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T11737K-Ras G12C-IN-3；化合物 T11737K-Ras G12C-IN-3
Heterocyclic compounds as covalent inhibitors of G12C mutant K-Ras protein useful for treating cancers.K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C.
价 格：￥电议型 号：T11737产 地：中国大陆
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T11704JAK-IN-3；化合物 T11704JAK-IN-3
JAK-IN-3 is a potent JAK inhibitor, with IC50 values of 3 nM, 5 nM, 34 nM and 70 nM for JAK3, JAK1, TYK2 and JAK2, respectively.
价 格：￥电议型 号：T11704产 地：中国大陆
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T11682Isofistularin-3；化合物 T11682Isofistularin-3
Isofistularin-3, a direct DNA-competitive DNMT1 inhibitor with an IC50 of 13.5 μM, functions as a DNA demethylating agent, leading to cell cycle arrest and increased sensitivity to TRAIL in cancer cells. Additionally, it can be employed as an ADC cytotoxin.
价 格：￥电议型 号：T11682产 地：中国大陆
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T11617IDO-IN-3；化合物 T11617IDO-IN-3
IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 290 nM).
价 格：￥电议型 号：T11617产 地：中国大陆
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T11579HSL-IN-3；化合物HSL-IN-3HSL inhibitor 3|||Ethyl 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzoate；HSL inh
HSL-IN-3 (HSL inhibitor 3) is a boronic acid derivative that is an inhibitor of hormone-sensitive lipase(HSL).
价 格：￥电议型 号：T11579产 地：中国大陆
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T11562HIF-2α-IN-3；HIF-2α 抑制剂 3HIF-2α-IN-3
HIF-2α-IN-3 is a HIF-2α alteration inhibitor with anti-tumor properties and may be used in the study of cardiovascular disease.
价 格：￥电议型 号：T11562产 地：中国大陆
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T11557FASN-IN-3；化合物FASN-IN-3FASN-IN-3
FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).
价 格：￥电议型 号：T11557产 地：中国大陆
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T11541HCV-IN-30；化合物HCV-IN-30u00A0HCV-IN-30
HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).
价 格：￥电议型 号：T11541产 地：中国大陆
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T11540HCV-IN-3；化合物 T11540HCV-IN-3
HCV-IN-3 is a hepatitis C virus (HCV) NS3/4a protein inhibitor (IC50: 20 μM; Kd: 29 μM).
价 格：￥电议型 号：T11540产 地：中国大陆
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T11298FLT3-IN-3；化合物FLT3-IN-3FLT3-IN-3
FLT3-IN-3 is an effective FLT3 inhibitor, and the IC50s of FLT3 WT and FLT3 D835Y are 13 and 8 nM, respectively.
价 格：￥电议型 号：T11298产 地：中国大陆
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T11112DUB-IN-3；化合物DUB-IN-3DUB-IN-3
DUB-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor and the IC50 for USP8 is 0.56 μM.
价 格：￥电议型 号：T11112产 地：中国大陆
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T11026DHODH-IN-3；化合物 T11026DHODH-IN-3
DHODH-IN-3 is an effective inhibitor of human dihydroorotate dehydrogenase (HsDHODH) with IC50 value of 261 nM. DHODH-IN-3 binds to the ubiquinone binding cavity in DHODH with a Kiapp of 32 nM. DHODH-IN-3 has the potential to treat malaria.
价 格：￥电议型 号：T11026产 地：中国大陆
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T11025hDHODH-IN-3；化合物hDHODH-IN-3DHODH-IN-2；DHODH-IN-2
hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.
价 格：￥电议型 号：T11025产 地：中国大陆
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T10832CL2-SN-38；化合物 T10832CL-2-SN-38|||CL2-SN-38|||CL2SN38|||CL2 SN 38；CL-2-SN-38|||CL2-SN-38|||CL2SN38|||
CL2-SN-38, a part of the antibody-drug conjugate (ADC), can conjugate with the anti-Trop-2-humanized antibody hRS7. SN-38 is an inhibitor of DNA topoisomerase I.
价 格：￥电议型 号：T10832产 地：中国大陆
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T10791CHK1-IN-3；化合物CHK1-IN-3CHK1-IN-3
CHK1-IN-3 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 0.4 nM).
价 格：￥电议型 号：T10791产 地：中国大陆
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T10771CETP-IN-3；化合物 T10771CETP-IN-3
CETP-IN-3 is an inhibitor of the plasma glycoprotein cholesterol ester transfer protein (CETP), elevating HDL-C through inhibition of CETP.
价 格：￥电议型 号：T10771产 地：中国大陆
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T10737CDK4/6-IN-3；化合物 T10737CDK4/6-IN-3
CDK4/6-IN-3 is a brain-penetrant CDK4/CDK6 inhibitor (Kis: <0.3 nM and 2.2 nM) used for the treatment of glioblastoma. It inhibits CDK1 with a Ki of 110 nM.
价 格：￥电议型 号：T10737产 地：中国大陆
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T10725Cdc7-IN-3；化合物 T10725Cdc7-IN-3
Cdc7-IN-3 is a potent inhibitor of Cdc7 kinase.
价 格：￥电议型 号：T10725产 地：中国大陆
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T10722CD80-IN-3；化合物CD80-IN-3CD80-IN-3
CD80-IN-3 is a potent CD80 inhibitor and inhibits CD80/CD28 interaction (Kd: 125 nM; EC50: 630 nM).
价 格：￥电议型 号：T10722产 地：中国大陆
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T10651c-Kit-IN-3；化合物c-Kit-IN-3c-Kit-IN-3
c-Kit-IN-3 is a selective inhibitor of c-KIT kinase with IC50s of 4 nM and 8 nM for c-Kit (wt) and c-Kit (T670I).
价 格：￥电议型 号：T10651产 地：中国大陆
