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  • T63440Dyrk1A-IN-2;化合物 Dyrk1A-IN-2Dyrk1A-IN-2

    Dyrk1A-IN-2 is a DYRK1A inhibitor (EC50: 37 nM). dyrk1A-IN-2 exhibits efficient promotion of human β-cell replication, as well as low cytotoxicity.

    价 格:¥电议型 号:T63440产 地:中国大陆

  • T63429SMO-IN-2;SMO抑制剂2SMO-IN-2

    SMO-IN-2 is a potent smoothened (SMO) inhibitor of hedgehog (Hh) signaling.SMO-IN-2 shows antiproliferative activity and anticancer activity against human medulloblastoma cell lines.SMO-IN-2 can be used in the study of cancer.

    价 格:¥电议型 号:T63429产 地:中国大陆

  • T63408mGAT3/4-IN-2;化合物 mGAT3/4-IN-2mGAT3/4-IN-2

    mGAT3/4-IN-2 are potent inhibitors of mGAT3/mGAT4 with their pIC50 values of 5.44 and 5.25, respectively.

    价 格:¥电议型 号:T63408产 地:中国大陆

  • T63385SARS-CoV-2 3CLpro-IN-2;化合物 SARS-CoV-2 3CLpro-IN-2SARS-CoV-2 3CLpro-IN-2

    SARS-CoV-2 3CLpro-IN-2 is a potent inhibitor of the 3CL protease pair and has shown research potential for SARS-CoV-2 disease.

    价 格:¥电议型 号:T63385产 地:中国大陆

  • T63370FtsZ-IN-2;化合物 FtsZ-IN-2FtsZ-IN-2

    FtsZ-IN-2 is an inhibitor of the bacterial cytokinin FtsZ and has an inhibitory effect on GTPase activity. ftsZ-IN-2 exhibited anti-staphylococcal effects with MIC values of 2 μg/ml for both MSSA and MRSA.

    价 格:¥电议型 号:T63370产 地:中国大陆

  • T63368CDK7-IN-2;化合物 CDK7-IN-2CDK7-IN-2

    CDK7-IN-2 is a potent inhibitor of CDK7. CDK7 is involved in transcription initiation using phosphorylation of the Rbpl subunit of RNA polymerase II (RNAPII), which is associated with temporal control of cell cycle and transcriptional activity.CDK7 has research potential for cancer diseases, especially aggressive and difficult-to-treat cancers.

    价 格:¥电议型 号:T63368产 地:中国大陆

  • T63357EGFR/HER2/CDK9-IN-2;化合物 EGFR/HER2/CDK9-IN-2EGFR/HER2/CDK9-IN-2

    EGFR/HER2/CDK9-IN-2 are potent inhibitors of EGFR/HER2/CDK9, and they exhibited significant antitumor effects with IC50s of 145.35, 129.07 and 117.13 nM, respectively.

    价 格:¥电议型 号:T63357产 地:中国大陆

  • T63348COX-2-IN-23;化合物 COX-2-IN-23COX-2-IN-23

    COX-2-IN-23 is a selective inhibitor of COX-2, with IC50 values of 0.28 and 20.14 μM for COX-2 and COX-1, respectively.COX-2-IN-23 exhibits anti-inflammatory effects as well as low ulcerogenic effects.

    价 格:¥电议型 号:T63348产 地:中国大陆

  • T63343ULK1-IN-2;ULK1抑制剂2ULK1-IN-2

    ULK1-IN-2 is a potent ULK1 inhibitor with potential anticancer activity, inducing apoptosis while blocking autophagy.ULK1-IN-2 has high cytotoxicity against cancer cells, with an IC50 value of 1.94 μM against A549 cells.ULK1-IN-2 can be used for the study of non-small-cell lung cancer.

    价 格:¥电议型 号:T63343产 地:中国大陆

  • T63341ALDH1A1-IN-2;ALDH1A1抑制剂2ALDH1A1-IN-2

    ALDH1A1-IN-2 is a potent aldehyde dehydrogenase 1a1 (aldh1a1) inhibitor with anticancer activity.ALDH1A1-IN-2 may be used in the study of breast cancer, inflammation or obesity.

    价 格:¥电议型 号:T63341产 地:中国大陆

  • T63336COX-2-IN-29;化合物 COX-2-IN-29COX-2-IN-29

    COX-2-IN-29 is a selective inhibitor of orally active COX-2 (IC50: 0.005 μM).

    价 格:¥电议型 号:T63336产 地:中国大陆

  • T63329PD-1/PD-L1-IN-25;化合物 PD-1/PD-L1-IN-25PD-1/PD-L1-IN-25

    PD-1/PD-L1-IN-25 is an inhibitor of PD-1/PD-L1 interaction (IC50: 16.17 nM) that effectively activates anti-tumor immunity of T cells in PBMCs. PD-1/PD-L1-IN-25 can be used to study cancer.

    价 格:¥电议型 号:T63329产 地:中国大陆

  • T6330Linperlisib;化合物PI3Kδ-IN-2PI3Kδ-IN-2;PI3Kδ-IN-2

    Linperlisib (PI3Kδ-IN-2) is a potent and selective inhibitor of PI3Kδ

    价 格:¥电议型 号:T6330产 地:中国大陆

  • T63292SARS-CoV-2-IN-24;化合物 SARS-CoV-2-IN-24SARS-CoV-2-IN-24

    SARS-CoV-2-IN-24 is a potent inhibitor of papain-like proteases (PLpro) that induces conformational changes in SARS-COV-2 papain-like proteases, inhibits SARS-COV-2 replication, and can be used to study SARS-CoV-2.

    价 格:¥电议型 号:T63292产 地:中国大陆

  • T63288SCP1-IN-2;化合物 SCP1-IN-2SCP1-IN-2

    SCP1-IN-2 is a potent, selective, and metric inhibitor of SCP1. SCP1-IN-2 is able to induce REST degradation and inhibit its transcriptional activity. High levels of REST protein induce tumor growth in some glioblastoma cells. sCP1-IN-2 has the potential to perform studies of glioblastomas in which REST transcriptional activity drives growth.

    价 格:¥电议型 号:T63288产 地:中国大陆

  • T63274FLT3/ITD-IN-2;化合物 FLT3/ITD-IN-2FLT3/ITD-IN-2

    FLT3/ITD-IN-2 is a potent inhibitor of FLT3-ITD and is able to act on FLT3D835Y (IC50: 0.3 nM), FLT3 (IC50: 0.4 nM) and FLT3-ITD (IC50: 1.0 nM).FLT3/ITD-IN-2 effectively inhibits the phosphorylation of FLT3 and is able to effectively inhibit the proliferation of acute myeloid leukemia cells.

    价 格:¥电议型 号:T63274产 地:中国大陆

  • T63270HPK1-IN-29;化合物 HPK1-IN-29HPK1-IN-29

    HPK1-IN-29 is a potent inhibitor of HPK1, in which hematopoietic progenitor kinase 1 (HPK1) is a negative regulator of the activation response of dendritic cells (DCs), T cells and B cells. HPK1-IN-29 is able to enhance anti-tumor immunity in humans and shows potential for the study of immune-related diseases, especially tumors.

    价 格:¥电议型 号:T63270产 地:中国大陆

  • T63250β-Glucuronidase-IN-2;化合物 β-Glucuronidase-IN-2β-Glucuronidase-IN-2

    β-Glucuronidase-IN-2 is a potent inhibitor of E. coli β-glucuronidase β-glucuronidase (IC50: 0.24 μM, Ki: 1.09 μM) and exhibits anti-proliferative effects with potential for anti-cancer and anti-inflammatory therapeutic studies.

    价 格:¥电议型 号:T63250产 地:中国大陆

  • T63243GRP78-IN-2;化合物 GRP78-IN-2GRP78-IN-2

    GRP78-IN-2 is a glucose regulatory protein 78 (GRP78) inhibitor that preferentially targets GRP78 on the cell surface and has significant anti-angiogenic and anti-cancer effects without affecting other normal cells.

    价 格:¥电议型 号:T63243产 地:中国大陆

  • T63223hTrkA-IN-2;化合物 hTrkA-IN-2hTrkA-IN-2

    hTrkA-IN-2 is a selective hTrkA metamorphosis inhibitor (IC50: 3.9 nM).

    价 格:¥电议型 号:T63223产 地:中国大陆

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