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  • T27478GSK3987

    GSK3987 is an LXR ligand. GSK3987 recruits the steroid receptor coactivator-1 to human LXRalpha and LXRbeta with EC50s of 40 nM.

    价 格:¥电议型 号:T27478产 地:中国大陆

  • T27475GSK356278GSK-356278;GSK 356278

    GSK356278 is an effective and selective inhibitor of phosphodiesterase 4 (PDE4), with pIC50s of 8.6, 8.8, and 8.7 for human PDE4A, PDE4B, and PDE4D, respectively. GSK356278 has anti-inflammatory, anxiolytic, and cognition-enhancing effects.

    价 格:¥电议型 号:T27475产 地:中国大陆

  • T2701GSK1292263

    GSK1292263 is a GPR119 agonist and has been investigated for the treatment of DIABETES MELLITUS, TYPE 2.

    价 格:¥电议型 号:T2701产 地:中国大陆

  • T2693AG1024Tyrphostin AG 1024;AGS 200;Tyrphostin

    AG-1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).

    价 格:¥电议型 号:T2693产 地:中国大陆

  • T2682AcalisibCAL-120;GS-9820

    Acalisib (GS-9820) is a potent and selective inhibitor of PI3Kδ.

    价 格:¥电议型 号:T2682产 地:中国大陆

  • T2674GSK0660

    GSK0660 is an antagonist and inverse agonist of PPARβ/δ.

    价 格:¥电议型 号:T2674产 地:中国大陆

  • T2654GSK2656157

    GSK2656157 is a highly specific and ATP-competitive PERK inhibitor (IC50: 0.9 nM) in a cell-free assay. The selectivty is 500-fold higher against a panel of 300 kinases.

    价 格:¥电议型 号:T2654产 地:中国大陆

  • T2633GSK429286ARHO-15

    GSK429286A is a specific inhibitor of ROCK1/2 (IC50: 14/63 nM).

    价 格:¥电议型 号:T2633产 地:中国大陆

  • T2622GSK 650394GSK650394

    GSK650394 is a serum- and glucocorticoid-regulated kinase-1 inhibitor.

    价 格:¥电议型 号:T2622产 地:中国大陆

  • T25465GS143GS 143;GS-143

    GS143 is a selec-tive IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. GS143 sup-presses NF-κB acti-va-tion and tran-scrip-tion of tar-get genes and does not inhibit proteasome activity. GS143 has anti-asthm

    价 格:¥电议型 号:T25465产 地:中国大陆

  • T2436GSK2801

    GSK2801 is an effective, specific and cell active acetyl-lysine competitive inhibitor of BAZ2A(Kd: 136 nM) and BAZ2B(Kd: 257 nM) bromodomains.

    价 格:¥电议型 号:T2436产 地:中国大陆

  • T24111GSK3i XIIIGSK3i-XIII;GSK3 inhibitor XIII;GSK3iXIII

    GSK3i XIII is a GSK-3 ATP-binding site inhibitor.

    价 格:¥电议型 号:T24111产 地:中国大陆

  • T24109GSK329GSK 329;GSK-329

    GSK329 is a moderately selective TNNI3K inhibitor.

    价 格:¥电议型 号:T24109产 地:中国大陆

  • T2409Tenofovir alafenamideGS-7340;替诺福韦艾拉酚胺;替诺福韦

    Tenofovir Alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir.

    价 格:¥电议型 号:T2409产 地:中国大陆

  • T2348GSK2334470

    GSK2334470 is a novel PDK1 inhibitor (IC50: ~10 nM, in a cell-free assay), with no inhibitory at other close related AGC-kinases.

    价 格:¥电议型 号:T2348产 地:中国大陆

  • T2342RaxatrigineCNV-1014802;CNV1014802;GSK-1014802;CNV 1014802

    Raxatrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.

    价 格:¥电议型 号:T2342产 地:中国大陆

  • T2332Elvitegravir埃替格韦;EVG;JTK-303;D06677;GS-9137

    Elvitegravir is a Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor. The mechanism of action of elvitegravir is as an HIV Integrase Inhibitor, and Cytochrome P450 2C9 Inducer.

    价 格:¥电议型 号:T2332产 地:中国大陆

  • T2315GSK-LSD1 dihydrochlorideGSK-LSD1 2HCl

    GSK-LSD1 2HCl is a specificity irreversible LSD1 inhibitor (IC50: 16 nM). The selectivity of GSK-LSD1 for LSD1 is >1000 fold over other closely related FAD utilizing enzymes (i.e. MAO-A, LSD2, MAO-B).

    价 格:¥电议型 号:T2315产 地:中国大陆

  • T22817GSK 789472 hydrochloride1-phenyl-3-(piperidin-2-ylmethyl)imidazolidin-2-one hydrochloride;GSK-789472

    GSK 789472 hydrochloride is both a dopamine D3 receptor antagonist and a D2 partial agonist.

    价 格:¥电议型 号:T22817产 地:中国大陆

  • T22814GSA-10GSA 10

    GSA-10 is a potent Smoothened (Smo) receptor agonist with an EC50 of 1.2 μM. It acts on Smo to promote the differentiation of pluripotent mesenchymal stem cells into osteoblasts. It also mediates Hedgehog (Hh) signaling, which may have research implicatio

    价 格:¥电议型 号:T22814产 地:中国大陆

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