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T19206β-Lactamase-IN-1；化合物β-Lactamase-IN-14-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one
β-Lactamase-IN-1 (4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one) is a β-Lactamase inhibitor and targets the infection of Neisseria gonorrhoeae.
价 格：￥电议型 号：T19206产 地：中国大陆
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T1873Tenovin-3；化合物Tenovin-3Tenovin3；Tenovin3
Tenovin-3 acts as a p53 activator.
价 格：￥电议型 号：T1873产 地：中国大陆
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T18722MAC glucuronide α-hydroxy lactone-linked SN-38；化合物 T18722MAC glucuronide α-hydroxy lactone-linked SN
MAC glucuronide α-hydroxy lactone-linked SN-38 (Topoisomerase I inhibitor) is a cytotoxic drug linker that maintains a stabilized lactone form, showing efficacy against L540cy and Ramos cells, with IC50 values of 99 and 105 ng/mL, respectively[1].
价 格：￥电议型 号：T18722产 地：中国大陆
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T18538MAC glucuronide phenol-linked SN-38；化合物 T18538MAC glucuronide phenol-linked SN-38
MAC glucuronide phenol-linked SN-38, a pH-sensitive lactone and DNA topoisomerase I inhibitor drug linker, exhibits cytotoxicity in L540cy and Ramos cells, with IC50 values of 113 ng/mL and 67 ng/mL, respectively[1].
价 格：￥电议型 号：T18538产 地：中国大陆
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T18473N3-PEG3-vc-PAB-MMAE；化合物 T18473N3PEG3vcPABMMAE|||N3-PEG3-vc-PAB-MMAE|||N-3-PEG3-vc-PAB-MMAE|||N3 PEG3
N3-PEG3-vc-PAB-MMAE, a drug-linker conjugate designed for Antibody-Drug Conjugates (ADC), features the integration of monomethyl auristatin E (MMAE), a tubulin inhibitor, via a 3-unit polyethylene glycol (PEG) linker. This compound demonstrates significant antitumor activity.
价 格：￥电议型 号：T18473产 地：中国大陆
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T17731LCL2A-SN-38 DCA 1279680-68-0(free base)；化合物CL2A-SN-38 DCACL2A-SN-38 DCA 1279680-68-0(free base)
CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC).. CL2A-SN-38 is composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A is a noncleavable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable t
价 格：￥电议型 号：T17731L产 地：中国大陆
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T17731CL2A-SN-38；化合物CL2A-SN-38CL2A|||CL2A SN 38|||bystander effect|||SN-38|||antitumor|||CL2A-SN-38|||Inhi
CL2A-SN-38 is a drug-linker conjugate consisting of SN-38, a potent DNA topoisomerase I inhibitor, and linker CL2A, for the manufacture of antibody drug conjugates (ADCs). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A is a nonclaevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulf
价 格：￥电议型 号：T17731产 地：中国大陆
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T17338(4-Oxo-4H-quinazolin-3-yl)-acetic acid；化合物 T17338(4-Oxo-4H-quinazolin-3-yl)-acetic acid
(4-Oxo-4H-quinazolin-3-yl)-acetic acid is an alkyl chain-derived PROTAC linker suitable for the synthesis of PROTACs[1].
价 格：￥电议型 号：T17338产 地：中国大陆
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T173334-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol；化合物 T173334-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol
4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol is an alkyl chain-derived PROTAC linker employed for the synthesis of PROTACs[1].
价 格：￥电议型 号：T17333产 地：中国大陆
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T1703SN-38；伊立替康杂质BNK012|||SN 38；7-乙基-10-羟基喜树碱|||NK012|||伊立替康杂质B|||SN 38
SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, which inhibits DNA and RNA synthesis (IC50=0.077/1.3 μM). SN-38 has antitumor activity and induces autophagy.
价 格：￥电议型 号：T1703产 地：中国大陆
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T16660N3-PEG3-CH2COOH；化合物 T16660N-3-PEG3-CH2COOH|||N3 PEG3 CH2COOH|||PROTAC Linker 14|||N3-PEG3-CH2COOH|||
N3-PEG3-CH2COOH (PROTAC Linker 14) is a PEG-based compound utilized for the synthesis of PROTACs.
价 格：￥电议型 号：T16660产 地：中国大陆
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T16130Mps1-IN-3；化合物Mps1-IN-3Mps1-IN-3
Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).
价 格：￥电议型 号：T16130产 地：中国大陆
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T16124MMP13-IN-3；化合物MMP13-IN-3MMP13-IN-3
MMP13-IN-3 is >1000 selective over other MMPs. MMP13-IN-3 is an effective, selective, and orally active MMP-13 inhibitor (IC50=1 nM) for the potential treatment of osteoarthritis.
价 格：￥电议型 号：T16124产 地：中国大陆
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T16029Mcl1-IN-3；化合物 T16029Mcl1-IN-3
Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively.
价 格：￥电议型 号：T16029产 地：中国大陆
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T15278Fezolinetant；化合物FezolinetantESN-364；ESN-364
Fezolinetant (ESN-364) is an antagonist of the neurokinin 3 receptor (NK3R). It is used for the treatment of menopausal hot flushes.
价 格：￥电议型 号：T15278产 地：中国大陆
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T15043D5D-IN-326化合物 T15043D-5D-IN-326|||D5D IN 326|||D5DIN326
D5D-IN-326 is an orally active delta-5 desaturase (D5D) inhibitor (IC50s: 72 and 22 nM for rat and human D5D in enzymic and cell-based assays). It has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistance and decreases body weight in diet-induced obese C57BL/6J mice.
价 格：￥电议型 号：T15043产 地：中国大陆
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T14990CDK12-IN-3；化合物 T14990CDK12-IN-3
CDK12-IN-3 is a selective CDK12 inhibitor (IC50: 491 nM in an enzymatic assay).
价 格：￥电议型 号：T14990产 地：中国大陆
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T1439Lacidipine拉西地平SN-305|||拉西地平|||GX-1048|||GR-43659X
Lacidipine (SN-305) is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia. It displays specificity in the vascular smooth muscle, where it acts as an antihypertensive agent to dilate peripheral arterioles and reduce blood pressure.
价 格：￥电议型 号：T1439产 地：中国大陆
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T140373α-Aminocholestane；3α-氨基胆甾烷5α-Cholestan-3α-amine；5α-Cholestan-3α-amine
3α-Aminocholestane (5α-Cholestan-3α-amine) is a potent inhibitor of inositol-5´-phosphatase 1 (SHIP1) containing the SH2 structural domain (IC50 : 2.5 μM) for research and immune-related diseases.
价 格：￥电议型 号：T14037产 地：中国大陆
