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  • T62904PknB-IN-2；化合物 PknB-IN-2PknB-IN-2

    PknB-IN-2 (Compound 10) is an inhibitor of Mycobacterium tuberculosis protein kinase B (PknB) (IC50: 12.1 μM).

    价 格：￥电议型 号：T62904产 地：中国大陆

  • T62901VEGFR-2-IN-27；化合物 VEGFR-2-IN-27VEGFR-2-IN-27

    VEGFR-2-IN-27 (compound 7a) is a potent inhibitor of VEGFR-2 (IC50: 14.8 nM) and can be used in anticancer studies.

    价 格：￥电议型 号：T62901产 地：中国大陆

  • T62849iNOS-IN-2；化合物 iNOS-IN-2iNOS-IN-2

    iNOS-IN-2 (Compound 53) is a potent inducible nitric oxide synthase (iNOS) protein down-regulator. iNOS-IN-2 effectively inhibits NO production (IC50: 6.4 μM). iNOS-IN-2 can be used in studies of chronic inflammation.

    价 格：￥电议型 号：T62849产 地：中国大陆

  • T62834SARS-CoV-2-IN-22；化合物 SARS-CoV-2-IN-22SARS-CoV-2-IN-22

    SARS-CoV-2-IN-22 is a SARS-CoV-2 pseudovirus inhibitor (IC50: 16.96 μM).

    价 格：￥电议型 号：T62834产 地：中国大陆

  • T62819SARS-CoV-2 nsp14-IN-2；化合物 SARS-CoV-2 nsp14-IN-2SARS-CoV-2 nsp14-IN-2

    SARS-CoV-2 nsp14-IN-2 is a potent inhibitor of SARS-CoV-2 Nsp14 methyltransferase (IC50: 0.093 μM). SARS-CoV-2 nsp14-IN-2 has the potential to be used in COVID-19 studies.

    价 格：￥电议型 号：T62819产 地：中国大陆

  • T62799HDAC-IN-28；化合物 HDAC-IN-28HDAC-IN-28

    HDAC-IN-28 is a novel inhibitor of HDAC that significantly inhibits tumour growth and metastasis.

    价 格：￥电议型 号：T62799产 地：中国大陆

  • T62776EGFR/HER2-IN-2；化合物 EGFR/HER2-IN-2EGFR/HER2-IN-2

    EGFR/HER2-IN-2 (Compound ZINC35560729) is a dual EGFR and HER2 inhibitor that acts on both EGFR (IC50: 5.02 μM) and HER2 (IC50: 0.83 μM).

    价 格：￥电议型 号：T62776产 地：中国大陆

  • T62755HCAIX-IN-2；化合物 HCAIX-IN-2HCAIX-IN-2

    HCAIX-IN-2 (compound 9d) is a selective inhibitor of carbonic anhydrase and acts on hCA IX (Ki: 24.6 nM) and hCA XII (Ki: 45.3 nM).

    价 格：￥电议型 号：T62755产 地：中国大陆

  • T62728AChE-IN-24；化合物 AChE-IN-24AChE-IN-24

    AChE-IN-24 is a potent inhibitor of AChE that crosses the blood-brain barrier. hAChE is strongly inhibited by AChE-IN-24 (IC50: 0.053 μM). aChE-IN-24 can be used to study Alzheimer´s disease (AD).

    价 格：￥电议型 号：T62728产 地：中国大陆

  • T62717A2AAR/HDAC-IN-2；化合物 A2AAR/HDAC-IN-2A2AAR/HDAC-IN-2

    A2AAR/HDAC-IN-2 is a potent dual A2AAR/HDAC inhibitor.A2AAR/HDAC-IN-2 shows good affinity for A2AAR (Ki:10.3 nM) and inhibits HDAC1 well (IC50:18.5 nM). A2AAR/HDAC-IN-2 can be used in anti-tumour studies.

    价 格：￥电议型 号：T62717产 地：中国大陆

  • T62704HBV-IN-23；化合物 HBV-IN-23HBV-IN-23

    HBV-IN-23 (Compound 5k) is an inhibitor of HBV DNA replication (IC50: 0.58 μM). HBV-IN-23 inhibits drug-sensitive and drug-resistant strains. HBV-IN-23 induces apoptosis in HepG2 cells and exhibits anti-hepatocellular carcinoma (HCC) effects.

    价 格：￥电议型 号：T62704产 地：中国大陆

  • T62703NTPDase-IN-2；化合物 NTPDase-IN-2NTPDase-IN-2

    NTPDase-IN-2 (compound 5g) selectively inhibits NTPDase-2 and NTPDase-8 with IC50 values of 0.04 ?M and 2.27 ?M, respectively, and exhibits non-competitive inhibition towards h-NTPDase-1 and h-NTPDase-2, with a Km of 74 ?M for h-NTPDase-2. This compound is applicable in researching cancer, immunological disorders, and bacterial infections [1].

    价 格：￥电议型 号：T62703产 地：中国大陆

  • T62693Tubulin polymerization-IN-29；化合物 Tubulin polymerization-IN-29Tubulin polymerization-IN-29

    Tubulin polymerization-IN-29 is a potent inhibitor of microtubule protein polymerization and shows potent anti-proliferative effects.Tubulin polymerization-IN-29 induces cell cycle arrest in HeLa cells at G2/M phase.

    价 格：￥电议型 号：T62693产 地：中国大陆

  • T62685IMP2-IN-2；化合物 IMP2-IN-2IMP2-IN-2

    IMP2-IN-2 is a potent and selective inhibitor of IMP2 with IC50 values of 120.9 μM and 236.7 μM for the inhibition of IMP2 interaction with RNA_A and RNA_B, respectively. IMP2-IN-2 can be used in cancer research.

    价 格：￥电议型 号：T62685产 地：中国大陆

  • T62674LSD1-IN-21；化合物 LSD1-IN-21LSD1-IN-21

    LSD1-IN-21 is a potent, blood-brain barrier permeable LSD1 (lysine specific demethylase-1) inhibitor (IC50: 0.956 μM).LSD1-IN-21 significantly reduces the pro-inflammatory cytokine TNF-α and exhibits good anti-cancer and anti-inflammatory effects.

    价 格：￥电议型 号：T62674产 地：中国大陆

  • T62664Glucosylceramide synthase-IN-2；化合物 Glucosylceramide synthase-IN-2Glucosylceramide synthase-IN-2

    Glucosylceramide synthase-IN-2 (compound T-690) is a potent, blood-brain barrier-permeable, orally active inhibitor of glucosylceramide synthase (GCS) that acts on human GCS (IC50: 15 nM) and mouse GCS (IC50: 190 nM). Glucosylceramide synthase-IN-2 is capable of non-competitive inhibition of C8 ceramide and UDP glucose.

    价 格：￥电议型 号：T62664产 地：中国大陆

  • T62653FGFR-IN-2；化合物 FGFR-IN-2FGFR-IN-2

    FGFR-IN-2 (compound 1) is a potent inhibitor of FGFR, acting on FGFR1 (IC50: 7.3 nM), FGFR2 (IC50: 4.3 nM), FGFR3 (IC50: 7.6 nM) and FGFR4 (IC50: 11 nM).

    价 格：￥电议型 号：T62653产 地：中国大陆

  • T62632HPK1-IN-21；化合物 HPK1-IN-21HPK1-IN-21

    HPK1-IN-21 is a potent, orally active HPK1 kinase inhibitor with a Ki value of 0.8 nM.

    价 格：￥电议型 号：T62632产 地：中国大陆

  • T62621pan-HER-IN-2；化合物 pan-HER-IN-2pan-HER-IN-2

    pan-HER-IN-2 (Compound C6) is an orally active, reversible, broad-spectrum HER inhibitor that acts on EGFR (IC50: 0.72 nM), HER4 (IC50: 2.0 nM), EGFRT790M (IC50: 8.2 nM), and L858R (IC50: 75.1 nM). pan-HER-IN-2 induces apoptosis and has anti-tumour effects.

    价 格：￥电议型 号：T62621产 地：中国大陆

  • T62614ALK5-IN-29；化合物 ALK5-IN-29ALK5-IN-29

    ALK5-IN-29 is a selective inhibitor of activin receptor-like kinase (ALK).ALK5-IN-29 inhibits activin receptor-like kinase activity (IC50 ≤ 10 nM).AALK5-IN-29 inhibits tumour growth and can be used in the study of proliferative diseases such as cancer.

    价 格：￥电议型 号：T62614产 地：中国大陆

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