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T78143(R)-VX-11e;化合物 (R)-VX-11e(R)-VX-11e
´(R)-VX-11e (Compound 1) functions as an inhibitor of ERK2 [1].´
价 格:¥电议型 号:T78143产 地:中国大陆
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T77392Pepinemab;派比奈单抗VX 15/2503;VX 15/2503
Pepinemab(VX 15/2503) is a humanized IgG4 monoclonal antibody targeting sematone 4D. Pepinemab has anti-cancer activity and blocks the activity of SEMA4D, which is used to study degenerative diseases similar to Alzheimer´s disease.
价 格:¥电议型 号:T77392产 地:中国大陆
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T72860(R)-Olacaftor;化合物 (R)-Olacaftor(R)-VX-440;(R)-VX-440
(R)-Olacaftor ((R)-VX-440), a Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) modulator, shows promising potential in cystic fibrosis (CF) research.
价 格:¥电议型 号:T72860产 地:中国大陆
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T69552Suzetrigine;化合物SuzetrigineVX-548;VX-548
Suzetrigine(VX-548) is an orally active and specific NaV1.8 inhibitor. Suzetrigine has analgesic activity and can be used to study acute pain and neurotransmission.
价 格:¥电议型 号:T69552产 地:中国大陆
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T67790Biricodar dicitrate;比立考达柠檬酸盐VX 710|||VX 710-3;VX 710|||VX 710-3
Biricodar dicitrate (VX-710) is a potent MDR inhibitor with no anticancer activity and can be used to study prostate cancer.
价 格:¥电议型 号:T67790产 地:中国大陆
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T6729Lomibuvir;化合物LomibuvirVX-222|||VCH-222;VX-222|||VCH-222
Lomibuvir (VCH-222) (VX-222) is a selective, non-nucleoside allosteric inhibitor of HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC 50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than de novo -initiated RNA synthesis [1].
价 格:¥电议型 号:T6729产 地:中国大陆
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T6388Amprenavir;安瑞那韦141W94|||Prozei|||KVX-478|||VX-478;141W94|||安普那韦|||Prozei|||KVX-478|||VX-478|||安瑞那韦
Amprenavir (KVX-478) is a synthetic derivative of hydroxyethylamine sulfonamide that selectively binds to and inhibits human immunodeficiency virus (HIV) protease.
价 格:¥电议型 号:T6388产 地:中国大陆
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T6190Telaprevir;特拉匹韦VX-950|||LY-570310|||Incivek|||MP-424;VX-950|||LY-570310|||Incivek|||MP-424|||特拉匹韦
Telaprevir (Incivek) (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).
价 格:¥电议型 号:T6190产 地:中国大陆
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T6090Belnacasan;化合物BelnacasanVX-765;VX-765
Belnacasan (VX-765) is an IL-converting enzyme (ICE)/caspase-1 inhibitor and an orally bioactive prodrug of VRT-043198. Belnacasan modifies the active site of caspase-1 and leads to caspase-1 blockade, which has been associated with tissue protection against inflammatory diseases in animal models.
价 格:¥电议型 号:T6090产 地:中国大陆
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T6089Neflamapimod化合物NeflamapimodVX-745
Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.
价 格:¥电议型 号:T6089产 地:中国大陆
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T6068MK-5108;化合物MK-5108VX-689|||MK5108;VX-689|||MK5108
MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.
价 格:¥电议型 号:T6068产 地:中国大陆
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T4377Pimodivir;化合物PimodivirVX-787;VX-787
Pimodivir (VX-787), an influenza A virus polymerases inhibitor via oral, interacts with the viral PB2 subunit.
价 格:¥电议型 号:T4377产 地:中国大陆
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T40108Inaxaplin;化合物InaxaplinVX-147;VX-147
Inaxaplin is an apolipoprotein L1 ( APOL1 ) function inhibitor. Inaxaplin can be used for the research of kidney disease.
价 格:¥电议型 号:T40108产 地:中国大陆
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T38801Fobrepodacin;FobrepodacinSPR720|||pVXc-486;SPR720|||pVXc-486
Fobrepodacin (SPR720) is an orally active and potent phosphate prodrug of SPR719 (VXc-486). Fobrepodacin has potent bactericidal activities in vivo.
价 格:¥电议型 号:T38801产 地:中国大陆
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T3444Merimepodib;美泊地布VX-497|||VI-21497;美泊地布|||VX-497|||VI-21497
Merimepodib (VX-497) is a novel noncompetitive inhibitor of Inosine monophosphate dehydrogenase(IMPDH).
价 格:¥电议型 号:T3444产 地:中国大陆
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T33243MC-Val-Cit-PAB-VX765;化合物 T33243MC-Val-Cit-PAB-VX-765|||MCValCitPABVX765|||MC Val Cit PAB VX765|||VX7
MC-VAL-CIT-PAB-VX765 or MC-VAL-CIT-PABC-VX765 is a VX765 derivative that can be conjugated to antibodies, proteins, or polymers for targeted drug delivery. MC-Val- CIT -PAB is a cathepsin cleavable ADC connector, which has been widely used in the preparation of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T33243产 地:中国大陆
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T3166VX-11e;化合物VX-11eVertex-11e|||VTX-11e|||TCS ERK 11e;Vertex-11e|||VTX-11e|||TCS ERK 11e
VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.
价 格:¥电议型 号:T3166产 地:中国大陆
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T31123cvxIAA;化合物 T31123convex IAA|||5-(3-MeOPh)-IAA;convex IAA|||5-(3-MeOPh)-IAA
cvxIAA is an orthogonal auxin-TIR1 receptor pair. cvxIAA triggers auxin signaling without interfering with endogenous auxin or TIR1/AFBs. cvxIAA hijacked the downstream auxin signaling in vivo both at the transcriptomic level and in specific developmental contexts, only in the presence of a complementary, concave TIR1 (ccvTIR1) receptor. cvxIAA-ccvTIR1 system serves as a powerful tool for solving outstanding questions in auxin biology and for precise manipulation of auxin-mediated processes as a
价 格:¥电议型 号:T31123产 地:中国大陆
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T30293Bamocaftor;化合物BamocaftorVX-659;VX-659
Bamocaftor is a CFTR channel (DeltaF508-CFTR mutation) corrector for CF transmembrane conductance regulators designed to restore F508del-CFTR protein function. Combined use of tezacaftor and VX-561 for the treatment of cystic fibrosis patients with F508del/MF.
价 格:¥电议型 号:T30293产 地:中国大陆
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T29149VX 759;化合物 T29149VCH759|||BCH27759|||VX-759|||VX759|||VCH-759|||BCH-27759;VCH759|||BCH27759|||VX-759
VX 759, a nonstructural protein 5B (NS5B) inhibitor, is used potentially for the treatment of HCV infection.
价 格:¥电议型 号:T29149产 地:中国大陆