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产品数:86101
参观次数:3737228
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TMS1461Qingyangshengenin BAmyloid-β,Abeta,Inhibitor,Qingyangshengenin B,β-amyloid peptide,inhibit
Qingyangshengenin B is a C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against Aβ toxicity, which decreases Aβ deposition by decreasing the expression of Aβ at the mRNA level. Qingyangshengenin B has antiepileptic and anti-aging effects, it can extend lifespan, increase heat stress-resistance, delay body paralysis, and increase the chemotaxis response in C. elegans models of Alzheimer´s disease. Otophylloside B can suppress the seizure-like locomotor act
价 格:¥电议型 号:TMS1461产 地:中国大陆
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T7111Tenofovir DisoproxilInhibitor,GS-4331,Reverse Transcriptase,Tenofovir Disoproxil,HIV,GS4331,Human im
Tenofovir Disoproxil is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
价 格:¥电议型 号:T7111产 地:中国大陆
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T6852GSK481GSK481,inhibit,Inhibitor,RIPK,GSK-481,RIP kinase,GSK 481,Receptor-interacting protein kinases
GSK481 is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death.
价 格:¥电议型 号:T6852产 地:中国大陆
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T61025GSK-1482160
GSK-1482160 is a CNS-penetrant negative allosteric modulator of P2X7 receptor with oral activity. The P2X7 receptor is involved in the production of pro-inflammatory cytokines by central and peripheral immune cells, so GSK-1482160 has the potential to study inflammatory diseases. GSK-1482160 shows excellent in vitro potency (in functional and electrophysiological assays at recombinant and naive P2X7 receptors across multiple species including humans) and cross-target selectivity.
价 格:¥电议型 号:T61025产 地:中国大陆
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T11492GSK2983559 free acidinhibit,THP-1 cell,RIP kinase,GSK 2983559,GSK2983559 free acid,Inhibitor,GSK-298
GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2). GSK2983559 free acid shows excellent activity in blocking many proinflammatory cytokine responses in human inflammatory bowel disease explant samples an
价 格:¥电议型 号:T11492产 地:中国大陆
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T8820BML-284 hydrochlorideBML284 hydrochloride,AGS,TCF,N-cadherin,Wnt,BML284,cardiac defect,MNK45,BML 284
BML-284 HCL is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.
价 格:¥电议型 号:T8820产 地:中国大陆
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T67837GSK-F1
GSK-F1 is a selective small molecule inhibitor of Type III Phosphatidylinositol 4?Kinase Alpha (PI4KIIIα), pIC50=8.3.
价 格:¥电议型 号:T67837产 地:中国大陆
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T7388GSK805GSK 805,immunity,RAR-related orphan receptor,Inhibitor,GSK805,inhibit,ROR,oral,CNS penetrant,G
GSK805 is a potent, orally bioavailable retinoid-related orphan receptor gamma t (RORγt) inverse agonist that interacts with the receptor´s putative ligand binding domain without exerting significant effects on DNA binding
价 格:¥电议型 号:T7388产 地:中国大陆
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T11471GSK-3β inhibitor 2
GSK-3β inhibitor 2 is a BBB-crossing and selective inhibitor of GSK-3β (IC50 = 1.1 nM). GSK-3β inhibitor 2 can be used in studies about Alzheimer´s disease.
价 格:¥电议型 号:T11471产 地:中国大陆
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T6849UprosertibGSK-2141795,GSK 2141795,Uprosertib,inhibit,Akt,Inhibitor,PKB,Protein kinase B
Uprosertib (GSK2141795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respectively. Phase 2.
价 格:¥电议型 号:T6849产 地:中国大陆
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T39573GSK251GSK251,GSK-251
GSK251 is a highly potent, highly selective, orally bioavailable inhibitor of PI3Kδ with a novel binding mode.
价 格:¥电议型 号:T39573产 地:中国大陆
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T6521GSK 2830371GSK-2830371,Inhibitor,GSK 2830371,Phosphatase,inhibit
GSK2830371 is an orally active, allosteric Wip1 phosphatase inhibitor with IC50 of 6 nM.
价 格:¥电议型 号:T6521产 地:中国大陆
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T9725WAY-119064Inhibitor,Alzheimer’s disease,GSK-3,Glycogen synthase kinase-3,inhibit,Glycogen synthase k
WAY-119064 has skin-whitening, anti-oxidizing and PPAR activities.
价 格:¥电议型 号:T9725产 地:中国大陆
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T39341FCPR03antidepressant-like,FCPR-03,PDE4B1,FCPR 03,PDE4D7,PDE4,neuroprotective,ischemic,FCPR03,AKT,GSK
FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively. FCPR03 has neuroprotective, anti-inflammatory, and antidepressant-like effects.
价 格:¥电议型 号:T39341产 地:中国大陆
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TP1300GsMTx4 TFA (1209500-46-8 free base)GsMTx4 TFA (1209500468 free base),GsMTx4 TFA (1209500 46 8 free b
GsMTx4 TFA is a spider venom peptide that selectively inhibits cationic permeable mechanically-sensitive channels (MSCs) belonging to the Piezo and TRP channel families.
价 格:¥电议型 号:TP1300产 地:中国大陆
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T6854GSK621Apoptosis,CHOP,GSK 621,inhibit,AMP-activated protein kinase,Inhibitor,UPR,PERK,GSK621,Autophag
GSK621 is a specific and potent AMPK activator.
价 格:¥电议型 号:T6854产 地:中国大陆
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T7060Amantadineinhibit,SARS coronavirus,Influenza Virus,antiviral drugs,anticancer,CDK,Bcl-2 Family,hepat
1-Adamantylamine is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake.
价 格:¥电议型 号:T7060产 地:中国大陆
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T7680GSNKGAIIGLM(131602-53-4(free base))GSNKGAIIGLM(131602 53 4(free base)),GSNKGAIIGLM(131602534(free ba
GSNKGAIIGLM is the fragment Aβ(25-35) of the Alzheimer´s amyloid β-peptide.
价 格:¥电议型 号:T7680产 地:中国大陆
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T6659SB 415286inhibit,GSK-3,Inhibitor,Glycogen synthase kinase 3,Glycogen synthase kinase-3,Apoptosis,SB-
SB415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β.
价 格:¥电议型 号:T6659产 地:中国大陆
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T9987WAY-352753synthase,GSK-3,inhibit,WAY 352753,Glycogen synthase kinase 3,WAY352753,Glycogen synthase k
WAY-352753 is a GSK3B-glycogen synthase kinase-3 beta inhibitor.
价 格:¥电议型 号:T9987产 地:中国大陆