivative E804；化合物 T11654Indirubin Derivative E804
Indirubin Derivative E804 is an effective inhibitor of IGF1R, which has an IC50 value of 0.65.
价 格：￥电议型 号：T11654产 地：中国大陆
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T11653Indirubin-5-sulfonate；化合物 T11653Indirubin-5-sulfonate
Indirubin-5-sulfonate shows inhibitory activity against GSK-3β. Indirubin-5-sulfonate is a cyclin-dependent kinase (CDK) inhibitor, with IC50 values of 55 nM, 35 nM, 150 nM, 300 nM and 65 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, and CDK5/p35, respectively.
价 格：￥电议型 号：T11653产 地：中国大陆
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T11651Indanidine；吲达尼定Indanidine
Indanidine is a highly selective and potent α-adrenergic agonist with antihypertensive activity.Indanidine is an α-adrenergic antagonist that can be used in the study of neurological disorders.
价 格：￥电议型 号：T11651产 地：中国大陆
