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T62150Cap-dependent endonuclease-IN-25；化合物 Cap-dependent endonuclease-IN-25Cap-dependent endonuclease-IN-2
Cap-dependent endonuclease-IN-25 is a macrocyclic pyridoxal derivative and a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN). The Cap-dependent endonuclease IN-25 has potential for the study of viral infections caused by viruses of the Orthomyxoviridae family.
价 格：￥电议型 号：T62150产 地：中国大陆
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T62135Tubulin polymerization-IN-25；化合物 Tubulin polymerization-IN-25Tubulin polymerization-IN-25
Tubulin polymerization-IN-25 is a selective, dual tubulin polymerization (IC50: 1.11 μM) and farnesyl transferase (FTase) (IC50: 0.39 μM) inhibitor. polymerization-IN-25 exhibits cytotoxicity against cancer cells and blocks cell proliferation.
价 格：￥电议型 号：T62135产 地：中国大陆
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T62115HBV-IN-24；化合物 HBV-IN-24HBV-IN-24
HBV-IN-24 (compound (2 S, 6S)-1a) is a potent inhibitor of HBV. HBV-IN-24 is a strong inhibitor of HBV DNA (EC50: 0.6 nM), HBsAg (EC50: 0.6 nM) and HBeAg (EC50: 4.6 nM). antiviral effect and was able to improve neurotoxicity.
价 格：￥电议型 号：T62115产 地：中国大陆
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T62101hCAXII-IN-2；化合物 hCAXII-IN-2hCAXII-IN-2
hCAXII-IN-2 (compound 5i) is a potent inhibitor of human carbonic anhydrase XII (hCA XII) (Ki: 84.2 nM) and hCA IX (Ki: 268.5 nM), with low activity against hCA I and hCA II.
价 格：￥电议型 号：T62101产 地：中国大陆
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T62088TRPC5-IN-2；化合物 TRPC5-IN-2TRPC5-IN-2
TRPC5-IN-2 is a potent inhibitor of TRPC5.
价 格：￥电议型 号：T62088产 地：中国大陆
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T62064PDE4B/7A-IN-2；化合物 PDE4B/7A-IN-2PDE4B/7A-IN-2
This compound is a dual 5-HT1A/5-HT7 receptor antagonist (5-HT1A Ki = 8 nM, Kb = 0.04 nM; 5-HT7 Ki = 451 nM, Kb = 460 nM) with additional inhibitory activity against PDE4B/PDE7A (PDE4B IC50 = 80.4 μM; PDE7A IC50 = 151.3 μM). Its antidepressant-like effect surpasses that of the reference agent, escitalopram.
价 格：￥电议型 号：T62064产 地：中国大陆
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T62021TrxR-IN-2；化合物 TrxR-IN-2TrxR-IN-2
TrxR-IN-2 is a potential thioredoxin reductase (TrxR) inhibitor. TrxR-IN-2 has research value in the chemotherapy of drug-resistant hepatocellular carcinoma.
价 格：￥电议型 号：T62021产 地：中国大陆
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T62011LDN-209929 dihydrochloride；化合物 LDN-209929 dihydrochlorideLDN-209929 dihydrochloride
LDN-209929 dihydrochloride is a potent and selective inhibitor of haspin kinase (IC50= 55 nM). LDN-209929 dihydrochloride shows180-fold selectivity verses DYRK2 (IC50= 9.9 μM).
价 格：￥电议型 号：T62011产 地：中国大陆
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T61986PRMT5-IN-21；化合物 PRMT5-IN-21PRMT5-IN-21
PRMT5-IN-21 (compound 1) is a potent inhibitor of cyclonucleoside PRMT5.
价 格：￥电议型 号：T61986产 地：中国大陆
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T61982Human carbonic anhydrase II-IN-2；化合物 Human carbonic anhydrase II-IN-2Human carbonic anhydrase II-IN-
Human carbonic anhydrase II-IN-24 (Compound R-13) is a potent human carbonic anhydrase (hCA) inhibitor. Human carbonic anhydrase II-IN-24 shows K i s of 60.7, 320.7, 2298, and 35.2 nM for hCA I, II, IV and IX, respectively.
价 格：￥电议型 号：T61982产 地：中国大陆
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T61978ACC1/2-IN-2；化合物 ACC1/2-IN-2ACC1/2-IN-2
ACC1/2-IN-2 (compound PF-3) is a potent inhibitor of ACC1/2 with IC50s of 22 and 48 nM for ACC1 and ACC2, respectively. ACC1/2-IN-2 shows antiproliferation activity and has research value in cancer research.
价 格：￥电议型 号：T61978产 地：中国大陆
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T61974CAII-IN-2；化合物 CAII-IN-2CAII-IN-2
CAII-IN-2 (compound 3g) is a thiosemicarbazide derivative. CAII-IN-2 is a potent, selective carbonic anhydrase-II (CA-II) inhibitor with an IC50 of 12.1 μM for bovine CA-II. CAII-IN-2 has research value in carbonic anhydrase related biological disorders.
价 格：￥电议型 号：T61974产 地：中国大陆
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T61966PI3K-IN-26；化合物 PI3K-IN-26PI3K-IN-26
PI3K-IN-26 is an effective PI3K inhibitor. PI3K-IN-26 inhibits the proliferation of SU-DHL-6 cells, IC50= 36 nM.
价 格：￥电议型 号：T61966产 地：中国大陆
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T61961Pyruvate Carboxylase-IN-2；化合物 Pyruvate Carboxylase-IN-2Pyruvate Carboxylase-IN-2
Pyruvate Carboxylase-IN-2 is a natural analog of erianin. Pyruvate Carboxylase-IN-2 (compound 29) is a potent inhibitor of pyruvate carboxylase (PC). In cell lysate-based and cell-based PC activity assays, Pyruvate Carboxylase-IN-2 shows IC 50 s of 0.065 and 0.097 μM, respectively. Pyruvate Carboxylase-IN-2 mediates the anticancer effect in human hepatocellular carcinoma (HCC).
价 格：￥电议型 号：T61961产 地：中国大陆
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T61954HDAC-IN-29；化合物 HDAC-IN-29HDAC-IN-29
HDAC-IN-29 (compound 13b) is a potent pan- HDAC inhibitor with antitumor activity.
价 格：￥电议型 号：T61954产 地：中国大陆
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T61953Zika virus-IN-2；化合物 Zika virus-IN-2Zika virus-IN-2
Zika virus-IN-2 (Compd 3) is a Zika virus inhibitor (EC 50= 7.4 μM).
价 格：￥电议型 号：T61953产 地：中国大陆
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T61948MraY-IN-2；化合物 MraY-IN-2MraY-IN-2
MraY-IN-2 (compound 6) is an effective inhibitor of bacterial transposase MraY (IC50=4.5 μ M), and can be used for antibacterial research.
价 格：￥电议型 号：T61948产 地：中国大陆
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T61932Nesuparib；化合物NesuparibJPI-547/OCN-201；JPI-547/OCN-201
Nesuparib (JPI-547/OCN-201) is a potent PARP inhibitor with inhibitory effects on PARP and TNKS1.Nesuparib has antitumor activity and can be used in the treatment of tumors, endocrine and metabolic disorders, genitourinary disorders, and can be used in the study of neuropathic pain, neurodegenerative disorders, and cardiovascular diseases.
价 格：￥电议型 号：T61932产 地：中国大陆
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T61927hDDAH-1-IN-2 sulfate；化合物 hDDAH-1-IN-2 sulfatehDDAH-1-IN-2 sulfate
hDDAH-1-IN-2 is a selective, orally active inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) with an excellent profile regarding cell toxicity/viability.
价 格：￥电议型 号：T61927产 地：中国大陆
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T61910COX-2/5-LOX-IN-2；化合物 COX-2/5-LOX-IN-2COX-2/5-LOX-IN-2
COX-2/5-LOX-IN-2 is a benzothiophen-2-ylpyrazole carboxylic acid derivative. COX-2/5-LOX-IN-2 (5b) inhibited both COX-2 and 5-LOX. The IC50s of COX-2/5-LOX-IN-2 inhibiting COX-1, COX-2 and 5-LOX were 5.40, 0.01 and 1.78 μM, respectively. COX-2/5-LOX-IN-2 showed more analgesic and anti-inflammatory activities than Celecoxib and Indomethacin.
价 格：￥电议型 号：T61910产 地：中国大陆
