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T61496NPR-C activator 1；化合物 NPR-C activator 1NPR-C activator 1
NPR-C activator 1 (Compound 1) is a potent activator of natriuretic peptide receptor C (NPR-C), a receptor involved in the regulation of vascular homeostasis. It acts as a potent agonist (EC50 ~ 1 μM) of C-type natriuretic peptide (CNP), showing promising in vivo pharmacokinetic properties [1].
价 格：￥电议型 号：T61496产 地：中国大陆
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T61369p53 Activator 2；化合物 p53 Activator 2p53 Activator 2
p53 Activator 2 (compound 10ah) intercalates into DNA, causing significant DNA double-strand breaks and upregulates the expression of p53, p-p53, CDK4, and p21, leading to cell cycle arrest at the G2/M phase. It induces apoptosis, significantly reduces the expression of anti-apoptosis proteins Bcl-2, Bcl-xL, and cyclin B1 levels, and exhibits anti-proliferative activity against MGC-803 cells with an IC50 of 1.73 μM. Furthermore, p53 Activator 2 demonstrates potent anticancer effectiveness in MGC
价 格：￥电议型 号：T61369产 地：中国大陆
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T61205Nrf2/HO-1 activator 1；化合物 Nrf2/HO-1 activator 1Nrf2/HO-1 activator 1
Nrf2/HO-1 activator 1 (Compound 24) is a potent neuroprotective agent with significant antioxidant activities, specifically targeting Nrf2/HO-1. It is particularly useful in Parkinson´s disease (PD) research, illustrating its potential in therapeutic applications [1].
价 格：￥电议型 号：T61205产 地：中国大陆
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T60675LAMPK activator 2 hydrochloride( 2410961-69-0 Free base)；化合物 AMPK activator 2 hydrochloride( 24109
AMPK activator 2 hydrochloride is a fluoroguanidine-containing derivative that up-regulates the AMPK signaling pathway and down-regulates mTOR/4EBP1/p70S6K.AMPK activator 2 hydrochloride inhibits the proliferation and migration of human cancer cell lines (UMUC3, T24, A549).
价 格：￥电议型 号：T60675L产 地：中国大陆
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T60675AMPK activator 2；AMPK激活剂2AMPK activator 2
AMPK activator 2 is a chloroformin derivative with potential anticancer activity, which can up-regulate AMPK signaling pathway and down-regulate mTOR/4EBP1/p70S6K, and inhibit proliferation and migration of human cancer cell lines (UMUC3, T24, A549).
价 格：￥电议型 号：T60675产 地：中国大陆
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T60533Nln activator 1；化合物 Nln activator 1Nln activator 1
Nln activator 1 is a first-in-class activator of peptidomimetic neurolysin with enhanced brain penetration and stability.
价 格：￥电议型 号：T60533产 地：中国大陆
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T4280Gcase activator 1；化合物LTI291LTI-291|||LTI 291|||LTI291；LTI-291|||LTI 291|||LTI291
Gcase activator 1 (LTI-291) is a glucocerebrosidase (Gcase) activator.
价 格：￥电议型 号：T4280产 地：中国大陆
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T39965NF-κΒ activator 1；化合物NF-κΒ activator 1NF-κΒ activator 1
NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns. NF-κΒ is widely used in eukaryotic cells as a gene regulating cell proliferation and cell survival. NF-κΒ activator 1 induces superoxide dismutase (SOD) 2 1 mRNA expression.
价 格：￥电议型 号：T39965产 地：中国大陆
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T39924NF-κΒ activator 2；化合物NF-κΒ activator 2NF-κΒ activator 2
NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an EC50 value of 1.58 μM. By enhancing NF-κB expression and activation, it induces SOD 2 synthesis, rendering it useful for amyotrophic lateral sclerosis (ALS) research [1].
价 格：￥电议型 号：T39924产 地：中国大陆
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T39719Nrf2 activator-1；Nrf2激动剂1Nrf2 activator-1；Nrf2 activator-1
Nrf2 activator-1 is a potent activator of NF-E2-related factor 2 (Nrf2).Nrf2 activator-1 can be used to study COPD and other respiratory diseases including asthma, acute lung injury (ALI), acute respiratory distress syndrome (ARDS), and pulmonary fibrosis.
价 格：￥电议型 号：T39719产 地：中国大陆
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T36935PKUMDL-LC-101-D04；化合物PKUMDL-LC-101-D04GPX4-Activator-1d4|||PKUMDL-LC-101-D04；GPX4-Activator-1d4|||PK
PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4), a regulator of iron death. GPX4 activity was increased to 150% of control levels when used at a concentration of 20 μM in a cell-free assay, and at a concentration of 61 μM in wild-type, but not Gpx4-/-, mouse embryonic fibroblast (MEF) extracts.PKUMDL-LC-101-D04 (200 μM) reduced cholesterol peroxide-induced MEF death.
价 格：￥电议型 号：T36935产 地：中国大陆
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T3293Apoptozole；化合物ApoptozoleApoptosis Activator VII；Apoptosis Activator VII
Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.
价 格：￥电议型 号：T3293产 地：中国大陆
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T28788SK-216；化合物 T28788SK216.Plasminogen activator inhibitor-1 (PAI-1) inhibitor；SK216.Plasminogen activat
SK-216 is a specific PAI-1 inhibitor. SK-216 reduced the extent of angiogenesis in the tumors and inhibited VEGF-induced migration and tube formation by human umbilical vein endothelial cells in vitro. SK-216 reduced the degree of bleomycin-induced pulmonary fibrosis in mice.
价 格：￥电议型 号：T28788产 地：中国大陆
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T28095MrgX1-Activator-1；化合物 T28095MrgX1-Activator-1
MrgX1-Activator-1 is a MrgX1 receptor activator.
价 格：￥电议型 号：T28095产 地：中国大陆
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T24791SIRT1-A2；化合物 T24791SIRT1-Activator-A2|||SIRT1A2|||SIRT1 Activator A2；SIRT1-Activator-A2|||SIRT1A2|||
SIRT1-A2 is a SIRT1 activator.
价 格：￥电议型 号：T24791产 地：中国大陆
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T24546Nrf2-Activator-12G；化合物 T24546Nrf2 Activator IV|||Nrf2 Activator-IV；Nrf2 Activator IV|||Nrf2 Activato
Nrf2-Activator-12G is a potent Nrf-2 activator.
价 格：￥电议型 号：T24546产 地：中国大陆
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T23828BtGH84 Activator I；化合物 T238284-EtOQz|||BtGH-84 Activator I|||4 EtOQz|||4EtOQz|||Bt-GH-84 Activator I
BtGH84 Activator I is a BtGH84 activator. It is the small molecule activator of a glycoside hydrolase.
价 格：￥电议型 号：T23828产 地：中国大陆
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T23686AHR-activator-1023；化合物 T23686Branching Morphogenesis Modulator 1023|||Cpd 1023|||Compound 1023|||BMM
AHR-activator-1023 is the aryl hydrocarbon receptor activator. It is also a specific FGF2-induced branching morphogenesis modulator.
价 格：￥电议型 号：T23686产 地：中国大陆
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T22980MIRA-1；化合物MIRA-1p53 Activator VIII|||1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2,5-dione|||(2,5-dioxo-2,5-
MIRA-1 (WRN Helicase Inhibitor) is a restorer of wild-type p53 conformation/cellular function and selectively inhibits Werner syndrome WRN helicase activity with an IC50 of 20 ?M.
价 格：￥电议型 号：T22980产 地：中国大陆
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