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T82221Head activator neuropeptide；化合物 Head activator neuropeptideHead activator neuropeptide
Head activator neuropeptide, a mitogen for neuronal or neuroendocrine mammalian cell lines, induces mitosis by signaling through GPR37 binding [1].
价 格：￥电议型 号：T82221产 地：中国大陆
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T81446PKM2 activator 6；化合物 PKM2 activator 6PKM2 activator 6
Compound Z10 (PKM2 activator 6) serves as both a PKM2 activator and a PDK1 inhibitor, exhibiting dissociation constants (K D ) of 121 μM and 19.6 μM, respectively. It promotes apoptosis in colorectal cells while suppressing their proliferation and migration, additionally inhibiting glycolysis. Compound Z10 demonstrates inhibitory effects on the proliferation of various cell lines, including DLD-1, HCT-8, HT-29, and MCF-10A, with half-maximal inhibitory concentrations (IC 50 ) of 10.04 μM, 2.16 μ
价 格：￥电议型 号：T81446产 地：中国大陆
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T81237RyRs activator 4；化合物 RyRs activator 4RyRs activator 4
Compound B18 (RyRs activator 4) is an insect ryanodine receptor activator that exhibits larvicidal activity against Mythimna separata with an LC50 value of 1.32 mg/L [1].
价 格：￥电议型 号：T81237产 地：中国大陆
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T81236RyRs activator 5；化合物 RyRs activator 5RyRs activator 5
Compound A-1 (RyRs activator 5) is an efficacious agonist of ryanodine receptors, exhibiting activity against Spodoptera frugiperda [1].
价 格：￥电议型 号：T81236产 地：中国大陆
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T81154SIRT1 activator 1；化合物 SIRT1 activator 1SIRT1 activator 1
SIRT1 Activator 1 (Compound 3), a marine-derived xyloallenoide A derivative from the Xylaria sp. mangrove fungus, exhibits angiogenic effects in zebrafish and protects human endothelial progenitor cells (hEPCs) from AngII-induced senescence. It achieves this by elevating SIRT1 expression and modulating the AMPK/Akt signaling pathway [1].
价 格：￥电议型 号：T81154产 地：中国大陆
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T8055TFEB activator 1；化合物TFEB activator 1(1E,4E)-1,5-Bis(2-Methoxyphenyl)penta-1,|||Curcumin analog compo
TFEB activator 1 (Curcumin analog compound C1) is an activator of transcription factor EB (TFEB) with promise for the prevention or treatment of Alzheimer´s disease.
价 格：￥电议型 号：T8055产 地：中国大陆
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T79743Caspase-3 activator 1；化合物 Caspase-3 activator 1Caspase-3 activator 1
Caspase-3 activator 1 (compound 4b), a Ru(III) metal complex, effectively inhibits gastric tumor growth and metastasis by mediating caspase-3 cleavage. This cleavage enables Caspase-3 to process gasdermin E (GSDME), which results in the production of the GSDME-N terminus, leading to perforation of the gastric tumor cell membrane. Furthermore, compound 4b induces pyroptosis and subsequent immune responses. It can be incorporated with decitabine (DCT) into the 4b-DCT-Lip lipid delivery system [1].
价 格：￥电议型 号：T79743产 地：中国大陆
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T79703RyRs activator 3；化合物 RyRs activator 3RyRs activator 3
RyRs activator 3 (compound A4) serves as an insecticide highly effective against both the diamondback moths, M. separata and P. xylostella. It exhibits an LC50 of 3.27 mg/L for controlling diamondback moth populations. The mechanism of action involves binding to the ryanodine receptor, which elevates cytoplasmic Ca2+ concentration, resulting in biological toxicity [1].
价 格：￥电议型 号：T79703产 地：中国大陆
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T79702Nrf2 activator-9；化合物 Nrf2 activator-9Nrf2 activator-9
Nrf2 activator-9 (compound D-36) is an agent that mitigates oxidative stress by inhibiting the apoptosis of HUVEC cells induced by oxidized low-density lipoprotein (oxLDL) and high glucose (HG). It also protects vascular endothelial cells (VEC) from oxLDL and HG-induced injury, offering potential therapeutic benefits for the prevention and treatment of atherosclerosis [1].
价 格：￥电议型 号：T79702产 地：中国大陆
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T79484Nrf2 activator-8；化合物 Nrf2 activator-8Nrf2 activator-8
Nrf2 Activator-8 (Compound 10e), with an EC50 of 37.9 nM, is a potent Nrf2 activator that demonstrates significant antioxidant and anti-inflammatory properties in BV-2 microglial cells. Furthermore, this compound notably ameliorates spatial memory deficits in a mouse model of lipopolysaccharide (LPS)-induced neuroinflammation [1].
价 格：￥电议型 号：T79484产 地：中国大陆
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T79226AMPK activator 11；化合物 AMPK activator 11AMPK activator 11
AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-activated protein kinase (AMPK) and enhancement of oxidative phosphorylation (OXPHOS) (mitochondrial metabolism). This compound demonstrates particular efficacy in inhibiting RKO xenograft growth, rendering it useful for anti-tumor and metabolic disease research [1].
价 格：￥电议型 号：T79226产 地：中国大陆
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T78791AMPK activator 12；AMPK 激活剂12AMPK activator 12
AMPK activator 12 is an AMPK activator and GDF15 inducer that elevates the expression level of GDF15 protein in human hepatocytes, which can be used for cancer research.
价 格：￥电议型 号：T78791产 地：中国大陆
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T78696Nrf2 activator-7；化合物 Nrf2 activator-7Nrf2 activator-7
Nrf2 Activator-7 (Compound 12b) effectively enhances the Nrf2 signaling pathway as a potent Nrf2 activator.
价 格：￥电议型 号：T78696产 地：中国大陆
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T78650Nrf2 activator-3；Nrf2 激活剂3Nrf2 activator-3
Nrf2 activator-3 is a potent Nrf2 activator with potential anti-inflammatory, antioxidant and anti-tumor activity, which can be used to study neurological and immune-related diseases.
价 格：￥电议型 号：T78650产 地：中国大陆
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T77616VU533；化合物VU533Nape-Pld activator；Nape-Pld activator
VU533 (Nape-Pld activator) is a NAPE-PLD activator with an EC50 value of 0.30 ?M.VU533 enhances NAPE-PLD activity and increases macrophage cytosolic burial.VU533 may be used in diseases associated with cardiometabolism.
价 格：￥电议型 号：T77616产 地：中国大陆
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T77349CCR1/5/8 activator 1；化合物 CCR1/5/8 activator 1CCR1/5/8 activator 1
CCR1/5/8 activator 1 is a cytoplasmic phospholipase A inhibitor with antifungal activity.
价 格：￥电议型 号：T77349产 地：中国大陆
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T7674Thrombin Receptor Activator for Peptide；化合物T7674Thrombin Receptor Activator for Peptide
Thrombin Receptor Activator for Peptide is also called Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), used in the research of coronary heart disease (CHD).
价 格：￥电议型 号：T7674产 地：中国大陆
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T7625TRAP-6；化合物TRAP-6(2TFA)PAR-1 agonist peptide|||Thrombin Receptor Activator Peptide 6|||TRAP-6(2TFA)；P
TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1).
价 格：￥电议型 号：T7625产 地：中国大陆
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T75132PKR activator 4；化合物 PKR activator 4PKR activator 4
PKR activator 4 (example 7A), a potent activator of pyruvate kinase R (PKR), holds promise for blood disorder research [1].
价 格：￥电议型 号：T75132产 地：中国大陆
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T7496Thrombin Receptor Activator for Peptide 5 (TRAP-5)；化合物T7496Thrombin Receptor Activator for Peptide；T
Thrombin Receptor Activator for Peptide 5 (TRAP-5), also known as Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), is employed in coronary heart disease (CHD) research.
价 格：￥电议型 号：T7496产 地：中国大陆
