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T68649Dexlofexidine Free Base；化合物 Dexlofexidine Free BaseDexlofexidine Free Base
Dexlofexidine Free Base is an isomer “+“ of lofexidine, which is an agonist of alpha 2-adrenoceptor, but in 10 times less potent than the other isomer, levlofexidine
价 格：￥电议型 号：T68649产 地：中国大陆
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T68648Diprafenone Free Base；化合物 Diprafenone Free BaseDiprafenone Free Base
Diprafenone Free Base is an antiarrhythmic beta adrenergic antagonist.
价 格：￥电议型 号：T68648产 地：中国大陆
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T68639Ciprostene (free base)；化合物 Ciprostene (free base)Ciprostene (free base)
Ciprostene (free base) is a synthetic, chemically stable analog of prostacyclin (PGI2). In animal models, administration of ciprostene resulted in dose-dependent hypotension, tachycardia, and inhibition of ex vivo ADP-induced platelet aggregation. Ciprostene was evaluated in clinical trials in patients with peripheral vascular disease. It was found to reduce restenosis in patients with coronary artery disease undergoing therapeutic percutaneous transluminal coronary angioplasty.
价 格：￥电议型 号：T68639产 地：中国大陆
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T68599Orphenadrine；邻甲苯海明Orphenadrine (free base)；Orphenadrine (free base)
Orphenadrine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that inhibits clonal HERG channels in a concentration-dependent manner, producing an IC of 0.85 μM in HEK cells.Orphenadrine is an antagonist of central and peripheral muscarinic receptors. Attenuation is blocked by mutations in pore residues Y652 or F656. Orphenadrine has antispasmodic, analgesic, and anticholinergic activity and protects against glutamatergic neurotoxicity in vitro and in vivo.Orphenadrine has inh
价 格：￥电议型 号：T68599产 地：中国大陆
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T68578A-410099.1 free base；化合物 A-410099.1 free baseA-410099.1 free base
A-410099.1 is a novel potent xiap antagonist
价 格：￥电议型 号：T68578产 地：中国大陆
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T68574Tigapotide Free Base；化合物 Tigapotide Free BaseTigapotide Free Base
Tigapotide Free Base is a synthetic peptide corresponding to amino acids 31-45 of PSP94 (prostate secretory protein) that inhibits matrix metalloproteinase-9 secretion.
价 格：￥电议型 号：T68574产 地：中国大陆
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T68561ASP-4000 free base；化合物 ASP-4000 free baseASP-4000 free base
ASP-4000 free base is a dipeptidyl peptidase 4 (DPP) inhibitor with antihyperglycemic activity.
价 格：￥电议型 号：T68561产 地：中国大陆
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T6850LGSK2292767 FA；化合物GSK2292767 FAGSK2292767 FA(1254036-66-2 Free base)；GSK2292767 FA(1254036-66-2 Free
GSK2292767 FA is a potent and selective inhibitor of PI3Kδ (pIC50 : 10.1).GSK2292767 FA is more than 500-fold more selective than other PI3K isoforms.GSK2292767 FA can be used in the study of respiratory diseases.
价 格：￥电议型 号：T6850L产 地：中国大陆
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T68502Dibrospidium Free Base；化合物 Dibrospidium Free BaseDibrospidium Free Base
Dibrospidium Free Base is a dispirotripiperazine derivative and alkylating agent with potential antineoplastic and anti-inflammatory activities. The duration of DNA synthesis inhibition in tumor cells was found to correlate with spirobromine antitumor activity. Spirobromin is superior to prospidin by the power of the anti-inflammatory effect. Spyrobromin can diminish the latent period of the development of tumours in the experimental rats at intraperitoneal administration. At intragastric admini
价 格：￥电议型 号：T68502产 地：中国大陆
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T68483Quinagolide Free Base；化合物 Quinagolide Free BaseQuinagolide Free Base
Quinagolide Free Base is a non-ergot dopamine D(2)-agonist.
价 格：￥电议型 号：T68483产 地：中国大陆
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T68458Fostriecin (free base)；化合物 Fostriecin (free base)Fostriecin (free base)
Fostriecin (free base) is an inhibitor of the serine/threonine protein phosphatases 2A (PP2A) and 4 (PP4) (IC50s = 3.2 and 3 nM, respectively). It less effectively inhibits topoisomerase II and PP1 (IC50s = 40 and 131 μM, respectively) and does not inhibit PP2B. Through its effects on protein phosphatases, fostriecin increases the level of histone H3 phosphorylation and may alter epigenetic regulation of cell proliferation. On a related note, fostriecin was first identified as an antitumor antib
价 格：￥电议型 号：T68458产 地：中国大陆
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T6840LFRAX486 HCL(1232030-35-1 free base)；化合物FRAX486FRAX486 HCL(1232030-35-1 free base)
FRAX486 HCL is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.
价 格：￥电议型 号：T6840L产 地：中国大陆
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T68405KW-2450 free base；化合物 KW-2450 free baseKW-2450 free base
KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free base selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in
价 格：￥电议型 号：T68405产 地：中国大陆
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T68327Dexnafenodone Free Base；化合物 Dexnafenodone Free BaseDexnafenodone Free Base
Dexnafenodone Free Base is a potent inhibitor of noradrenaline, and to a lesser degree of serotonin reuptake, induced changes in the pattern of sleep which are comparable to those of non‐sedating tricyclic antidepressants.
价 格：￥电议型 号：T68327产 地：中国大陆
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T68299MK-7288 free base；化合物 MK-7288 free baseMK-7288 free base
MK-7288 free base is a histamine inverse agonist.
价 格：￥电议型 号：T68299产 地：中国大陆
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T68288OB-24 free base；化合物 OB-24 free baseOB-24 free base
OB-24 free base is a potent and selective heme oxygenase 1 (HO-1) inhibitor.
价 格：￥电议型 号：T68288产 地：中国大陆
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T68246IRC-083927 free base；化合物 IRC-083927 free baseIRC-083927 free base
IRC-083927 free base is novel and potent microtubule inhibitor with potential anticancer activity.
价 格：￥电议型 号：T68246产 地：中国大陆
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T68223GSK-1018921 free base；化合物 GSK-1018921 free baseGSK-1018921 free base
GSK-1018921 free base is a selective GlyT1 inhibitor.
价 格：￥电议型 号：T68223产 地：中国大陆
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T68221Clentiazem (free base)；化合物 Clentiazem (free base)Clentiazem (free base)
Clentiazem (free base) is a calcium channel blocker. It is a chlorine derivative of diltiazem.
价 格：￥电议型 号：T68221产 地：中国大陆
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T68190Carmoxirole (free base)；化合物 Carmoxirole (free base)Carmoxirole (free base)
Carmoxirole (free base) is a dopamine D2 receptor agonist with limited central activity that modulates sympathetic activation and subsequently reduces pre-load and afterload in animals. It was shown, that carmoxirole induced beneficial effects on hemodynamic and neurohumoral parameters in heart failure. In addition, experimental evidence showed that carmoxirole lowered blood pressure in various models of hypertension mainly or exclusively through inhibition of noradrenaline release from sympathe
价 格：￥电议型 号：T68190产 地：中国大陆
