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上海陶术生物科技有限公司 主营产品：生物试剂,实验服务等

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  • T61591SARS-CoV-2-IN-20；化合物 SARS-CoV-2-IN-20SARS-CoV-2-IN-20

    SARS-CoV-2-IN-20 (Compound 1a) is a highly effective inhibitor of SARS-CoV-2, displaying an impressive EC50 value of 6.5 μM. With its exceptional inhibitory properties, SARS-CoV-2-IN-20 holds great potential for advancing research on infectious diseases [1].

    价 格：￥电议型 号：T61591产 地：中国大陆

  • T61586TGFβ-IN-2；化合物 TGFβ-IN-2TGFβ-IN-2

    TGFβ-IN-2 (Compound 9d) effectively inhibits the accumulation of total collagen induced by TGF-β in NRK-49F cells, with an IC 50 value of 4.31 μM. It also suppresses the in vitro protein expression of COL1A1, α-SMA, and p-Smad3, which are induced by TGF-β. Additionally, TGFβ-IN-2 shows promise as a potential anti-fibrosis compound for in vivo applications through oral administration [1].

    价 格：￥电议型 号：T61586产 地：中国大陆

  • T61581LasR-IN-2；化合物 LasR-IN-2LasR-IN-2

    LasR-IN-2, a compound that inhibits the activity of LasR, forms hydrogen bonding with the TRY-56 residue. It finds application in the study of bacterial infection, neutropenia, severe burns, and chronic lung disease in cystic fibrosis (CF) [1].

    价 格：￥电议型 号：T61581产 地：中国大陆

  • T61570Mt KARI-IN-2；化合物 Mt KARI-IN-2Mt KARI-IN-2

    Mt KARI-IN-2 (compound 5b) is a highly effective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), with a Ki value of 2.02 μM. This compound also exhibits inhibitory activity against Mtb H37Rv, with a MIC value of 0.78 μM. Moreover, Mt KARI-IN-2 demonstrates low cytotoxicity, as evidenced by a HEK IC 50 greater than 86 μg/mL [1].

    价 格：￥电议型 号：T61570产 地：中国大陆

  • T61563HSV-1/HSV-2-IN-2；化合物 HSV-1/HSV-2-IN-2HSV-1/HSV-2-IN-2

    HSV-1/HSV-2-IN-2 is a compound that acts as an inhibitor of HSV-1, HSV-2, and VV, demonstrating antiviral activity with EC50 values of 6.8, 8.9, and 8.9 μM, respectively [1].

    价 格：￥电议型 号：T61563产 地：中国大陆

  • T61558HBV-IN-21；化合物 HBV-IN-21HBV-IN-21

    HBV-IN-21 (Compound II-8b) is a potent inhibitor of HBV DNA replication, exhibiting an IC50 of 2.2 μM. It demonstrates a favorable binding affinity (K D = 60.0 μM) for the HBV 4 capsid protein, thereby enabling effective interaction [1].

    价 格：￥电议型 号：T61558产 地：中国大陆

  • T61556GRK6-IN-2；GRK6抑制剂2GRK6-IN-2

    GRK6-IN-2 is a potent G protein-coupled receptor kinase 6 (GRK6) inhibitor with potential antitumor activity.GRK6-IN-2 has been studied in multiple myeloma.

    价 格：￥电议型 号：T61556产 地：中国大陆

  • T61553ATPase-IN-2；化合物 ATPase-IN-2ATPase-IN-2

    ATPase-IN-2 is a compound that acts as an inhibitor of ATPase, with an IC50 value of 0.9 μM. It also inhibits the glycohydrolase activity of C. difficile toxin B (TcdB) with an AC50 value of 30.91 μM. ATPase-IN-2 is commonly utilized in ATP-related research [1].

    价 格：￥电议型 号：T61553产 地：中国大陆

  • T61551Trk-IN-20；化合物 Trk-IN-20Trk-IN-20

    Trk-IN-20 is a 3-vinylindazole derivative compound that effectively inhibits the functions of Trk kinases. It accomplishes this by suppressing the phosphorylation of TrkA, TrkB, and TrkC, with IC50 values of 1.6 nM, 2.9 nM, and 2.0 nM, respectively [1].

    价 格：￥电议型 号：T61551产 地：中国大陆

  • T61549HDAC8-IN-2；化合物 HDAC8-IN-2HDAC8-IN-2

    HDAC8-IN-2 (compound 5o) is a potent HDAC8 inhibitor, with IC50 values of 0.27 μM and 0.32 μM for smHDAC8 (Schistosoma mansoni histone deacetylase 8) and hHDAC8, respectively. It effectively kills schistosome larvae and greatly reduces egg laying in adult worm pairs [1].

    价 格：￥电议型 号：T61549产 地：中国大陆

  • T61547ATG7-IN-2；化合物 ATG7-IN-2ATG7-IN-2

    ATG7-IN-2 (compound 1) is a highly potent inhibitor of the ATG7 protein, displaying an IC 50 value of 0.089 μM. This compound effectively suppresses the activity of autophagy marker LC3B, thereby regulating the autophagy process [1].

    价 格：￥电议型 号：T61547产 地：中国大陆

  • T61494JAK-IN-21；JAK抑制剂21JAK-IN-21

    JAK-IN-21 is a selective and potent JAK inhibitor that inhibits JAK1, JAK2, J2V617F and TYK2 with IC50 values of 1.73, 2.04, 109 and 62.9 nM, respectively.

    价 格：￥电议型 号：T61494产 地：中国大陆

  • T61473FGFR2-IN-2；化合物 FGFR2-IN-2FGFR2-IN-2

    FGFR2-IN-2 is a selective FGFR2 inhibitor with an IC 50 of 29 nM.

    价 格：￥电议型 号：T61473产 地：中国大陆

  • T61458HIF-PHD-IN-2；化合物 HIF-PHD-IN-2HIF-PHD-IN-2

    HIF-PHD-IN-2 (compound 25) is a highly effective PHD inhibitor, displaying IC50 values below 100 nM for PHD1, PHD2, and PHD3 [1].

    价 格：￥电议型 号：T61458产 地：中国大陆

  • T61437HPK1-IN-26；化合物 HPK1-IN-26HPK1-IN-26

    HPK1-IN-26, a novel compound, is a potent inhibitor of both HPK1 and GLK. This small molecule exhibits promise in aiding the study of animal pathogen infection [1].

    价 格：￥电议型 号：T61437产 地：中国大陆

  • T61426NOS-IN-2；化合物 NOS-IN-2NOS-IN-2

    NOS-IN-2 (Compound 4i), an imidamide-derived NOS inhibitor, exhibits high potency and selectivity, specifically inhibiting iNOS with an IC50 of 20 μM while sparing eNOS. Demonstrating minimal toxicity, it is suitable for research on inflammatory disorders [1].

    价 格：￥电议型 号：T61426产 地：中国大陆

  • T61408BChE-IN-2；化合物 BChE-IN-2BChE-IN-2

    BChE-IN-2 (compound 22) is a highly effective inhibitor of BChE, exhibiting a Ki value of 0.099 μM. This compound represents a promising pyrimidine and pyridine derivative for investigating Alzheimer´s disease (AD). [1]

    价 格：￥电议型 号：T61408产 地：中国大陆

  • T61353PqsR-IN-2；化合物 PqsR-IN-2PqsR-IN-2

    PqsR-IN-2 (Compound 19) is a highly potent inhibitor of PqsR, the transcriptional regulator responsible for quorum sensing in Pseudomonas aeruginosa. It effectively suppresses pyocyanin production without causing significant cytotoxicity, making it a promising compound for therapeutic applications [1].

    价 格：￥电议型 号：T61353产 地：中国大陆

  • T61349HIF-1α-IN-2；HIF-1α 抑制剂2HIF-1α-IN-2

    HIF-1α-IN-2 is a novel and highly potent HIF-1α inhibitor with anticancer and antitumor activity that inhibits the expression of HIF-1α and VEGF in a dose-dependent manner and inhibits cell migration.

    价 格：￥电议型 号：T61349产 地：中国大陆

  • T61331α-Glucosidase-IN-20；化合物 α-Glucosidase-IN-20α-Glucosidase-IN-20

    α-Glucosidase-IN-20 (Compound 3B) is a highly effective and orally active inhibitor of α-glucosidase. It exhibits potent anti-diabetic properties, as evidenced by its IC50 value of 3.01 μM [1].

    价 格：￥电议型 号：T61331产 地：中国大陆

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