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T23139PF 514273;化合物 T23139PF 514273
PF 514273 is a CB1 receptor antagonist.
价 格:¥电议型 号:T23139产 地:中国大陆
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T23138PF 4800567 hydrochloride化合物 T23138PF 4800567 hydrochloride
casein kinase 1ε inhibitor
价 格:¥电议型 号:T23138产 地:中国大陆
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T22557UPF-523;化合物 T22557AIDA;AIDA
group I metabotropic glutamate receptors (mGlu1a) antagonist
价 格:¥电议型 号:T22557产 地:中国大陆
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T22397PF-4618433化合物PF-4618433PF4618433|||PF 4618433
PF-4618433 is a dual inhibitor of focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2).
价 格:¥电议型 号:T22397产 地:中国大陆
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T22396PF-6274484;化合物PF 6274484PF 6274484;PF 6274484
PF-6274484, a high affinity, irreversible covalent inhibitor of EGFR kinase with Ki of 0.14 nM, inhibits the autophosphorylation of wild-type EGFR in A549 cells and EGFRL858R/T790M in H1975 cells with IC50 of 5.8 nM and 6.6 nM, respectively.
价 格:¥电议型 号:T22396产 地:中国大陆
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T2177Kaempferol;山奈酚Kempferol|||Robigenin;Kempferol|||山柰酚|||山奈酚|||Robigenin
Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ. Kaempferol has a wide range of antitumor, anti-inflammatory, antioxidant, antibacterial and antiviral activities.
价 格:¥电议型 号:T2177产 地:中国大陆
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T21768PF-562271 hydrochloride化合物PF-562271 HClPF-562271 HCl
PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
价 格:¥电议型 号:T21768产 地:中国大陆
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T21738PF-9184;化合物PF-9184PF-9184
PF-9184 is a potent and selective inhibitor of human microsomal prostaglandin E synthase-1 (mPGES-1), IC50 =16.5 nM. PF-9184 inhibits IL-1β-induced PGE2 synthesis in vitro.
价 格:¥电议型 号:T21738产 地:中国大陆
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T21602PF-04880594;化合物 T21602PF-04880594
PF-04880594 is a potent and selective RAF inhibitor which inhibits both wild-type and mutant BRAF and CRAF. PF-04880594 exhibits antitumor activity [1].
价 格:¥电议型 号:T21602产 地:中国大陆
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T21548PF-4981517;化合物PF-4981517CYP3cide;CYP3cide
PF-4981517 (CYP3cide) is a efficient, specific and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4). The IC 50 values for CYP3A activity are 0.03 μM,17 μM, and 71 μM for CYP3A4, CYP3A5, and CYP3A7, respectively. PF-4981517 is able to be used to distinguish the contributions of CYP3A4 versus CYP3A5 on drug Metabolism.
价 格:¥电议型 号:T21548产 地:中国大陆
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T21322Mavelertinib;化合物MavelertinibPF 06747775|||PFE-X775|||PF-06747775|||PF-7775|||PF 6747775|||PF6747775;
Mavelertinib (PF-06747775) is an orally available, selective and potent EGFR tyrosine kinase (EGFR TKI) inhibitor with inhibitory effects on T790M/L858R and T790M/Del, and can be used in the study of oncology and respiratory diseases.
价 格:¥电议型 号:T21322产 地:中国大陆
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T21129Axitinib sulfoxide;化合物 T21129Axitinib metabolite M12|||PF-03482595|||AG-028458;Axitinib metabolite M
Axitinib sulfoxide is a major metabolite of Axitinib, which is a VEGFR tyrosine kinase inhibitor and may be useful in cancer therapy.
价 格:¥电议型 号:T21129产 地:中国大陆
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T2093L(S)-PF-03716556;化合物(S)-PF-03716556(S)-PF-03716556
(S)-PF-03716556 can be used as an acid pump inhibitor for the treatment of disease conditions mediated by acid pump inhibitory activity.
价 格:¥电议型 号:T2093L产 地:中国大陆
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T2093PF 03716556化合物PF 03716556PF-3716556
PF 03716556 (PF-3716556) , an effective and specific P-CAB (potassium-competitive acid blocker), is utilized for the treatment of gastroesophageal reflux disease.
价 格:¥电议型 号:T2093产 地:中国大陆
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T2050PF-06447475;化合物PF-06447475PF-06447475
PF-06447475 is a highly effective, specific, brain penetrant LRRK2 inhibitor with IC0 of 3/11 nM for wild type LRRK2 and G2019S LRRK2 respectively.
价 格:¥电议型 号:T2050产 地:中国大陆
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T2012Oclacitinib;化合物OclacitinibPF-03394197;PF-03394197
Oclacitinib (PF-03394197)(PF03394197) is a potent and selective JAKs inhibitor with IC50 of 10-99 nM; not inhibit a panel of 38 non-JAK kinases (IC50 ´s > 1000 nM).
价 格:¥电议型 号:T2012产 地:中国大陆
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T2002PF-4708671;化合物PF-4708671PF4708671;PF4708671
PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) .In cell-free assays, PF-4708671(PF4708671) is potent for S6K1(Ki50=20 nM, IC50=160 nM).
价 格:¥电议型 号:T2002产 地:中国大陆
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T2001PF-573228;化合物PF 573228PF 573228;PF 573228
PF-573228 is an ATP-competitive FAK inhibitor. In a cell-free assay, the IC50 of FAK is 4 nM.
价 格:¥电议型 号:T2001产 地:中国大陆