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T36421Immuno-Oncology Screening Library；Immuno-Oncology Screening LibraryImmuno-Oncology Screening Library
The Immuno-Oncology Screening Library consists of 2 plates and contains more than 90 cancer and immunology-associated compounds in a 96-well Matrix tube rack format as 10 mM stock solutions in DMSO. This library includes a variety of immuno-oncology target modulators, including but not limited to, adenosine, CCR, CXCR, and TLR agonists and antagonists, BTK, PI3K, VEGFR, and BRAF inhibitors, PD-1/PDL-1 interaction inhibitors, and HDAC inhibitors. Please review the product insert for a full list
价 格：￥电议型 号：T36421产 地：中国大陆
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T36413N-glycolyl-Ganglioside GM3 Mixture (ammonium salt)；N-glycolyl-Ganglioside GM3 Mixture (ammonium salt
N-glycolyl-Ganglioside GM3(NeuGc-GM3) is a form of ganglioside GM3 that contains an N-glycolylated sialic acid (NeuGc).
价 格：￥电议型 号：T36413产 地：中国大陆
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T36357Dimethyldioctadecylammonium (bromide)；Dimethyldioctadecylammonium (bromide)Dimethyldioctadecylammoni
Dimethyldioctadecylammonium (DDA) is a cationic amphipathic lipid. DDA liposomes containing an Ag85B-ESAT-6 antigen induce antigen deposition at an intramuscular or subcutaneous injection site in mice, increasing immune cell exposure to the antigen. In a guinea pig model of M. tuberculosis infection, spleen bacterial load is reduced and lung and spleen lesion numbers are decreased when the mycobacterial lipid antigens Ac2SGL and PIM2 are administered in liposomes comprised of DDA and a synthetic
价 格：￥电议型 号：T36357产 地：中国大陆
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T36346Ac-VEID-AMC (ammonium acetate salt)；Ac-VEID-AMC (ammonium acetate salt)Ac-VEID-AMC (ammonium acetate
Ac-VEID-AMC is a fluorogenic substrate based on the caspase-6 cleavage site in lamin A at amino acids VEID during apoptosis.1It has also been reported to be cleaved by related proteases, including caspase-8.2Caspase activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm.
价 格：￥电议型 号：T36346产 地：中国大陆
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T36303Psammaplin A；Psammaplin APsammaplin A
Psammaplin A, a marine metabolite, functions as a robust inhibitor of HDAC and DNA methyltransferases, displaying notable potency and selectivity as a DAC1 inhibitor, with an IC50 value of 0.9 nM. It exhibits antimicrobial effects against Gram-positive bacteria and inhibits both DNA synthesis and DNA gyrase activity, also demonstrating antitumor activity[1][2].
价 格：￥电议型 号：T36303产 地：中国大陆
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T3614Inosine pranobex；异丙肌苷Groprinosin|||Isoprinosine|||Immunovir|||Delimmun；Groprinosin|||Isoprinosine|||
Inosine pranobex (Delimmun) has a number of immunomodulatory effects, including inducing T-lymphocyte differentiation, augmenting macrophage and NK cell functions, and stimulating IL-2 production. Through these effects and others, isoprinosine shows antiviral activity and has applications against subacute sclerosing panencephalitis. It also restores depressed immune responses in Y patients after irradiation and reduces the incidence of infection in leukemia patients undergoing chemotherapy. It i
价 格：￥电议型 号：T3614产 地：中国大陆
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T3606γ-Oryzanol；γ-谷维素Gamma-Oryzanol|||Oliver|||Gammariza；谷维素|||Gamma-Oryzanol|||Oliver|||γ-谷维素|||Gammariz
γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the destruction of free radicals in the skin. It has recently been researched for its ability to slow the progress of melanin pigmentation by intercepting the ultraviolet rays at the skin´s surface and hindering their transmission.
价 格：￥电议型 号：T3606产 地：中国大陆
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T35938D-myo-Inositol-4-phosphate (ammonium salt)；D-myo-Inositol-4-phosphate (ammonium salt)D-myo-Inositol-
D-myo-Inositol-4-phosphate (Ins(4)P1) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-diphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intr
价 格：￥电议型 号：T35938产 地：中国大陆
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T35649EFdA-TP tetraammonium；EFdA-TP tetraammoniumEFdA-TP tetraammonium
EFdA-TP tetraammonium is an influential nucleoside reverse transcriptase (RT) inhibitor that effectively prevents RT-mediated DNA synthesis by acting as an immediate or delayed chain terminator (ICT or DCT). Additionally, EFdA-TP tetraammonium exhibits multiple mechanisms of inhibiting HIV-1 RT[1].
价 格：￥电议型 号：T35649产 地：中国大陆
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T35589Geranyl pyrophosphate triammonium；Geranyl Pyrophosphate (triammonium salt)Geranyl pyrophosphate tria
Geranyl pyrophosphate is an intermediate in the mevalonate pathway. It is formed from dimethylallyl pyrophosphate and isopentenyl pyrophosphate by geranyl pyrophosphate synthase. Geranyl pyrophosphate is used in the biosynthesis of farnesyl pyrophosphate , geranylgeranyl pyrophosphate , cholesterol, terpenes, and terpenoids.
价 格：￥电议型 号：T35589产 地：中国大陆
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T35454γ-Glu-Cys (ammonium salt)；γ-Glu-Cys (ammonium salt)γ-Glu-Cys (ammonium salt)
γ-Glu-Cys is an intermediate in glutathione (GSH) synthesis.1It is formed by ATP-dependent condensation of cysteine and glutamate by γ-glutamylcysteine synthetase. γ-Glu-Cys is also an essential component of phytochelatins, the heavy metal detoxifying enzymes in plants.2
价 格：￥电议型 号：T35454产 地：中国大陆
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T34867Thymoctonan；化合物 T34867Thymic humoral factor gamma 2；Thymic humoral factor gamma 2
Thymoctonan, as a synthetic octapeptide thymic hormone, can repair immunodeficiency of mice cured of plasmacytoma by melphalan.
价 格：￥电议型 号：T34867产 地：中国大陆
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T3485Probimane；化合物ProbimaneAT-2153|||MM-159；AT-2153|||MM-159
Probimane (AT-2153) had Anti-proliferative effects, cell cycle G2/M phase arrest and blocking of chromosome segregation in human tumor cell lines with MST-16.
价 格：￥电议型 号：T3485产 地：中国大陆
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T3475MD 39-AM；化合物MD 39-AMMD 39-AM
Anticytokinin activity was evaluated by 50% of the callus growth on the medium with kinetin but without anti-cytokinin
价 格：￥电议型 号：T3475产 地：中国大陆
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T34692Sphaeropsidin B；化合物 T34692LL S491gamma|||LLS491gamma|||Antibiotic LL-S491gamma|||LL-S491gamma|||Pino
Sphaeropsidin B is a fungal phytotoxin.
价 格：￥电议型 号：T34692产 地：中国大陆
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T34562Scammonin viii；化合物 T34562Scammonin viii
Scammonin viii is a resin glycoside from Convolvulus scammonia.
价 格：￥电议型 号：T34562产 地：中国大陆
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T34561Scammonin VII；化合物 T34561Scammonin VII
Scammonin VII is a resin glycoside from Convolvulus scammonia.
价 格：￥电议型 号：T34561产 地：中国大陆
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T34560Scammonin II；化合物 T34560Scammonin II
Scammonin II is a resin glycoside of radix scammoniae from Convolvulus scammonia.
价 格：￥电议型 号：T34560产 地：中国大陆
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T33535MW01-2-151SRM；化合物 MW01-2-151SRMMW 151|||MW-151|||MW012151SRM|||MW151|||MW01 2 151SRM；MW 151|||MW-151
MW01-2-151SRM is a novel small molecule inhibitor of microglia activation that crosses the blood-brain barrier, has anti-neuroinflammatory effects, attenuates the up-regulation of glial cytokines in models of neuroinflammation, and can be used in studies of traumatic brain injury, Alzheimer´s disease, and alginate toxicity.
价 格：￥电议型 号：T33535产 地：中国大陆
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T33517MTDIA HCl；化合物 T33517MTDIA|||Methylthio-DADMe-Immucillin A|||MT-DADMe-ImmA|||MT-DADMe-ImmA HCl；MTDIA|
MTDIA (MT-DADMe-ImmA and methylthio-DADMe-Immucillin A) is an MTAP inhibitor.
价 格：￥电议型 号：T33517产 地：中国大陆
