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T11250Ezetimibe-d4;化合物 T11250SCH 58235 D4;SCH 58235 D4
Ezetimibe D4, a deuterium-labeled variant of Ezetimibe, functions as an inhibitor of Niemann-Pick C1-like1 (NPC1L1) and is recognized for its potent activation of Nrf2.
价 格:¥电议型 号:T11250产 地:中国大陆
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T1125Shikonin;紫草素NSC 252844|||Isoarnebin 4|||(+)-Shikonin|||Alkanna Red|||C.I. 75535|||Anchusa acid;NSC 2
Shikonin (Anchusa acid) is a natural product, a TMEM16A chloride channel inhibitor (IC50=6.5 μM) and selective PKM2 inhibitor. Shikonin exhibits antitumor, anti-inflammatory and wound healing activities.
价 格:¥电议型 号:T1125产 地:中国大陆
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T11249LDxd;化合物DxdExatecan derivative for ADC|||OQM5SD32BQ|||UNII-OQM5SD32BQ;Exatecan derivative for ADC|||O
Dxd (OQM5SD32BQ) is a potent inhibitor of DNA topoisomerase I with an IC50 of 0.31 μM. It is used as a conjugated drug of HER2-targeting ADC.
价 格:¥电议型 号:T11249L产 地:中国大陆
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T11249Exatecan;依喜替康DX-8951|||DX-8951f;依喜替康|||DX-8951|||DX-8951f
Exatecan (DX-8951f) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL).Exatecan has antitumor activity and may be used in cancer research.
价 格:¥电议型 号:T11249产 地:中国大陆
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T11248Evogliptin tartrate;化合物 T11248DA-1229 tartrate;DA-1229 tartrate
Evogliptin tartrate has potential for anti-atherosclerosis therapy that targets arterial inflammation. Evogliptin tartrate is a potent, orally bioavailable and selective dipeptidyl peptidase-4 (DPP-4) inhibitor, with antidiabetic activity.
价 格:¥电议型 号:T11248产 地:中国大陆
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T11247Etravirine D4;依曲韦林 D4R-165335 D4|||TMC-125 D4;R-165335 D4|||TMC-125 D4|||依曲韦林 D4
Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. Etravirine D4 is the deuterium labeled Etravirine.
价 格:¥电议型 号:T11247产 地:中国大陆
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T11246Etoricoxib-d4;依托考昔 D4MK-0663 D4|||L-791456 D4|||Etoricoxib D4;MK-0663 D4|||依托考昔 D4|||L-791456 D4|||E
Etoricoxib D4 is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood.Etoricoxib D4 is a deuterium labeled Etoricoxib.
价 格:¥电议型 号:T11246产 地:中国大陆
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T11244Etimizol;化合物EtimizolEthymisol|||Ethimizole|||Ethymisole;Ethymisol|||Ethimizole|||Ethymisole
Etimizol (Ethimizole)?was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain). The positive effect of Etimizol on memory is related to its influence on the consolidation stage.
价 格:¥电议型 号:T11244产 地:中国大陆
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T11243Ethyl tosylcarbamate;化合物 T11243Ethyl tosylcarbamate
Gliclazide is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Ethyl tosylcarbamate is an intermediate in the synthesis of Gliclazide (G409877).
价 格:¥电议型 号:T11243产 地:中国大陆
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T11242Ethyl glucuronide;化合物 T11242Ethyl glucuronide
Ethyl glucuronide is an endogenous metabolite.
价 格:¥电议型 号:T11242产 地:中国大陆
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T11241p38 MAPK-IN-2;化合物 T11241p38 MAPK-IN-2
p38 MAPK-IN-2 is an inhibitor of p38 kinase.
价 格:¥电议型 号:T11241产 地:中国大陆
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T11240Ethacrynic acid D5;化合物 T11240Ethacrynic acid D5
Ethacrynic acid, a diuretic, functions as an inhibitor of L-type voltage-dependent and store-operated calcium channels, facilitating the relaxation of airway smooth muscle (ASM) cells. It exhibits anti-inflammatory effects, notably reducing retinoid-induced ear edema in mice, and inhibits glutathione S-transferases (GSTs), making it a potent suppressor of the NF-kB signaling pathway. Additionally, ethacrynic acid modulates leukotriene formation. A variant, Ethacrynic acid D5, is distinguished by
价 格:¥电议型 号:T11240产 地:中国大陆
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T1124Flumethasone氟米松氟米松|||Flumetasone|||RS-2177|||NSC-54702
Flumethasone (RS-2177) is a glucocorticoid receptor agonist, with anti-inflammatory, antipruritic and vasoconstrictive properties.
价 格:¥电议型 号:T1124产 地:中国大陆
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T11239Ethacizine hydrochloride;乙沙西嗪盐酸盐NIK-244|||Ethacizin|||NIK-244 hydrochloride;NIK-244|||Ethacizin|||NI
Ethacizine hydrochloride (NIK-244) has antiarrhythmic activity, and its effects are related to cardiac activity and can be used to study arrhythmias and myocardial infarction.
价 格:¥电议型 号:T11239产 地:中国大陆
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T11238LEtamicastat hydrochloride;依他米司特盐酸盐BIA 5-453 hydrochloride;BIA 5-453 hydrochloride
Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension.
价 格:¥电议型 号:T11238L产 地:中国大陆
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T11238Etamicastat;化合物 T11238BIA 5-453;BIA 5-453
Etamicastat can be used in the research of cardiovascular diseases. Etamicastat (BIA 5-453) is a potent and reversible dopamine-β-hydroxylase (DBH) inhibitor with an IC50 value of 107 nM.
价 格:¥电议型 号:T11238产 地:中国大陆
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T11237LCamizestrant TFA;Camizestrant三氟乙酸盐Camizestrant TFA(2222844-89-3 Free base)|||AZD-9833 TFA;Camizestra
Camizestrant TFA (AZD-9833 TFA) is a potent and orally active antagonist of estrogen receptor (ER).
价 格:¥电议型 号:T11237L产 地:中国大陆
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T11237Camizestrant;化合物CamizestrantEstrogen receptor antagonist 2;Estrogen receptor antagonist 2
Camizestrant (Estrogen receptor antagonist 2) is an antagonist of the estrogen receptor and can be used in studies about ER+ HER2-advanced breast cancer[1].
价 格:¥电议型 号:T11237产 地:中国大陆
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T11236Giredestrant tartrate;Giredestrant酒石酸盐Estrogen receptor antagonist 1;Estrogen receptor antagonist 1
Giredestrant tartrate (Estrogen receptor antagonist 1) is a novel, orally active, selective and effective non-steroidal estrogen receptor antagonist. Giredestrant tartrate strongly binds to ER, resulting in the failure of ER to activate the transcription of targeted genes and promoting the degradation of ER protein. Giredestrant tartrate can be used to treat tumor diseases.
价 格:¥电议型 号:T11236产 地:中国大陆
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T11235Estradiol 3-sulfamate;雌二醇 3-氨基磺酸E2MATE|||BLE 00084|||ES-J 995;E2MATE|||BLE 00084|||ES-J 995
Estradiol 3-sulfamate (BLE 00084) is an orally active and highly potent steroidal estrone sulfatase (ES) inhibitor.Estradiol 3-sulfamate has a K(i) value of 73 nM for ES in human placental microsomes and can be used in the study of breast cancer.
价 格:¥电议型 号:T11235产 地:中国大陆