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T11156LNazartinib mesylate;化合物 T11156LEGF816 (mesylate);EGF816 (mesylate)
Nazartinib mesylate is a novel, covalent mutant-selective inhibitor of EGFR (Ki and Kinact: 31 nM and 0.222/min on EGFR(L858R/790M) mutant).
价 格:¥电议型 号:T11156L产 地:中国大陆
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T11156Nazartinib S-enantiomer;化合物 T11156EGF816 (S-enantiomer);EGF816 (S-enantiomer)
Nazartinib is an EGFR inhibitor. Nazartinib S-enantiomer is the less active S-enantiomer of Nazartinib.
价 格:¥电议型 号:T11156产 地:中国大陆
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T11116Duocarmycin MA;倍癌霉素 MADuocarmycin MA
Duocarmycin MA can be used against multi-drug resistant cell lines.Duocarmycin MA is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove.
价 格:¥电议型 号:T11116产 地:中国大陆
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T11092DPBQ;化合物DPBQZINC1620467|||2,3-Diphenylbenzo[g]quinoxaline-5,10-dione;ZINC1620467|||2,3-Diphenylbenzo
DPBQ (ZINC1620467) is a p53 activator. DPBQ could activate p53 and trigger apoptosis in a polyploid-specific manner, without inhibition of topoisomerase or bind DNA.
价 格:¥电议型 号:T11092产 地:中国大陆
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T11090L1Aldoxorubicin hydrochloride;化合物Aldoxorubicin盐酸盐Aldoxorubicin hydrochloride (1361644-26-9 Free base);
Aldoxorubicin hydrochloride is an albumin-binding prodrug of Doxorubicin, a DNA topoisomerase II inhibitor. Aldoxorubicin hydrochloride is released from albumin under acidic conditions. Aldoxorubicin hydrochloride exhibits potent antitumor activities in various cancer cell lines and in murine tumor models.
价 格:¥电议型 号:T11090L1产 地:中国大陆
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T11087DOV-216,303 Free Base;化合物DOV-216,303 Free BaseDOV-216303;DOV-216303
DOV-216,303 Free Base (DOV-216303) is an inhibitor of serotonin, norepinephrine, and dopamine reuptake with with IC50s of 14, 20 and 78 nM. DOV-216,303 Free Base exhibits antidepressant effects.
价 格:¥电议型 号:T11087产 地:中国大陆
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T11073Dofetilide N-oxide;化合物 T11073UK-116856;UK-116856
Dofetilide N-oxide (UK-116856) is a metabolite of dofetilide. Dofetilide can block potassium channels and is a tertiary antiarrhythmic drug.
价 格:¥电议型 号:T11073产 地:中国大陆
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T1105Penfluridol;五氟利多R-16341|||TLP-607;五氟利多|||R-16341|||TLP-607
Penfluridol (TLP-607) is a highly potent antipsychotic.
价 格:¥电议型 号:T1105产 地:中国大陆
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T11016DGAT-1 inhibitor 2;化合物DGAT-1抑制剂2DGAT-1 inhibitor 2
DGAT-1 inhibitor 2 is an effective DGAT-1 inhibitor; anti-obesity drug. Objective: DGAT-1 acyl-CoA: diacylglycerol acyltransferase 1 (DGAT1) is one of two known DGAT enzymes that catalyze the final step of triglyceride synthesis. The discovery of transgenic mice and pharmacological studies indicate that inhibiting DGAT1 is a promising strategy for treating obesity and type 2 diabetes.
价 格:¥电议型 号:T11016产 地:中国大陆
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T10966DC-5163;化合物 T10966DC-5163
DC-5163 is a potent inhibitor of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with IC50 of 176.3 nM and Kd of 3.192 μM. DC-5163 selectively inhibits cancer cell proliferation and induces apoptosis, and partially inhibits the glycolysis pathway.
价 格:¥电议型 号:T10966产 地:中国大陆
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T10925LCysteine Protease inhibitor hydrochloride;化合物 T10925LCysteine Protease inhibitor hydrochloride (9216
Cysteine Protease inhibitor hydrochloride is a cysteine protease inhibitor.
价 格:¥电议型 号:T10925L产 地:中国大陆
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T10916Cycloguanil D6;化合物 T10916Chlorguanide triazine D6;Chlorguanide triazine D6
Cycloguanil D6 is a dihydrofolate reductase inhibitor, deuterium-labeled Cycloguanil.
价 格:¥电议型 号:T10916产 地:中国大陆
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T10852CNS-5161 hydrochloride;化合物CNS-5161盐酸盐CNS 5161A;CNS 5161A
CNS-5161 hydrochloride (CNS 5161A) is a new antagonist of NMDA ion-channel. It interacts with the NMDA receptor/ion channel site to produce a noncompetitive blockade of the actions of glutamate.
价 格:¥电议型 号:T10852产 地:中国大陆
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T10830CL 316243;化合物CL 316243CL 316243
CL316243 is a highly potent selective agonist of β3-adrenoceptor, with a EC50 of 3 nM. CL316243 is an effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate. CL316243 has the potential for the treatment obesity, diabetes and urge urinary incontinence.
价 格:¥电议型 号:T10830产 地:中国大陆
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T10816Cinnarizine D8;化合物 T10816Cinnarizine D8
Cinnarizine D8 is a deuterium-labeled Cinnarizine which is an antihistamine and a calcium channel blocker.
价 格:¥电议型 号:T10816产 地:中国大陆
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T10716CCR7 Ligand 1;化合物 T10716CCR7-Cmp2105;CCR7-Cmp2105
CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric Ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. CCR7 Ligand 1, thiadiazole-dioxide ligan, suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM.
价 格:¥电议型 号:T10716产 地:中国大陆
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T10616BRM/BRG1 ATP Inhibitor-1;化合物BRM/BRG1 ATP Inhibitor-1BRM/BRG1 ATP Inhibitor-1
BRM/BRG1 ATP Inhibitor-1 is an allosteric dual Brahma homolog (BRM)/SWI/SNF related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) and BRG1/SMARCA4 ATPase activity inhibitor (IC50s<0.005 μM).
价 格:¥电议型 号:T10616产 地:中国大陆
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T10588BPI-9016M;化合物 T10588BPI-9016M
BPI-9016M is an effective, orally active, and selective dual inhibitor of c-Met and AXL tyrosine kinases. It suppresses tumor cell growth, invasion, and migration of lung adenocarcinoma.
价 格:¥电议型 号:T10588产 地:中国大陆
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T10572LBMT-124110 Formate;BMT-124110甲酸盐BMT-124110 Formate(1679371-59-5 Free base);BMT-124110 Formate(167937
BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase BIKE with an IC50: 17 nM.BMT-124110 Formate inhibits the cell-cycle protein G-related BMT-124110 Formate inhibits the cell cycle protein G-associated kinase GAK with an IC50:99 nM.
价 格:¥电议型 号:T10572L产 地:中国大陆
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T10552Bitopertin (R enantiomer);化合物 T10552RO4917838 (R enantiomer)|||RG1678 (R enantiomer)|||Bitopertin R
Bitopertin R enantiomer (RG1678 R enantiomer) is the R-enantiomer of Bitopertin. Bitopertin is a noncompetitive glycine reuptake inhibitor and inhibits glycine uptake at human GlyT1 (IC50: 25 nM).
价 格:¥电议型 号:T10552产 地:中国大陆