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  • T71625ZK-304709 HCl；化合物 ZK-304709 HClZK-304709 HCl

    ZK-304709 is an oral multitarget tumor growth inhibitor with activity against cell-cycle progression and angiogenesis.

    价 格：￥电议型 号：T71625产 地：中国大陆

  • T71588Batanopride HCl；化合物 Batanopride HClBatanopride HCl

    Batanopride is a antiemetic 5-HT3 receptor antagonist.

    价 格：￥电议型 号：T71588产 地：中国大陆

  • T71564GSK2018682 HCl；化合物 GSK2018682 HClGSK2018682 HCl

    GSK2018682 is a novel sphingosine-1-phosphate receptor 1 (s1p1) and 5 (s1p5) agonist.

    价 格：￥电议型 号：T71564产 地：中国大陆

  • T71534CIA-1 hcl(452087-38-6 Free base)；化合物CIA-1 hcl(452087-38-6 Free base)CIA-1 hcl(452087-38-6 Free base)

    CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines.CIA-1 inhibits the growth of a variety of prostate cancer cell lines in vitro and inhibits COUP-TFII activity to regulate its target genes.CIA-1 in vivo exhibits tumor growth inhibitory effects in a mouse model of prostate cancer xenografts. inhibitory effect on tumor growth in a xenograft mouse model of prostate cancer in vivo.

    价 格：￥电议型 号：T71534产 地：中国大陆

  • T7148L1Josamycin HCl；化合物 T7148L1Josamycin hydrochloride|||Leucomycin A3 hydrochloride；Josamycin hydrochlori

    Josamycin HCl is a macrolide antibiotic.

    价 格：￥电议型 号：T7148L1产 地：中国大陆

  • T71467Nemorubicin HCL；化合物 Nemorubicin HCLNemorubicin HCL

    Nemorubicin HCL is the salt form of Nemorubicin, also known as PNU152243A, a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile. The drug is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives. It works primarily through topoisomerase I inhibition. Of note, Nemorubicin is active in cells with upregulation of the nucleotide excision repair (NER) pathway

    价 格：￥电议型 号：T71467产 地：中国大陆

  • T71444GYKI-12743 HCl；化合物 GYKI-12743 HClGYKI-12743 HCl

    GYKI-12743 HCl is a postsynaptic vascular alpha-adrenoceptor antagonist.

    价 格：￥电议型 号：T71444产 地：中国大陆

  • T71400Quizartinib HCl；化合物 Quizartinib HClQuizartinib HCl

    Quizartinib, also know as AC220 and AC010220, is an orally available FLT3 / STK1 inhibitor with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III receptor tyrosine kinases, including FMS-related tyrosine kinase 3 (FLT3/STK1), colony-stimulating factor 1 receptor (CSF1R/FMS), stem cell factor receptor (SCFR/KIT), and platelet derived growth factor receptors (PDGFRs), resulting in inhibition of ligand-independent leukemic cell pro

    价 格：￥电议型 号：T71400产 地：中国大陆

  • T71371HOE-166 HCl；化合物 HOE-166 HClHOE-166 HCl

    HOE-166 HCl is a novel calcium receptor antagonist.

    价 格：￥电议型 号：T71371产 地：中国大陆

  • T71370ICI-204879 HCl；化合物 ICI-204879 HClICI-204879 HCl

    ICI-204879 HCl is a potent and selective agonists at the opioid kappa-receptor.

    价 格：￥电议型 号：T71370产 地：中国大陆

  • T71356Lanperisone HCl；化合物 Lanperisone HClLanperisone HCl

    Lanperisone, also known as NK433, is a muscle relaxant. NK433 inhibited the facilitation of the flexor reflex mediated by group II afferent fibers that was induced by intrathecal administration of noradrenaline-HCl. NK433 had effects more than three times stronger and tending to be longer-lasting than those of eperisone-HCl. These results suggest that NK433 exerts a non-selective inhibition on spinal reflexes and that inhibition of the descending noradrenergic tonic facilitation within the spina

    价 格：￥电议型 号：T71356产 地：中国大陆

  • T71339XL413 HCl；XL413 盐酸盐XL413 hydrochloride|||BMS-863233 HCl；XL413 hydrochloride|||BMS-863233 HCl

    XL413 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.XL413 HCl inhibited CK2 and PIM1 with IC50 values of 215 and 42 nM, respectively.XL413 HCl showed an EC50 value of 118 against pMCM.

    价 格：￥电议型 号：T71339产 地：中国大陆

  • T71338Patidegib HCl；化合物 Patidegib HClPatidegib HCl

    Patidegip, laos known as Saridegib and IPI-926, is an orally bioavailable, cyclopamine-derived (for structure comparison see Fig 1) inhibitor of the Hedgehog (Hh) pathway with potential antineoplastic activity. Specifically, Hedgehog pathway inhibitor IPI-926 binds to and inhibits the cell membrane-spanning G-protein coupled receptor SMO, which may result in the suppression of Hh pathway signaling and a decrease in tumor cell proliferation and survival. SMO is activated upon binding of Hh ligan

    价 格：￥电议型 号：T71338产 地：中国大陆

  • T71333Iganidipine HCl；化合物 Iganidipine HClIganidipine HCl

    NKY-722 (HCl), also known as Iganidipine, is a calcium channel blocker potentially for thetreatment of glaucoma.

    价 格：￥电议型 号：T71333产 地：中国大陆

  • T71302Norfluoxetine-d5 HCl；化合物 Norfluoxetine-d5 HClNorfluoxetine-d5 HCl

    Norfluoxetine-d5 is intended for use as an internal standard for the quantification of norfluoxetine by GC- or LC-MS. Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15 nM). It has been found in the tissues of fish exposed to wastewa

    价 格：￥电议型 号：T71302产 地：中国大陆

  • T71301Opaganib HCl；化合物 Opaganib HClOpaganib HCl

    ABC294640, also known as Opaganib, is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase-2 (SK2) with potential antineoplastic activity. Upon administration, ABC294640 competitively binds to and inhibits SK2, thereby preventing the phosphorylation of the pro-apoptotic amino alcohol sphingosine to sphingosine 1-phosphate (S1P), the lipid mediator that is pro-survival and critical for immunomodulation. This may eventually lead to the induction of apoptosis a

    价 格：￥电议型 号：T71301产 地：中国大陆

  • T71298Ipenoxazone HCl；化合物 Ipenoxazone HClIpenoxazone HCl

    Ipenoxazone HCl is a glutamate receptor antagonist potentially for the treatment of Alzheimer´s disease.

    价 格：￥电议型 号：T71298产 地：中国大陆

  • T71290EVT-101 HCl；化合物 EVT-101 HClEVT-101 HCl

    EVT-101 is a GluN2B antagonist, binding at the same GluN1/GluN2B dimer interface as ifenprodil but adopting a remarkably different binding mode involving a distinct subcavity and receptor interactions.

    价 格：￥电议型 号：T71290产 地：中国大陆

  • T71266Omadacycline HCl；化合物 Omadacycline HClOmadacycline HCl

    Omadacycline, also known as PTK 0796 and Amadacyclin, is a novel first-in-class aminomethylcycline with potent activity against important skin and pneumonia pathogens, including community-acquired methicillin-resistant Staphylococcus aureus (MRSA), β-hemolytic streptococci, penicillin-resistant Streptococcus pneumoniae, Haemophilus influenzae, and Legionella. Omadacycline is active against strains expressing the two main forms of tetracycline resistance (efflux and ribosomal protection). The pri

    价 格：￥电议型 号：T71266产 地：中国大陆

  • T71254Clopidogrel HCl；化合物 Clopidogrel HClClopidogrel HCl

    Clopidogrel HCl is the salt form of Clopidogrel (free base), an inhibitor of ADP-induced platelet aggregation acting by direct inhibition of adenosine diphosphate (ADP) binding to its receptor and of the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex.

    价 格：￥电议型 号：T71254产 地：中国大陆

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