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T80661Antihypertensive sulfonanilide XVII;抗高血压剂XVIIAntihypertensive sulfonanilide XVII
Antihypertensive sulfonanilide XVII is an orally available antihypertensive sulfonanilide small molecule compound for the study of hypertension.
价 格:¥电议型 号:T80661产 地:中国大陆
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T80618Narlumosbart;化合物 NarlumosbartNarlumosbart
Narlumosbart (JMT103) is an IgG4κ monoclonal antibody that selectively binds to the receptor activator of nuclear factor-κB ligand (RANKL)[1].
价 格:¥电议型 号:T80618产 地:中国大陆
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T80606Duvortuxizumab;化合物 DuvortuxizumabMGD 011;MGD 011
Duvortuxizumab (MGD 011) is a chimeric, humanized immunoglobulin (IG) antibody that specifically targets CD19 and CD3E receptors [1].
价 格:¥电议型 号:T80606产 地:中国大陆
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T80593Brolucizumab;化合物 BrolucizumabDLX1008|||ESBA 1008|||RTH258;DLX1008|||ESBA 1008|||RTH258
Brolucizumab (DLX1008) is a single-chain anti-VEGF-A antibody fragment exhibiting low picomolar affinity (K D = 1.05 pM), utilized for cancer research [1] [2].
价 格:¥电议型 号:T80593产 地:中国大陆
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T80578Evunzekibart;化合物 EvunzekibartATOR-1017;ATOR-1017
Evunzekibart (ATOR-1017) is an Fc-γ receptor-dependent 4-1BB agonist and an IgG4 isotype antibody. It can function as a monotherapy or synergize with anti-PD1 therapies to promote anti-tumor effects.
价 格:¥电议型 号:T80578产 地:中国大陆
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T80577Varokibart;化合物 VarokibartVarokibart
Varokibart (TEV-53275) is a human IgG4λ antibody that targets interleukin-5 (IL-5) [1].
价 格:¥电议型 号:T80577产 地:中国大陆
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T80576Picankibart;化合物 PicankibartPicankibart
Picankibart is a mouse-origin monoclonal antibody (IgG1κ) that targets interleukin 23A (IL23A) [1].
价 格:¥电议型 号:T80576产 地:中国大陆
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T80575Simaravibart;化合物 SimaravibartMAD-0004J08;MAD-0004J08
Simaravibart (MAD-0004J08), an IgG1κ monoclonal antibody, specifically targets the receptor-binding domain of the SARS-CoV-2 spike (S) glycoprotein [1].
价 格:¥电议型 号:T80575产 地:中国大陆
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T80572Exlinkibart;化合物 ExlinkibartLVGN-6051;LVGN-6051
Exlinkibart (LVGN-6051) is a humanized IgG1κ antibody that selectively targets TNFRSF9, utilizing complementarity-determining region (CDR) grafting technology for its humanization.
价 格:¥电议型 号:T80572产 地:中国大陆
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T80571Eurestobart;化合物 EurestobartEurestobart
Eurestobart is a humanized IgG1κ (IgG1 kappa) monoclonal antibody that specifically targets the enzyme ectonucleoside triphosphate diphosphohydrolase (ENTPDase).
价 格:¥电议型 号:T80571产 地:中国大陆
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T80570Dazukibart;化合物 DazukibartDazukibart
Dazukibart is a humanized IgG1κ monoclonal antibody of murine origin, specifically targeting interferon beta 1 (IFNB1) [1].
价 格:¥电议型 号:T80570产 地:中国大陆
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T80566Temtokibart;化合物 TemtokibartTemtokibart
Temtokibart is a humanized IgG1 λ2 antibody that specifically targets IL22RA1, and is expressed by cells that are deficient in the glutamine synthetase gene.
价 格:¥电议型 号:T80566产 地:中国大陆
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T80564Vamikibart;化合物 VamikibartVamikibart
Vamikibart is a chimeric, humanized IgG2κ antibody that targets IL6 [1].
价 格:¥电议型 号:T80564产 地:中国大陆
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T80560Tulisokibart;化合物 TulisokibartPRA-023|||PRA023;PRA-023|||PRA023
Tulisokibart (PRA023) is a humanized IgG1-κ monoclonal antibody that targets TNFSF15/TL1A, with potential applications in researching various inflammatory and fibrotic diseases, including Crohn´s Disease (CD) [1] [2].
价 格:¥电议型 号:T80560产 地:中国大陆
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T80550N-myristoyl-RKRTLRRL;化合物 N-myristoyl-RKRTLRRLN-myristoyl-RKRTLRRL
N-myristoyl-RKRTLRRL is a compound that impedes the binding of protein kinase C (PKC) substrates and inhibits calcium (Ca2+)- and phosphatidylserine (PS)-dependent phosphorylation of histones, exhibiting an IC50 of 5 μM. Additionally, it demonstrates an inhibitory effect on histone phosphorylation with an IC50 of 80 μM [1] [2].
价 格:¥电议型 号:T80550产 地:中国大陆
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T80510Tertiapin-RQ;化合物 Tertiapin-RQTertiapin-RQ
Tertiapin-RQ, an inward rectifier potassium (K+) channel-blocking peptide, exhibits antidepressant effects [1].
价 格:¥电议型 号:T80510产 地:中国大陆
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T80496Kurtoxin;化合物 KurtoxinKurtoxin
Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor, exhibiting a dissociation constant (Kd) of 15 nM for the Cav3.1 (α1G T-type) Ca2+ channel. The compound demonstrates high-affinity interactions with native neuronal high-threshold L-type, N-type, and P-type Ca2+ channels in both central and peripheral neurons, while also displaying cross-reactivity with the voltage-gated Na+ channel [1].
价 格:¥电议型 号:T80496产 地:中国大陆
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T80494Tap1a;化合物 Tap1aTRTX-Tap1a|||Theraphotoxin-Tap1a|||?/ω-TRTX-Tap1a;TRTX-Tap1a|||Theraphotoxin-Tap1a|||
Theraphotoxin-Tap1a (Tap1a) is a spider venom-derived peptide that acts as an inhibitor of sodium channels, displaying IC50 values of 80 nM for Na v 1.7 and 301 nM for Na v 1.1. It demonstrates analgesic effects [1].
价 格:¥电议型 号:T80494产 地:中国大陆
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T80452Ceratotoxin-1;化合物 Ceratotoxin-1CcoTx1|||β-TRTX-cm1a;CcoTx1|||β-TRTX-cm1a
Ceratotoxin-1 (CcoTx1) is a peptide toxin that functions as an inhibitor of various voltage-gated sodium channel subtypes. It selectively inhibits Nav1.1/β1, Nav1.2/β1, Nav1.4/β1, and Nav1.5/β1 with IC50 values of 523 nM, 3 nM, 888 nM, and 323 nM, respectively. Additionally, Ceratotoxin-1 is known to inhibit Nav1.8/β1 [1].
价 格:¥电议型 号:T80452产 地:中国大陆
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T80451Ceratotoxin-2;化合物 Ceratotoxin-2CcoTx2|||β-TRTX-cm1b;CcoTx2|||β-TRTX-cm1b
Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel inhibitor, demonstrating half maximal inhibitory concentrations (IC50) of 8 nM for Na v 1.2/β 1 and 88 nM for Na v 1.3/β 1 [1].
价 格:¥电议型 号:T80451产 地:中国大陆