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T28628RVX-297;化合物RVX-297RVX297;RVX297
RVX-297 is a BD2 selective inhibitor of BET bromodomains. RVX-297 preferentially binds to the BD2 domains of the BET bromodomain and Extra Terminal (BET) family of protein.
价 格:¥电议型 号:T28628产 地:中国大陆
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T26693AVX-001;化合物 T26693FP-025|||AKH-217|||AKH217|||AVX001|||FP025;FP-025|||AKH-217|||AKH217|||AVX001|||FP
AVX-001, a cytosolic phospholipase A2 (cPLA2) inhibitor, is used potentially for the treatment of psoriasis.
价 格:¥电议型 号:T26693产 地:中国大陆
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T2669Berzosertib;化合物BerzosertibVX-970|||VE-822;VX-970|||VE-822
Berzosertib (VE-822) has been used in trials studying the treatment of Ovarian Neoplasms, Ovarian Serous Tumor, Adult Solid Neoplasm, Advanced Solid Tumor, and Advanced Solid Neoplasm, among others.
价 格:¥电议型 号:T2669产 地:中国大陆
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T2636Decernotinib;化合物DecernotinibVX-509|||VRT-831509;VX-509|||VRT-831509
Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.
价 格:¥电议型 号:T2636产 地:中国大陆
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T26186Sermetacin;化合物 T26186Sermetacina|||SH G 318 AB|||SHG 318 AB|||TVX 3158;Sermetacina|||SH G 318 AB|||S
Sermetacin is an anti-inflammatory agent.
价 格:¥电议型 号:T26186产 地:中国大陆
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T2595Lumacaftor;鲁玛卡托VX-809|||VRT 826809;鲁玛卡托|||VX-809|||VRT 826809
Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. It enhances F508del-CFTR protein maturation in FRT cells (EC50: 100 nM).
价 格:¥电议型 号:T2595产 地:中国大陆
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T25898Olacaftor;化合物 T25898VX 440|||VX-440|||VX440;VX 440|||VX-440|||VX440
Olacaftor, also known as VX-440, is a protein modulator of cystic fibrosis transmembrane regulator (CFTR).
价 格:¥电议型 号:T25898产 地:中国大陆
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T2588Ivacaftor;依伐卡托Ivacaftor (VX-770)|||VX-770;Ivacaftor (VX-770)|||VX-770|||依伐卡托
Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells, respectively.
价 格:¥电议型 号:T2588产 地:中国大陆
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T2513VX-702;化合物VX-702VX-702
VX-702 is a highly specific p38α MAPK inhibitor, 14-fold higher selectivity for the p38α than p38β. VX-702 is a small molecule investigational oral anti-cytokine therapy for treatment of inflammatory diseases, specifically rheumatoid arthritis (RA).
价 格:¥电议型 号:T2513产 地:中国大陆
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T2509Tozasertib;化合物TozasertibMK-0457|||VX 680;MK-0457|||VX 680
Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C). It shows selectivity against more than 190 different kinases.
价 格:¥电议型 号:T2509产 地:中国大陆
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T2480Apabetalone;阿帕他隆RVX-208|||RVX000222;RVX-208|||RVX000222|||阿帕他隆
Apabetalone (RVX000222) , an effective BET bromodomain inhibitor, has been investigated for the treatment of diabetes, atherosclerosis, and coronary artery disease.
价 格:¥电议型 号:T2480产 地:中国大陆
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T2438HMN-214;化合物HMN214IVX-214|||HMN214;IVX-214|||HMN214
HMN-214 (IVX-214) is a potent PLK1 inhibitor with an average IC50 of 0.12 μM.
价 格:¥电议型 号:T2438产 地:中国大陆
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T23960Dacuronium;化合物 T23960UNII-VD6L56ZVX1|||17-Hydroxypancuronium|||Androstane, piperidinium deriv;UNII-V
Dacuronium is a new steroidal drug of neuromuscular blocking properties. Dacuronium produced a competitive type of neuromuscular block with a potency of approximately one-tenth that of tubocurarine and one-fiftieth that of pancuronium.
价 格:¥电议型 号:T23960产 地:中国大陆
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T2263Tezacaftor;化合物VX661VX661;VX661|||1-(2,2-二氟-1,3-苯并二氧戊环-5-基)-N-[1-[(2R)-2,3-二羟基丙基]-6-氟-2-(2-羟基-1,1-二甲基
Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.
价 格:¥电议型 号:T2263产 地:中国大陆
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T1979AVN-944;化合物AVN944VX-944;VX-944
AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.
价 格:¥电议型 号:T1979产 地:中国大陆
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T19532Fobrepodacin disodium;化合物 T19532pVXc-486 disodium|||SPR720 disodium;pVXc-486 disodium|||SPR720 disod
SPR720 disodium is an orally active and potent phosphate VXc-486 prodrug,has potent bactericidal activities in vivo.
价 格:¥电议型 号:T19532产 地:中国大陆
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T16570Pralnacasan;化合物 T16570VX-740|||HMR 3480;VX-740|||HMR 3480
Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ. Pralnacasan is an effective, non-peptide, and orally active interleukin-1β converting enzyme inhibitor (Ki: 1.4 nM). Pralnacasan has the potential for osteoarthritis and rheumatoid arthritis treatment.
价 格:¥电议型 号:T16570产 地:中国大陆
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T16368NVX-207;化合物 T16368NVX-207
NVX-207 is a derivative of betulinic acid. It has anti-cancer activity.
价 格:¥电议型 号:T16368产 地:中国大陆
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T14935Elexacaftor;化合物ElexacaftorVX-445;VX-445
Elexacaftor (VX-445) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR) and it also facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface.
价 格:¥电议型 号:T14935产 地:中国大陆
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T1467Acemetacin阿西美辛阿西美辛|||K-708|||TVX 1322
Acemetacin (TVX 1322) is a carboxymethyl ester of indometacin. It is a potent non-steroidal anti-inflammatory drug, derived from the indol-3-acetic acid, whose activity is thought to be mainly through its active metabolite indomethacin. In clinical trials, acemetacin exhibits a better gastric tolerability compared to its active metabolite indometacin.
价 格:¥电议型 号:T1467产 地:中国大陆