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T61934Repinotan；瑞匹诺坦BAY x 3702 free base；BAY x 3702 free base
Repinotan (BAY x 3702 free base) is an orally active and selective 5-HT1A receptor agonist that crosses the blood-brain barrier (BBB), has neuroprotective activity, antagonizes morphine-induced depression of ventilation in anesthetized rats, and can be used in studies of acute ischemic stroke and traumatic brain injury.
价 格：￥电议型 号：T61934产 地：中国大陆
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T6159LY-2584702 free base；化合物LY-2584702LY-2584702 free base
LY2584702 is a selective, ATP-competitive p70S6K inhibitor(IC50: 4 nM).
价 格：￥电议型 号：T6159产 地：中国大陆
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T61572FNDR-20123 free base；化合物 FNDR-20123 free baseFNDR-20123 free base
FNDR-20123 free base, a pioneering and orally administered anti-malarial agent, acts as a Histone Deacetylase (HDAC) inhibitor, displaying potent efficacy with IC50 values of 31 nM for Plasmodium and 3 nM for human HDAC, respectively. It effectively targets both the asexual (IC50=41 nM) and sexual blood stages (IC50=190 nM for male gametocytes) of Plasmodium falciparum. Additionally, FNDR-20123 free base inhibits multiple HDAC isoforms, namely HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8, with respecti
价 格：￥电议型 号：T61572产 地：中国大陆
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T6140SB-334867 free base；化合物SB-334867SB334867A free base|||SB-334867|||SB 334867|||SB334867；SB334867A fre
SB-334867 free base (SB334867A free base) is a selective orexin-1 (OX1) receptor antagonist.
价 格：￥电议型 号：T6140产 地：中国大陆
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T61345LOrbofiban TFA；奥博非班三氟乙酸盐Orbofiban TFA(163250-90-6 Free base)；Orbofiban TFA(163250-90-6 Free base)
Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronary syndromes.
价 格：￥电议型 号：T61345L产 地：中国大陆
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T61231DDO-02005 free base；化合物 DDO-02005 free baseDDO-02005 free base
DDO-02005 (free base), a potent Kv1.5 potassium channel inhibitor, demonstrates an IC 50 of 0.72 μM. It exhibits effective anti-atrial fibrillation (AF) properties in the CaCl2-ACh AF rat model and anti-arrhythmic activity against aconitine-induced arrhythmias [1].
价 格：￥电议型 号：T61231产 地：中国大陆
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T60921LPF-07038124 HCl（2415085-44-6 Free base)；化合物 PF-07038124 HCl（2415085-44-6 Free base)PF-07038124 HCl（2
产品可用于生物细胞实验
价 格：￥电议型 号：T60921L产 地：中国大陆
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T60739LY13g dihydrochloride；化合物 Y13g dihydrochlorideY13g 2HCl(T60739 Free base)；Y13g 2HCl(T60739 Free base)
Y13g dihydrochloride is a potent inhibitor of interleukin 6 (IL-6) and acetylcholinesterase (AChE) (both targets of Alzheimer´s disease (AD) progression are related). Y13g dihydrochloride reverses STZ-induced memory deficits and exhibits histopathology similar to normal animals.
价 格：￥电议型 号：T60739L产 地：中国大陆
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T6072LBGT226；化合物BGT226BGT226 free base|||NVP-BGT226；BGT226 free base|||NVP-BGT226
BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.
价 格：￥电议型 号：T6072L产 地：中国大陆
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T60675LAMPK activator 2 hydrochloride( 2410961-69-0 Free base)；化合物 AMPK activator 2 hydrochloride( 24109
AMPK activator 2 hydrochloride is a fluoroguanidine-containing derivative that up-regulates the AMPK signaling pathway and down-regulates mTOR/4EBP1/p70S6K.AMPK activator 2 hydrochloride inhibits the proliferation and migration of human cancer cell lines (UMUC3, T24, A549).
价 格：￥电议型 号：T60675L产 地：中国大陆
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T60649AV-153 free base；化合物 AV-153 free baseAV-153 free base
AV-153 free base is a 1,4-dihydropyridine (1,4-DHP) derivative. AV-153 free base is an antimutagenic with anti-cancer activity. AV-153 free base interacts with cytosine and thymine and has an influence on poly(ADP)ribosylation. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro [1] [2] [3].
价 格：￥电议型 号：T60649产 地：中国大陆
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T60438LPXS-6302 hydrochloride；化合物PXS-6302盐酸盐PXS-6302 hydrochloride （2584947-54-4 Free base）；PXS-6302 hydroc
PXS-6302 hydrochloride is a potent irreversible lysine oxidase (LOX) inhibitor, inhibiting Bovine LOX, rh LOXL1, rh LOXL2, rh LOXL3, and rh LOXL4 with IC50 of 3.7 μM, 3.4 μM, 0.4 μM, 1.5 μM, and 0.3 μM, respectively. PXS-6302 hydrochloride penetrates easily through the skin and is able to reduce collagen accumulation, significantly improving the appearance of scars.
价 格：￥电议型 号：T60438L产 地：中国大陆
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T60437PNU-282987 free base；化合物 PNU-282987 free basePNU-282987 free base
PNU-282987 (free base) is a potent agonist of α7 nicotinic acetylcholine receptor (nAChR) with an EC50 of 154 nM, which is also a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. PNU-282987 (free base) can be used for the central and peripheral nervous systems study[1].
价 格：￥电议型 号：T60437产 地：中国大陆
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T60405GSK-3036656 free base；化合物 GSK3036656GSK656 HCl|||GSK 3036656|||GSK656|||GSK-3036656|||GSK-656|||GSK
GSK656 (GSK3036656) shows potent inhibition of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS) (IC50 = 0.20 μM) which has potential for the treatment of tuberculosis [1].
价 格：￥电议型 号：T60405产 地：中国大陆
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T60047LV-0219 hydrochloride；V-0219盐酸盐V-0219 hydrochloride（878453-71-5 Free base）；V-0219 hydrochloride（87845
V-0219 hydrochloride, an orally-active positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R), is utilized in obesity-associated diabetes research.
价 格：￥电议型 号：T60047L产 地：中国大陆
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T5862Ezatiostat TFA；化合物Ezatiostat TFATER199(free base)|||Ezatiostat TFA (free base)|||Ezatiostat|||TLK199
Ezatiostat TFA (TLK199) is a liposomal small-molecule glutathione analog inhibitor of glutathione S-transferase (GST) P1-1 with hematopoiesis-stimulating activity.
价 格：￥电议型 号：T5862产 地：中国大陆
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T5677SAR125884 hydrochlorid (1116743-46-4(free base))；化合物SAR125884 hydrochloridSAR125884 hydrochlorid (11
SAR125844 is a potent and selective MET kinase inhibitor with a favorable preclinical toxicity profile,(IC50=4.2 nM).
价 格：￥电议型 号：T5677产 地：中国大陆
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T5465PF-5274857；化合物PF-5274857 freebasePF-5274857 freebase；PF-5274857 freebase
PF-5274857 (PF-5274857 free base) is an effective and selective hedgehog signaling pathway inhibitor (IC50: 5.8 nM and a Ki: 4.6 nM). PF-5274857 is a potentially attractive clinical candidate for the treatment of tumor types including brain tumors and brain metastasis driven by an activated Hh pathway.PF-5274857 was found to effectively penetrate the blood-brain barrier and inhibit Smo activity in the brain of primary medulloblastoma mice, resulting in improved animal survival rates. PF-5274857
价 格：￥电议型 号：T5465产 地：中国大陆
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T5391LBepridil free base；化合物 T5391LCERM1978|||CERM 1978|||Bepadin|||CERM-1978|||Angopril；CERM1978|||CERM 1
Bepridil is a class IV anti-arrhythmic agent and calcium antagonist. Bepridil hydrochloride blocks calcium entry through membranous calcium channels of coronary and peripheral vascular smooth muscle, thereby dilating coronary arteries and peripheral arterioles.
价 格：￥电议型 号：T5391L产 地：中国大陆
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T5351LPU-WS13 hydrobromide；PU-WS13盐酸盐PU-WS13 hydrobromide (1454619-14-7 Free base)；PU-WS13 hydrobromide
PU-WS13 hydrobromide is a GRP94 inhibitor with anti-inflammatory activity and inhibits the proliferation of M2-like macrophages in mouse TNBC tumors.
价 格：￥电议型 号：T5351L产 地：中国大陆
