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  • T37691Phosphatidic Acids (egg) (ammonium salt)；Phosphatidic Acids (egg) (ammonium salt)Phosphatidic Acids

    Phosphatidic acid is a phospholipid and an intermediate in glycerolipid biosynthesis. It is a transient intermediate in the synthesis of various phospholipid species that is synthesized de novo in cells via multiple routes, including the glycerol-3 phosphate and dihydroxyacetone phosphate pathways, enzymatic conversion of phosphatidylcholine by phospholipase D, and acetylation of lysophosphatidic acid by lysoPA-acyltransferase, among others. It has roles in shaping cellular membranes, cellular

    价 格：￥电议型 号：T37691产 地：中国大陆

  • T37687Cyclic ADP-ribose ammonium；Cyclic ADP-ribose ammoniumCyclic ADP-ribose ammonium

    Cyclic ADP-ribose ammonium (cADPR ammonium) is a powerful calcium mobilization second messenger synthesized from NAD+ by an ADP-ribosyl cyclase. It primarily raises cytosolic calcium levels through Ryanodine receptor-mediated release from the endoplasmic reticulum, while also facilitating extracellular influx through the opening of TRPM2 channels [1][2][3].

    价 格：￥电议型 号：T37687产 地：中国大陆

  • T37582Ganglioside GM1 Mixture (ovine) (ammonium salt)；Ganglioside GM1 Mixture (ovine) (ammonium salt)Gangl

    Ganglioside GM1is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue.1,2It is found in a large variety of cells, including immune cells and neurons, and is enriched in lipid rafts in the cell membrane.3It associates with growth factor receptors, including TrkA, TrkB, and the GDNF receptor complex containing Ret and GFRα, and is required for TrkA expression on the cell surface. Ganglioside GM1interacts with other proteins to increase calcium i

    价 格：￥电议型 号：T37582产 地：中国大陆

  • T37517D-NMMA (acetate)；D-NMMA (acetate)D-NMMA (acetate)

    D-NMMA (acetate) can be used in related research in the field of life sciences. Its product number is T37517 and CAS number is 137694-75-8.

    价 格：￥电议型 号：T37517产 地：中国大陆

  • T37475Cyclic ADP-Ribose (ammonium salt)；Cyclic ADP-Ribose (ammonium salt)cADP-Ribose|||cADPR|||Cyclic ADP-

    Cyclic ADP-ribose (cADP-ribose) is an endogenous metabolite of NAD+ that mobilizes the release of stored Ca2+ in the endoplasmic reticulum via ryanodine receptors in various cell types.[1],[2],[3],[4],[5] This second messenger is generated via the cADP-ribose synthases CD38 and CD157.[6],[5],[7] cADP-Ribose may also trigger the cell surface Ca2+ influx channel TRPM2 in a temperature-dependent manner.[8]

    价 格：￥电议型 号：T37475产 地：中国大陆

  • T373465-Hydroxytoluene-2,4-disulphonic acid diammonium；5-Hydroxytoluene-2,4-disulphonic acid diammonium5-H

    5-Hydroxytoluene-2,4-disulphonic acid diammonium, an impurity of Policresulen, is a significant NS2B/NS3 protease inhibitor, exhibiting an IC50 value of 0.48 μg/mL. It inhibits DENV2 virus replication in BHK-21 cells effectively, with an IC50 of 4.99 μg/mL. Policresulen functions as a competitive inhibitor, marginally impacting the protease´s stability[1].

    价 格：￥电议型 号：T37346产 地：中国大陆

  • T37315Fluo-3 (ammonium salt)；Fluo-3 (ammonium salt)Fluo-3 (ammonium salt)

    Fluo-3 (ammonium salt) is a fluorescent calcium indicator commonly used in flow cytometry and cell-based experiments to detect changes in intracellular calcium levels. [1] Its absorption maximum at 506 nm makes it compatible with excitation at 488 nm by argon-ion laser sources. Fluo-3 provides intense fluorescence upon binding calcium, detected at a maximum emission at 526 nm which can be monitored by FL1 (green, 525 nm band pass) sensors in flow cytometry.

    价 格：￥电议型 号：T37315产 地：中国大陆

  • T37309Diadenosine pentaphosphate pentaammonium；Diadenosine pentaphosphate pentaammoniumDiadenosine pentaph

    Diadenosine pentaphosphate pentaammonium, an endogenous vasoactive purine dinucleotide isolated from thrombocytes, is one component of the diadenosine polyphosphates (ApnA, n=2-7) family. These compounds are found in secretory vesicles, including those in platelets, chromaffin cells, Torpedo synaptic terminals, and brain synaptosomes[1][2].

    价 格：￥电议型 号：T37309产 地：中国大陆

  • T37172MMP-9/MMP-13 Inhibitor I；MMP-9/MMP-13 Inhibitor IMMP-9/MMP-13 Inhibitor I

    MMP-9/MMP-13 Inhibitor I is a dual inhibitor of MMP-9 and MMP-13 with IC50 of both 0.9 nM. MMP-9/MMP-13 Inhibitor I is over 20 times more selective for MMP-9/MMP-13 than other MMPs.

    价 格：￥电议型 号：T37172产 地：中国大陆

  • T37059D-myo-Inositol-1,3,4,6-tetraphosphate (ammonium salt)；D-myo-Inositol-1,3,4,6-tetraphosphate (ammoniu

    The inositol phosphates (IPs) are a family of molecules produced by altering the phosphorylation status of each of the six carbons on the cyclic inositol structure. They act as second messengers, regulating a wide array of cellular functions. D-myo-inositol-1,3,4,6-tetraphosphate(Ins(1,3,4,6)-P4) largely acts an intermediate, serving as substrate for inositol-1,3,4,6-tetraphosphate 5-kinase to produce inositol-1,3,4,5,6-pentaphosphate, or inositol-1,3,4,6-tetraphosphate 2-kinase to give inositol

    价 格：￥电议型 号：T37059产 地：中国大陆

  • T37048LMMP-3 Inhibitor acetate；化合物MMP-3 Inhibitor acetateMMP-3 Inhibitor acetate(158841-76-0 Free base)；MMP

    MMP-3 Inhibitor acetate is a cell-permeable and potent inhibitor of human MMP-3.

    价 格：￥电议型 号：T37048L产 地：中国大陆

  • T37048MMP-3 Inhibitor；MMP-3抑制剂MMP-3 Inhibitor

    MMP-3 Inhibitor is a peptide matrix metalloproteinase-3 (MMP-3) inhibitor with a Ki value of 95 nM.MMP-3 inhibitor has anticancer and antitumor activity.

    价 格：￥电议型 号：T37048产 地：中国大陆

  • T37030PtdIns-(4)-P1 (1,2-dioctanoyl) (ammonium salt)；PtdIns-(4)-P1 (1,2-dioctanoyl) (ammonium salt)PtdIns-

    The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4)-P1 (1,2-dioctanoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) featuring C8:0 fatty acids at the sn-1 and sn-2 positions. The compound contains the same inositol and diacylglycerol (DAG) stereochemistry as the natural compound. PtdIns-(4)-P1 can be phosphorylated to di-

    价 格：￥电议型 号：T37030产 地：中国大陆

  • T370027-Fluoro-2,1,3-benzoxadiazole-4-sulfonate (ammonium salt)；7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate

    7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate (SBD-F) is a thiol-reactive fluorogenic probe.1It has been used to quantify the levels of homocysteine, cysteine, and cysteamine in human plasma.2SBD-F displays excitation/emission maxima of 380/515 nm, respectively.1

    价 格：￥电议型 号：T37002产 地：中国大陆

  • T36962MMP Inhibitor I (trifluoroacetate salt)；MMP Inhibitor I (trifluoroacetate salt)MMP Inhibitor I (trif

    MMP inhibitor I is a peptide inhibitor of matrix metalloproteinase-1 (MMP-1), MMP-2, and MMP-3 (IC50s = 1.3, 30, and 150 μM, respectively). It is selective for MMP-1, MMP-2, and MMP-3 over the proteases thermolysin, urease, trypsin, α-chymotrypsin, plasmin, and elastase at concentrations up to 4 mM.

    价 格：￥电议型 号：T36962产 地：中国大陆

  • T36939PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt)；PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt

    The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3, also known as PIP3, is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. PIP3 can serve as an anchor for the binding of signal transd

    价 格：￥电议型 号：T36939产 地：中国大陆

  • T36881NHC-diphosphate triammonium；NHC-diphosphate triammoniumNHC-diphosphate triammonium

    NHC-triphosphate triammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a triphosphate form[1]. NHC-triphosphate triammonium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA[1][2].

    价 格：￥电议型 号：T36881产 地：中国大陆

  • T36863Geranylgeranyl Pyrophosphate (ammonium salt)；Geranylgeranyl Pyrophosphate (ammonium salt)Geranylgera

    Geranylgeranyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway derived directly from farnesyl pyrophosphate and used in the biosynthesis of terpenes and terpenoids.[1] It is also serves as a substrate in the prenylation of a variety of critical intracellular proteins including small GTPases.[2] This post-translational modification is necessary for correct localization of proteins to intracellular membranes for proper functionality and has become a focus of anticancer drug disco

    价 格：￥电议型 号：T36863产 地：中国大陆

  • T36712BPHA；MMP-2/MMP-9抑制剂IIMMP-2/MMP-9 Inhibitor II；MMP-2/MMP-9 Inhibitor II

    BPHA (MMP-2/MMP-9 Inhibitor II) is a potent, selective and orally active inhibitor of MMP-2, MMP-9 and MMP-14 with IC50s of 12 nM, 16 nM and 17 nM, respectively.BPHA does not inhibit MMP-1, -3 and -7 (IC50s of 974, >1000 and 795 nM, respectively).BPHA has anti-angiogenic and BPHA has anti-angiogenic and anti-tumor activities.

    价 格：￥电议型 号：T36712产 地：中国大陆

  • T364521-Arachidonoyl Lysophosphatidic Acid (ammonium salt)；1-Arachidonoyl Lysophosphatidic Acid (ammonium

    1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position. It has been found in rat brain as 37% of the arachidonic acid-containing lysophosphatidic acid (LPA) species and is a precursor to 1-arachidonoyl glycerol . 1-Arachidonoyl lysophosphatidic acid binds to the LPA2/EDG4 receptor with an EC50 value of approximately 10 nM. It prevents TNF-α and IL-6 secretion in wild-type but not Lpa2-/- dendritic cells stimulated by LPS. It also decreases differe

    价 格：￥电议型 号：T36452产 地：中国大陆

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