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T39693Polyketide synthase 13-IN-3;Polyketide synthase 13-IN-3Polyketide synthase 13-IN-3
Polyketide synthase 13-IN-3 (compound 41) is a potent inhibitor of polyketide synthase 13, demonstrating a minimum inhibitory concentration (MIC) range of 0.0625-0.125 μg/mL against the M. tuberculosis strain H37Rv.
价 格:¥电议型 号:T39693产 地:中国大陆
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T39683Human β-defensin-3;Human β-defensin-3Human β-defensin-3|||HβD-3;Human β-defensin-3|||HβD-3
Human β-defensin-3 (HβD-3) is an antibiotic antimicrobial peptide synthesized by epithelial cells. It exhibits potent antimicrobial properties and mitigates inflammatory cytokine responses. HβD-3 efficiently targets various microorganisms, displaying IC90 values ranging from 6 to 25 μg/ml.
价 格:¥电议型 号:T39683产 地:中国大陆
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T39567HDAC1/2-IN-3HDAC1/2-IN-3HDAC1/2-IN-3
HDAC1/2-IN-3 is an inhibitor of both HDAC1 and HDAC2, demonstrating IC50 values of 0-5 nM and 5-10 nM, respectively.
价 格:¥电议型 号:T39567产 地:中国大陆
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T39514Keap1-Nrf2-IN-3Keap1-Nrf2-IN-3Keap1-Nrf2-IN-3
Keap1-Nrf2-IN-3 is a KEAP1:NRF2 protein protein interaction inhibitor, and with a K d value of 2.5 nM for KEAP1 protein.
价 格:¥电议型 号:T39514产 地:中国大陆
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T39453ERK-IN-3 benzenesulfonate;ERK-IN-3 benzenesulfonateERK-IN-3 benzenesulfonate
ERK-IN-3 benzenesulfonate is a potent and orally active inhibitor of ERK . ERK-IN-3 benzenesulfonate inhibits ERK1/2 with low single-digit nM IC 50 values. ERK-IN-3 benzenesulfonate can be used for the research of cancers driven by RAS mutations.
价 格:¥电议型 号:T39453产 地:中国大陆
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T39200β-catenin-IN-37;β-catenin-IN-37β-catenin-IN-37
β-Catenin-IN-37 is a selective inhibitor of the protein-protein interaction between β-Catenin and T-cell factor (Tcf), known as β-catenin/Tcf PPI. It effectively inhibits canonical Wnt signaling and impedes the growth of colorectal cancer cells SW480 and HCT116, with IC50 values of 20 μM and 31 μM, respectively.
价 格:¥电议型 号:T39200产 地:中国大陆
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T38914MPO-IN-3;MPO-IN-3MPO-IN-3
MPO-IN-3, a powerful inhibitor of myeloperoxidase (MPO), is described as such in example 191 of WO2013068875A1. MPO, a heme-containing enzyme, is classified under the peroxidase superfamily.
价 格:¥电议型 号:T38914产 地:中国大陆
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T38683SCD1 inhibitor-3;化合物SCD1 inhibitor-3SCD1-IN-3|||SCD1 inhibitor-3|||SCD1 inhibitor 17a;SCD1-IN-3|||SC
SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety. SCD1 inhibitor-3 demonstrates strong potential for research in metabolic diseases, including obesity, type II diabetes, and dyslipidemia, as well as various skin conditions like acne and cancer.
价 格:¥电议型 号:T38683产 地:中国大陆
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T3844217,17-(Ethylenedioxy)androst-4-en-3-one;17,17-(Ethylenedioxy)androst-4-en-3-one17,17-(Ethylenedioxy)
17,17-(Ethylenedioxy)androst-4-en-3-one (4- androstene- 3, 17- dione- 17- cyclic ethylene ketal) is an effective ingredient in cosmetics, which can be used for acne and promote hair growth research. 17,17-(Ethylenedioxy)androst-4-en-3-one can inhibit the reductase activity and inhibit the bond of a receptor protein and 5α-DHT.
价 格:¥电议型 号:T38442产 地:中国大陆
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T38175MPro N3MPro N3MPro N3|||MPro N-3
Coronavirus main protease (Mpro) inhibitor (respective IC50 values are 2.7, 4 and 8.8 μM for MHV-A29, HCoV-229E and FOPV replication in vitro). Inhibits viral cell infection in an MHV plaque reduction assay. Also inhibits SARS-CoV-2 viral cell entry in a plaque reduction assay (IC50 = 16.8 μM).
价 格:¥电议型 号:T38175产 地:中国大陆
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T38154N-3-hydroxydecanoyl-L-Homoserine lactone;N-3-hydroxydecanoyl-L-Homoserine lactoneN-3-hydroxydecanoyl
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Different quorum sensing molecules are produced at different times in bacterial population growth and have distinct cellular effects mediated through changes in gene expression. N-3-hydroxydecanoyl-L-Homoserine lactone is a small diffusible signaling molecule secreted by various bacteria. This lactone is produced via lactonolysis from 3-oxodecanoyl-homoserine lactone, al
价 格:¥电议型 号:T38154产 地:中国大陆
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T3807(-)-Gallocatechin gallate;没食子儿茶素没食子酸酯(-)-gallocatechin-3-O-gallate|||(-)-Gallocatechol gallate|||Gal
(-)-Gallocatechin gallate ((-)-gallocatechin-3-O-gallate) is the polyphenol isolated from tea, with cancer-preventive activities. (-)-Gallocatechin gallate decreases osteoclastogenesis at 20 microM.
价 格:¥电议型 号:T3807产 地:中国大陆
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T38006LOX-IN-3;LOX-IN-3LOX-IN-3
LOX-IN-3, an orally active inhibitor of lysyl oxidase (LOX), holds potential application in the fields of fibrosis, cancer, and angiogenesis research[1].
价 格:¥电议型 号:T38006产 地:中国大陆
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T3799Isorhamnetin-3-O-neohespeidoside;异鼠李素-3-O-新橙皮苷Isorhamnetin 3-O-neohesperidin|||Isorhamnetin 3-O-neoh
Isorhamnetin-3-O-neohespeidoside (Calendoflavoside) is a flavonol glycoside extract used as an anti-oxidant.
价 格:¥电议型 号:T3799产 地:中国大陆
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T37630Tetrahydrothiophen-3-one;四氢噻吩-3-酮Tetrahydrothiophen-3-one
Tetrahydrothiophen-3-one can be used as food spices.
价 格:¥电议型 号:T37630产 地:中国大陆
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T37385Glutaminase-IN-3;谷氨酰胺酶抑制剂3Glutaminase-IN-3
Glutaminase-IN-3 is a potent Glutaminase 1 inhibitor with potential antitumor activity and inhibits GLS1 for cancer research.
价 格:¥电议型 号:T37385产 地:中国大陆
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T37339N-3-oxo-tetradecanoyl-L-Homoserine lactone;N-3-oxo-tetradecanoyl-L-Homoserine lactone3-oxo-C14-HSL||
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by the synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-3-oxo-tetradecanoyl-L-homoserine lactone (3-oxo-C14-HSL) is
价 格:¥电议型 号:T37339产 地:中国大陆
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T37338N-3-oxo-pentanoyl-L-Homoserine lactone;N-3-oxo-pentanoyl-L-Homoserine lactoneN-3-oxo-pentanoyl-L-Hom
N-3-oxo-pentanoyl-L-Homoserine lactone is a chain-shortened derivative of the bacterial quorum sensing signaling molecule N-3-oxo-octanoyl-L-homoserine lactone .1It inhibits binding of the autoinducer N-3-oxo-hexanoyl homoserine lactone toE. colicontaining the transcription factor LuxR when used at a concentration of 230 nM.2It acts as an autoinducer to activate theV. fischeriluminescence system inE. coliwhen used at concentrations ranging from 20 to 200 nM.
价 格:¥电议型 号:T37338产 地:中国大陆
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T37337N-3-oxo-hexadecanoyl-L-Homoserine lactone;N-3-oxo-hexadecanoyl-L-Homoserine lactoneN-3-oxo-hexadecan
N-3-oxo-hexadecanoyl-L-Homoserine lactone is an unusual, substituted, long-chain N-acyl-homoserine lactone (AHL) produced by some bacteria, including strains of Agrobacterium vitis and Pseudomonas. Like other AHLs, this C16-containing form is thought to be involved in quorum sensing. Substituted, long-chain AHLs, including N-3-oxo-tetradecanoyl-L-homoserine lactone , prime for systemic acquired resistance to pathogen attack in plants.
价 格:¥电议型 号:T37337产 地:中国大陆
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T37336N-3-oxo-hexadec-11(Z)-enoyl-L-Homoserine lactone;N-3-oxo-hexadec-11(Z)-enoyl-L-Homoserine lactoneN-3
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gener
价 格:¥电议型 号:T37336产 地:中国大陆