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T11439GNE-616;化合物 T11439GNE-616
GNE-616 is a highly potent, metabolically stable, orally bioavailable, and subtype-selective Nav1.7 inhibitor (Ki: 0.79 nM, Kd: 0.38 nM for hNav1.7) for the treatment of chronic pain.
价 格:¥电议型 号:T11439产 地:中国大陆
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T11416Glucagon receptor antagonists-5;化合物 T11416Glucagon receptor antagonists-5
Glucagon receptor antagonists-5 is an orally bioavailable indazole-based glucagon receptor antagonist (Ki: 32 nM). It has potential for the treatment of type 2 diabetes mellitus (T2DM).
价 格:¥电议型 号:T11416产 地:中国大陆
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T11342G-5555 hydrochloride (1648863-90-4 free base);化合物 T11342G-5555 hydrochloride;G-5555 hydrochloride
G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM.
价 格:¥电议型 号:T11342产 地:中国大陆
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T11327LFR 167653 free base;化合物 T11327LFR 167653 free base
FR 167653 free base is an orally active p38 MAPK inhibitor and is effective in treating inflammation, relieving trauma, and ischemia-reperfusion injury in vivo. It also is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MAPK activity.
价 格:¥电议型 号:T11327L产 地:中国大陆
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T11316FOY 251 free base;化合物 T11316FOY 251 free base
FOY 251 free base acts as a proteinase inhibitor. FOY 251 free base is an anti-proteolytic active metabolite camostate.
价 格:¥电议型 号:T11316产 地:中国大陆
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T11276Fexofenadine-d6;非索非那定 d6MDL-16455-d6|||Terfenadine carboxylate-d6;MDL-16455-d6|||Terfenadine carboxy
Fexofenadine-d6 (MDL-16455-d6) is the deuterium substituent of Fexofenadine and can be used as an internal standard for the determination of non-sofenadine concentrations in human plasma.
价 格:¥电议型 号:T11276产 地:中国大陆
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T11247Etravirine D4;依曲韦林 D4R-165335 D4|||TMC-125 D4;R-165335 D4|||TMC-125 D4|||依曲韦林 D4
Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. Etravirine D4 is the deuterium labeled Etravirine.
价 格:¥电议型 号:T11247产 地:中国大陆
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T11216Eplivanserin (mixture)化合物 T11216Eplivanserin mixture|||SR-46349 (mixture)
Eplivanserin mixture is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist,
价 格:¥电议型 号:T11216产 地:中国大陆
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T11204ENS-163 phosphate;化合物 T11204Sandoz ENS 163 phosphate|||ENS 213-163|||Thiopilocarpine phosphate;Sando
Ens-163 phosphate is a muscarinic M1 receptor agonist. It is selective.
价 格:¥电议型 号:T11204产 地:中国大陆
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T11169Eicosatetraynoic acid;化合物 T11169ETYA;ETYA
Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 μM. Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively).
价 格:¥电议型 号:T11169产 地:中国大陆
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T11168EHNA hydrochloride;外消旋-9-(2-羟基-3-壬基)腺嘌呤盐酸盐EHNA hydrochloride
EHNA hydrochloride is a chemical compound recognized for its antiviral, antitumor, and antiarrhythmic properties. It functions as a potent and selective inhibitor of both cyclic nucleotide phosphodiesterase 2 (PDE2) with an IC50 of 4 μM and adenosine deaminase (ADA). Additionally, it effectively inhibits the activity of cGMP-stimulated PDE II (cGs-PDE) with IC50 values of 0.8 μM in humans and 2 μM in porcine myocardium, although its inhibitory effects on unstimulated PDE2 activity are less prono
价 格:¥电议型 号:T11168产 地:中国大陆
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T11167EHMT2-IN-2;化合物 T11167EHMT2-IN-2
EHMT2-IN-2 Used in the research of blood disease or cancer. EHMT2-IN-2 is a potent EHMT inhibitor, with IC50s of all <100 nM for EHMT1 peptide, EHMT2 peptide and cellular EHMT2.
价 格:¥电议型 号:T11167产 地:中国大陆
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T11166EHMT2-IN-1;化合物 T11166EHMT2-IN-1
EHMT2-IN-1 is a potent EHMT inhibitor, . Used in the research of blood disorder or cancer.with IC50s of all <100 nM for EHMT1 peptide, EHMT2 peptide and cellular EHMT2.
价 格:¥电议型 号:T11166产 地:中国大陆
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T11165EGLU;化合物 T11165(2S)-α-EGLU|||(2S)-α-Ethylglutamic acid;(2S)-α-EGLU|||(2S)-α-Ethylglutamic acid
EGLU, also known as (2S)-α-Ethylglutamic acid or (2S)-α-EGLU, is a potent and competitive antagonist of the mGluR-2 receptor, demonstrating a Kd value of 66 μM when interacting with the (lS,3S)-ACPD-sensitive site. This chemical compound functions as an antidepressant agent.
价 格:¥电议型 号:T11165产 地:中国大陆
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T11164EGFR mutant-IN-1;化合物 T11164EGFR mutant-IN-1
EGFR mutant- in-1, A 5-methylpyrimidopyridone derivative are effective selective EGFRL858R/T790M/C797S mutant inhibitors with IC50 of 27.5 nM, which significantly weakened EGFRWT effect.
价 格:¥电议型 号:T11164产 地:中国大陆
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T11163EGFR-IN-9;化合物EGFR-IN-9EGFR-IN-9
EGFR-IN-9 is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity.
价 格:¥电议型 号:T11163产 地:中国大陆
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T11162EGFR-IN-8;化合物EGFR-IN-8EGFR-IN-8
EGFR-IN-8, a dual inhibitor targeting both EGFR and c-Met, shows potential as a promising candidate for further development in treating EGFR TKI-resistant NSCLC.
价 格:¥电议型 号:T11162产 地:中国大陆
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T11161EGFR-IN-7;化合物EGFR-IN-7TQB3804;TQB3804
EGFR-IN-7 (TQB3804) is a selective and potent EGFR kinase inhibitor.
价 格:¥电议型 号:T11161产 地:中国大陆
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T11160EGFR-IN-5;化合物EGFR-IN-5EGFR-IN-5|||inhibit|||Epidermal growth factor receptor|||HER1|||ErbB-1|||Inhib
EGFR-IN-5 is a selective inhibitor of EGFR. The IC50s for EGFR, EGFR(L858R), EGFR(L858R/T790M), and EGFR(L858R/T790M/C797S) are 10.4, 1.1, 34, 7.2 nM, respectively.
价 格:¥电议型 号:T11160产 地:中国大陆
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T1116Biotin;生物素Vitamin B7|||D-Biotin|||Vitamin H;Vitamin B7|||生物素|||D-Biotin|||Vitamin H|||D-生物素(维生素H)
Biotin (Vitamin H) is a naturally occurring, water-soluble B vitamin involved in fatty acid production, fat and amino acid metabolism, and cell growth. Biotin is often used for biotin labeling.
价 格:¥电议型 号:T1116产 地:中国大陆