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  • T80450Pe1b；化合物 Pe1bμ-TrTx-Pe1b；μ-TrTx-Pe1b

    Pe1b (μ-TrTx-Pe1b) is a selective inhibitor of the NaV1.7 channel, exhibiting an inhibitory concentration 50 (IC50) value of 167 nanomolar (nM) [1].

    价 格：￥电议型 号：T80450产 地：中国大陆

  • T80445Phlo1a；化合物 Phlo1aμ-TrTx-Phlo1a；μ-TrTx-Phlo1a

    Phlo1a (μ-TrTx-Phlo1a), a 35-amino acid peptide toxin, demonstrates a weak inhibitory effect on Nav1.2 and Nav1.5 channels [1]. Meanwhile, Phlo1b acts as a selective inhibitor of the Nav1.7 channel.

    价 格：￥电议型 号：T80445产 地：中国大陆

  • T80444Phlo1b；化合物 Phlo1bμ-TrTx-Phlo1b；μ-TrTx-Phlo1b

    Phlo1b (μ-TrTx-Phlo1b), a 35-amino acid peptide toxin, selectively inhibits Nav1.7 channels with minimal inhibition of Nav1.2 and Nav1.5 [1].

    价 格：￥电议型 号：T80444产 地：中国大陆

  • T80437μ-TRTX-Hd1a；化合物 μ-TRTX-Hd1aμ-TRTX-Hd1a

    μ-TRTX-Hd1a, a spider venom-derived compound, selectively inhibits the human NaV 1.7 channel by functioning as a gating modifier. It interacts with the S3b-S4 paddle motif within domain II of the channel [1].

    价 格：￥电议型 号：T80437产 地：中国大陆

  • T80429π-TRTX-Hm3a；化合物 π-TRTX-Hm3aπ-TRTX-Hm3a

    π-TRTX-Hm3a, a 37-amino acid peptide derived from the venom of the Togo starburst tarantula (Heteroscodra maculata), selectively inhibits the acid-sensing ion channel 1a (ASIC1a) in a pH-dependent manner, with an inhibitory concentration half-max (IC50) of 1-2 nM, and also potentiates the activity of acid-sensing ion channel 1b (ASIC1b) with an effective concentration half-max (EC50) of 46.5 nM [1].

    价 格：￥电议型 号：T80429产 地：中国大陆

  • T80272Vicatertide；化合物 VicatertideSB-01；SB-01

    Vicatertide is an inhibitor of transforming growth factor beta-1 (TGF-β1) [1].

    价 格：￥电议型 号：T80272产 地：中国大陆

  • T80179GrTx1；化合物 GrTx1GrTx1

    GrTx1, a peptide toxin derived from Grammostola rosea spider venom, selectively inhibits sodium channels Nav1.1, Nav1.2, Nav1.3, Nav1.4, Nav1.6, and Nav1.7, with IC50 values of 0.63 ?M, 0.23 ?M, 0.77 ?M, 1.29 ?M, 0.63 ?M, and 0.37 ?M, respectively [2]. This compound has applications in neurological disease research [1].

    价 格：￥电议型 号：T80179产 地：中国大陆

  • T80169ProTx-III；化合物 ProTx-IIIμ-TRTX-Tp1a；μ-TRTX-Tp1a

    ProTx-III, a spider venom peptide derived from the Peruvian green velvet tarantula, functions as a selective and potent inhibitor of the voltage-gated sodium channel Na v 1.7, exhibiting an IC 50 of 2.1 nM. Characterized by its inhibitor cystine knot motif (ICK), ProTx-III can attenuate the pain response and is applicable in research on chronic pain, epilepsy, and arrhythmia [1].

    价 格：￥电议型 号：T80169产 地：中国大陆

  • T80022(R)-tert-OMe-byakangelicin；化合物 (R)-tert-OMe-byakangelicin(R)-tert-OMe-byakangelicin

    (R)-tert-OMe-byakangelicin, a furanocoumarin, exhibits inhibitory effects on liver drug metabolizing enzyme (DME) activity and can be isolated from the immature fruits of Angelica sinensis [1] [2].

    价 格：￥电议型 号：T80022产 地：中国大陆

  • T79938Mortatarin G；化合物 Mortatarin GMortatarin G

    Mortatarin G (compound 3), a prenylated flavonoid derived from mulberry leaves, demonstrates potent α-glucosidase inhibition, evidenced by an IC50 value of 20.4±1.4 μM [1].

    价 格：￥电议型 号：T79938产 地：中国大陆

  • T79937Mortatarin F；化合物 Mortatarin FMortatarin F

    Mortatarin F (Compound 1), a renyleted flavonoid derived from mulberry leaves, functions as an α-glucosidase inhibitor with an IC50 value of 8.7 μM, making it pertinent for hypoglycemic research [1].

    价 格：￥电议型 号：T79937产 地：中国大陆

  • T79921Moloney murine leukemia virus RT；化合物 Moloney murine leukemia virus RTMoloney murine leukemia virus R

    Moloney murine leukemia virus reverse transcriptase (MMLV RT) is a monomeric replicative polymerase intrinsic to the retrovirus life cycle [1].

    价 格：￥电议型 号：T79921产 地：中国大陆

  • T79903Sirtuin-1 inhibitor 1；Sirtuin-1 抑制剂1Sirtuin-1 inhibitor 1

    Sirtuin-1 inhibitor 1 is an inhibitor against deacetylase-1 (Sirtuin-1) and can be used to study senescence and cell death in the organism.

    价 格：￥电议型 号：T79903产 地：中国大陆

  • T79868Tirfipiravir；化合物 TirfipiravirTirfipiravir

    Tirapiravir is an antiviral nucleoside analog that exhibits activity against both the novel coronavirus and influenza virus [1].

    价 格：￥电议型 号：T79868产 地：中国大陆

  • T79689SIRT6-IN-3；化合物 SIRT6-IN-3SIRT6-IN-3

    SIRT6-IN-3 (compound 8a), a selective SIRT6 inhibitor (IC50 = 7.49 μM), impedes the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and prompts apoptosis. It enhances the responsiveness of cancer cells to gemcitabine by obstructing the DNA damage repair pathway, thus serving as a valuable tool in pancreatic cancer research [1].

    价 格：￥电议型 号：T79689产 地：中国大陆

  • T79565Sirt1/2-IN-4；化合物 Sirt1/2-IN-4Sirt1/2-IN-4

    Sirt1/2-IN-4 (compound PS3) is a potent triple inhibitor of SIRT1, SIRT2, and SIRT3, exhibiting IC50 values of 1.2 μM (SIRT1), 1.9 μM (SIRT2), and 18.6 μM (SIRT3), respectively. It effectively inhibits p53 deacetylation, indicating potential anticancer properties [1].

    价 格：￥电议型 号：T79565产 地：中国大陆

  • T79564Sirt1/2-IN-3；化合物 Sirt1/2-IN-3Sirt1/2-IN-3

    Sirt1/2-IN-3 (compound PS9) serves as a dual inhibitor of SIRT1/2, exhibiting IC50 values of 1.4 μM (SIRT1) and 2.0 μM (SIRT2), respectively. This compound effectively inhibits p53 deacetylation while simultaneously elevating p53 and α-tubulin acetylation levels. Additionally, Sirt1/2-IN-3 promotes apoptosis and exhibits antiproliferative effects on human leukemia cell lines [1].

    价 格：￥电议型 号：T79564产 地：中国大陆

  • T79563Sirt1/2-IN-2；化合物 Sirt1/2-IN-2Sirt1/2-IN-2

    Sirt1/2-IN-2 (compound hsa55) serves as a dual inhibitor for SIRT1 with an IC50 of 1.8 μM and SIRT2 with an IC50 of 2.4 μM, respectively. It effectively inhibits p53 deacetylation while enhancing the acetylation of p53 and α-tubulin. The compound also promotes apoptosis and exhibits anti-proliferative effects on human leukemia cell lines [1].

    价 格：￥电议型 号：T79563产 地：中国大陆

  • T7929L-Aspartic Acid 4-Benzyl Ester；L-天冬氨酸-4-苄酯L-Aspartic Acid 4-Benzyl Ester

    L-Aspartic Acid 4-Benzyl Ester is a chelating agent that forms stable complexes with metal ions. It has been used to study the effect of metal ions on enzyme activity and to investigate the role of metal ions in the regulation of gene expression.

    价 格：￥电议型 号：T7929产 地：中国大陆

  • T79267Antihypertensive agent 3；化合物 Antihypertensive agent 3Antihypertensive agent 3

    Antihypertensive agent 3 (compound 4a), an angiotensin II receptor 1 antagonist, demonstrates antihypertensive activity in spontaneously hypertensive rats (SHRs) [1].

    价 格：￥电议型 号：T79267产 地：中国大陆

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