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T11611IDH1 Inhibitor 2;化合物 T11611IDH1 Inhibitor 2
IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).
价 格:¥电议型 号:T11611产 地:中国大陆
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T11610Idelalisib D5;化合物 T11610CAL-101 D5|||GS-1101 D5;CAL-101 D5|||GS-1101 D5
Idelalisib D5, a version of Idelalisib marked with deuterium, is an orally bioavailable and highly selective inhibitor of p110δ.
价 格:¥电议型 号:T11610产 地:中国大陆
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T1161Prothionamide;丙硫异烟胺1321-TH|||Protionamide;1321-TH|||Protionamide|||丙硫异烟胺
Prothionamide (1321-TH)is a thioamide derivative with antitubercular activity.
价 格:¥电议型 号:T1161产 地:中国大陆
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T11609ICI 153110;化合物 T11609ICI 153110
ICI 153110 is an orally active phosphodiesterase inhibitor with both inotropic and vasodilating properties. It is designed for the treatment of congestive cardiac failure.
价 格:¥电议型 号:T11609产 地:中国大陆
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T11608Epanolol;化合物 T11608Visacor|||ICI141292;Visacor|||ICI141292
Epanolol is a potent β-adrenoceptor partial agonist with a greater affinity for β1- than β2-adrenoceptors.
价 格:¥电议型 号:T11608产 地:中国大陆
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T11607ICI 118,551 hydrochloride;化合物ICI 118,551 hydrochlorideICI 118551 hydrochloride;ICI 118551 hydrochlor
ICI 118,551 hydrochloride (ICI 118551 hydrochloride) is a highly selective β2 adrenergic receptor antagonist (Kis: 0.7, 49.5, and 611 nM for β2, β1, and β3 receptors).
价 格:¥电议型 号:T11607产 地:中国大陆
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T11606ICA-105665;化合物 T11606PF-04895162;PF-04895162
ICA-105665 (PF-04895162) is a potent and orally active neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channels opener. ICA-105665 had low cytotoxic potential in human hepatocytes but inhibited liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 μM). ICA-105665 can penetrate the central nervous system (CNS) and has antiseizure effects[1][2][3][4].
价 格:¥电议型 号:T11606产 地:中国大陆
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T11605(-)-Ibuprofenamide;化合物 T11605(R)-Ibuprofenamide;(R)-Ibuprofenamide
(-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity.
价 格:¥电议型 号:T11605产 地:中国大陆
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T11604Ibuprofen-d3;化合物 T11604Ibuprofen D3|||(±)-Ibuprofen D3;Ibuprofen D3|||(±)-Ibuprofen D3
Ibuprofen D3 is a deuterium labeled Ibuprofen. Ibuprofen is a COX-1 and COX-2 inhibitor (IC50s: 13 μM and 370 μM).
价 格:¥电议型 号:T11604产 地:中国大陆
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T11603Ibrutinib-MPEA;化合物 T11603Ibrutinib-MPEA
Ibrutinib-MPEA is ibrutinib derivative. Ibrutinib is a covalent and irreversible BTK inhibitor that has been used to treat hematological malignancies.
价 格:¥电议型 号:T11603产 地:中国大陆
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T11602Ibrutinib dimer;依鲁替尼二聚体Ibrutinib dimer
Ibrutinib dimer is an impurity of Ibrutinib. IIbrutinib dimer is a Dimer of Ibrutinib. Ibrutinib is an irreversible Btk inhibitor (IC50: 0.5 nM).
价 格:¥电议型 号:T11602产 地:中国大陆
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T11601Ibrutinib-d5;化合物 T11601PCI-32765 D5|||Ibrutinib D5;PCI-32765 D5|||Ibrutinib D5
Ibrutinib D5 is a deuterium-labeled Ibrutinib. Ibrutinib is an irreversible Btk inhibitor.
价 格:¥电议型 号:T11601产 地:中国大陆
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T11600IBR2;化合物IBR2Isoquinoline;Isoquinoline
IBR2 (Isoquinoline) is a potent and specific RAD51 inhibitor known for its ability to suppress RAD51-mediated DNA double-strand break repair. By interfering with RAD51 multimerization, accelerating proteasome-mediated RAD51 protein degradation, inhibiting cancer cell growth, and inducing apoptosis, IBR2 has proved to be an effective compound in these aspects.
价 格:¥电议型 号:T11600产 地:中国大陆
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T1160Fusidic acid;夫西地酸Fusidine;Fusidine|||夫西地酸
Fusidic acid (Fusidine) is an antibiotic isolated from the fermentation broth of Fusidium coccineum.
价 格:¥电议型 号:T1160产 地:中国大陆
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T1158Phenoxybenzamine hydrochloride;盐酸酚苄明NCI-c01661|||NSC 37448|||Phenoxybenzamine HCl;苯氧苯札明|||NCI-c01661
Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non-selectively and irreversibly blocks the postsynaptic alpha-adrenergic receptor in smooth muscle, thereby preventing vasoconstriction, relieving vasospasms, and decreasing peripheral resistance. Reflex tachycardia may occur and may be enhanced by blockade of alpha-2 receptors whi
价 格:¥电议型 号:T1158产 地:中国大陆
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T11556HET0016;化合物 T11556HET0016
HET0016 is a potent and selective 20-HETE synthase inhibitor (IC50s: 17.7 nM, 12.1 nM, and 20.6 nM for recombinant CYP4A1-, CYP4A2- and CYP4A3-catalyzed 20-HETE synthesis). HET0016 also is a selective CYP450 inhibitor, which has been shown to inhibit angiogenesis and tumor growth.
价 格:¥电议型 号:T11556产 地:中国大陆
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T11525LGW311616 hydrochloride;化合物 T11525LGW311616A;GW311616A
GW-311616 hydrochloride is a long duration, orally bioavailable, and selective human neutrophil elastase (HNE) inhibitor (IC50: 22 nM; Ki: 0.31 nM).
价 格:¥电议型 号:T11525L产 地:中国大陆
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T11525GW311616;化合物 T11525GW311616
GW-311616 is a long duration, orally bioavailable, and selective human neutrophil elastase (HNE) inhibitor (IC50: 22 nM; Ki: 0.31 nM).
价 格:¥电议型 号:T11525产 地:中国大陆
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T11516GV-196771A;化合物GV-196771AGV-196771A
GV-196771A A novel NMDA receptor glycine site antagonist with potent antinociceptive activity.
价 格:¥电议型 号:T11516产 地:中国大陆
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T11488GSK2850163;化合物GSK2850163GSK2850163
GSK2850163 is a novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1α) which can inhibit RNase activity and IRE1α kinase activity (IC50s: 200 and 20 nM).
价 格:¥电议型 号:T11488产 地:中国大陆