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  • T61015hCAIX/XII-IN-2；化合物 hCAIX/XII-IN-2hCAIX/XII-IN-2

    hCAIX/XII-IN-2 (compound 6a) is a potent and selective inhibitor of hCAIX and hCAXII. The Ki values of hCAIX/XII-IN-2 for hCAI, hCAII, hCAIX and hCAXII are >10000, >10000, 30.0, 3.6 nM, respectively [1].

    价 格：￥电议型 号：T61015产 地：中国大陆

  • T60995LDHA/PDKs-IN-2；化合物 LDHA/PDKs-IN-2LDHA/PDKs-IN-2

    LDHA/PDKs-IN-2 (compound 20k) is a potent LDHA and PDKs dual inhibitor with IC50 values of 0.7 and 1.6 μM, respectively. LDHA/PDKs-IN-2 increases oxygen consumption as well as decreases the lactate formation. LDHA/PDKs-IN-2 shows the potential for the cancer research which reduces the proliferation of A549 cell with an EC 50 of 15.7 μM [1].

    价 格：￥电议型 号：T60995产 地：中国大陆

  • T60973HPK1-IN-24；化合物 HPK1-IN-24HPK1-IN-24

    HPK1-IN-24 (example 51) has potential to be used in the cancer research which is an inhibitor of hematopoietic progenitor kinase 1 (HPK1) (Ki = 100 nM) [1].

    价 格：￥电议型 号：T60973产 地：中国大陆

  • T60967Atg4B-IN-2；Atg4B抑制剂2Atg4B-IN-2

    Atg4B-IN-2 is a potent and selective Atg4B inhibitor with anticancer activity that inhibits the activity of Atg4B and PLA2.Atg4B-IN-2 resists the anticancer activity of anti-desiccation-resistant prostate cancer drugs through autophagy.

    价 格：￥电议型 号：T60967产 地：中国大陆

  • T60949Complex III-IN-2；化合物 Complex III-IN-2Complex III-IN-2

    Complex III-IN-2 (Compd 4d-2) is an inhibitor of complex III that has antifungal activity with an EC 50 of 29.31 mg/L and 29.98 mg/L against R. solani and sclerotinia sclerotiorum, respectively [1].

    价 格：￥电议型 号：T60949产 地：中国大陆

  • T60936Tubulin polymerization-IN-24；化合物 Tubulin polymerization-IN-24Tubulin polymerization-IN-24

    Tubulin polymerization-IN-24 (compound HMBA) is a potent inhibitor of tubulin polymerization that increase the GTP hydrolysis rate and inhibits microtubule assembly. Tubulin polymerization-IN-24 induces apoptosis and cell cycle arrest in G2/M phase. Tubulin polymerization-IN-24 inhibits proliferation of MCF-7 cells [1].

    价 格：￥电议型 号：T60936产 地：中国大陆

  • T60908SARM1-IN-2；SARM1抑制剂2SARM1-IN-2

    SARM1-IN-2 is a potent SARM1 inhibitor for the study of metabolic and neurological related diseases.

    价 格：￥电议型 号：T60908产 地：中国大陆

  • T60904ERCC1-XPF-IN-2；化合物ERCC1-XPF-IN-2ERCC1-XPF-IN-2

    ERCC1-XPF-IN-2 is active in nucleotide excision repair, cisplatin enhancement and γH2AX assays. ERCC1-XPF-IN-2 is a potent inhibitor of ERCC1-XPF endonuclease with an IC 50 value of 0.6 μM [1].

    价 格：￥电议型 号：T60904产 地：中国大陆

  • T60850MIF-IN-2；MIF 抑制剂2MIF-IN-2

    MIF-IN-2 is a heterocyclic macrophage migration inhibitory factor (MIF) inhibitor with anticancer activity for the study of cancer and autoimmune disorders.CAS ??13460-73-86-5

    价 格：￥电议型 号：T60850产 地：中国大陆

  • T60841SARS-CoV-2-IN-23；化合物 SARS-CoV-2-IN-23SARS-CoV-2-IN-23

    SARS-CoV-2-IN-23 (compound GRL-0617) is an inhibitor of SARS-COV-2 papain-like protease (PLpro) (IC 50 = 2.3 μM) [1].

    价 格：￥电议型 号：T60841产 地：中国大陆

  • T60837AChE/BuChE-IN-2；化合物 AChE/BuChE-IN-2AChE/BuChE-IN-2

    AChE/BuChE-IN-2 (Compound 5f) can cross the BBB that is an orally active inhibitor of AChE and BuChE with IC 50 values of 0.72 μM and 0.16 μM, respectively. AChE/BuChE-IN-2 shows potent inhibition of self-induced β-amyloid (Aβ) aggregation with an IC 50 of 62.52 μM and a non-competitive inhibition with AChE [1].

    价 格：￥电议型 号：T60837产 地：中国大陆

  • T60833Mycobactin-IN-2；化合物 Mycobactin-IN-2Mycobactin-IN-2

    Mycobactin-IN-2 (compound 49) is an inhibitor of mycobactin biosynthesis that binds to salicyl-AMP ligase (MbtA). MbtA is a key enzyme of mycobactin biosynthetic pathway [1].

    价 格：￥电议型 号：T60833产 地：中国大陆

  • T60828AAK1-IN-2；化合物 AAK1-IN-2AAK1-IN-2

    AAK1-IN-2 (compound (S)-31) can be used in neuropathic pain research that is a potent, selective and brain-penetrant Adaptor Protein 2-Associated Kinase 1(AAK1) inhibitor (IC 50 = 5.8 nM) [1].

    价 格：￥电议型 号：T60828产 地：中国大陆

  • T60810Influenza virus-IN-2；化合物 Influenza virus-IN-2Influenza virus-IN-2

    Influenza virus-IN-2 (compound 19) has anti-influenza A virus activities that is a potent inhibitor of influenza virus with an CC 50 of 150.85 μM and EC 50 of 2.58 μM. Influenza virus-IN-2 concentration-dependently inhibits the PAN endonuclease with EC 50 of 489.39 nM [1].

    价 格：￥电议型 号：T60810产 地：中国大陆

  • T60802Tubulin polymerization-IN-2；化合物 Tubulin polymerization-IN-2Tubulin polymerization-IN-2

    Tubulin Polymerization-IN-2 is a powerful anticancer agent that targets β-tubulin, exhibiting an IC 50 of 0.92 μM. It demonstrates promising efficacy against a range of cancer cell lines including leukemia, non-small cell lung, renal, prostate, and breast cancers [1].

    价 格：￥电议型 号：T60802产 地：中国大陆

  • T60769COX-2/PI3K-IN-2；化合物 COX-2/PI3K-IN-2COX-2/PI3K-IN-2

    COX-2/PI3K-IN-2 (compound 5f) has properties of anti-inflammatory and anti-cancer. COX-2/PI3K-IN-2 is a selective inhibitor of COX-2 (Ki = 3.02 nM) as well as a potent inhibitor of PI3K (IC 50 = 2.78 nM) [1].

    价 格：￥电议型 号：T60769产 地：中国大陆

  • T60760HDAC10-IN-2；化合物 HDAC10-IN-2HDAC10-IN-2

    HDAC10-IN-2 (compound 10c) regulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells. HDAC10-IN-2 is a potent and highly selective inhibitor of HDAC10 (IC50 = 20 nM) [1].

    价 格：￥电议型 号：T60760产 地：中国大陆

  • T60749Autophagy-IN-2；化合物 Autophagy-IN-2Autophagy-IN-2

    Autophagy-IN-2 (Compound 7h) is an inhibitor of autophagic flux which induces cancer cell apoptosis and can be used for the research of triple-negative breast cancer [1].

    价 格：￥电议型 号：T60749产 地：中国大陆

  • T60735Tubulin polymerization-IN-22；化合物 Tubulin polymerization-IN-22Tubulin polymerization-IN-22

    Tubulin polymerization-IN-22 arrests cell cycle at G2/M phase as well as induces apoptosis. Tubulin polymerization-IN-22 is an inhibitor of tubulin polymerization (IC 50 = 8.1 μM) [1].

    价 格：￥电议型 号：T60735产 地：中国大陆

  • T60714gp120-IN-2；化合物 gp120-IN-2gp120-IN-2

    gp120-IN-2 (compound 4i) exhibits anti-HIV-1 activity which is a potent inhibitor of HIV-1 gp120 with an IC 50 of 7.5 μM and CC 50 of 112.93 μM. gp120-IN-2 dose-dependently shows cytotoxicity in SUP-T1 cells [1].

    价 格：￥电议型 号：T60714产 地：中国大陆

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