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T3793015(R)-17-phenyl trinor Prostaglandin F2α；15(R)-17-phenyl trinor Prostaglandin F2α15(R)-17-phenyl tri
17-phenyl trinor Prostaglandin F2α N-ethyl amide (17-phenyl trinor PGF2α) is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name 17-phenyl trinor PGF2α ethyl amide. Investigations in our lab have shown that 17-phenyl trinor PGF2α ethyl amide is converted by an amidase enzymatic activity in the human cornea to yield the corresponding free acid, with a conversion rate of about 25 μg/cornea/24 hours. The free acid, 17-ph
价 格：￥电议型 号：T37930产 地：中国大陆
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T37919Prostaglandin F1α；Prostaglandin F1αPGF1α|||Prostaglandin F1α；PGF1α|||Prostaglandin F1α
Prostaglandin F1α (PGF1α) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1α and PGF2α have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10-11 M. [1] PGF1α binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF2α. [2] It is only half as active as PGF2α in inducing human respiratory smooth muscle contractions in vitro. [3]
价 格：￥电议型 号：T37919产 地：中国大陆
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T37918Prostaglandin E2 isopropyl ester；Prostaglandin E2 isopropyl esterProstaglandin E2 isopropyl ester；Pr
Prostaglandin E2 (PGE2) isopropyl ester is a more lipophilic form of the free acid, PGE2. PG esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid by endogenous esterases upon in vivo administration, making the esters useful prodrugs. In general, the C-1 esters of PGs show greatly diminished receptor activity in vitro compared to the parent free acids.
价 格：￥电议型 号：T37918产 地：中国大陆
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T3784020-hydroxy Prostaglandin F2α；20-hydroxy Prostaglandin F2α20-hydroxy Prostaglandin F2α；20-hydroxy Pro
20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing 20-hydroxy PGF2α and its 15-hydroxy PGDH metabolites. Cells from male rabbits exhibit only the 15-hydroxy PGDH pathway.
价 格：￥电议型 号：T37840产 地：中国大陆
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T3783920-hydroxy Prostaglandin E2；20-hydroxy Prostaglandin E220-hydroxy Prostaglandin E2；20-hydroxy Prosta
20-hydroxy Prostaglandin E2 (20-hydroxy PGE2) is a product of cytochrome P450 metabolism of PGE2 . ω-Oxidation at C-20 followed by β-oxidation and the loss of up to four carbons from the lower side chain is a prominent metabolic pathway for PGE2. 20-hydroxy PGE2 is the putative first intermediate in this chain of chemical transformations.
价 格：￥电议型 号：T37839产 地：中国大陆
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T3777819(R)-hydroxy Prostaglandin E1；19(R)-hydroxy Prostaglandin E119(R)-hydroxy Prostaglandin E1；19(R)-hy
19(R)-hydroxy Prostaglandin E1 is an agonist of EP1 and EP3 receptor subtypes and exhibits contractile activity on smooth muscle and is the major prostaglandin in primate semen.
价 格：￥电议型 号：T37778产 地：中国大陆
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T3777717-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide；17-trifluoromethylphenyl trinor Prosta
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor Prostaglandin F2α (17-trifluoromethylphenyl trinor PGF2α) is an analog of PGF2α that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoro
价 格：￥电议型 号：T37777产 地：中国大陆
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T37773tetranor-PGEM；tetranor-PGEMtetranor-Prostaglandin E Metabolite|||tetranor-PGEM；tetranor-Prostaglandi
tetranor-PGEM is the major urinary metabolite of PGE1 and PGE2, and is used as a marker of PGE2 biosynthesis.[1],[2] About 15% of an infused dose of PGE2 appears as this metabolite in the urine of humans. Normal healthy males excrete 7-40 μg of tetranor-PGEM over a 24-hour period.[1]
价 格：￥电议型 号：T37773产 地：中国大陆
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T37328Prostaglandin H1；Prostaglandin H1Prostaglandin H1；Prostaglandin H1
Prostaglandin H1 is the cyclooxygenase metabolite of DGLA, a CRTh2 agonist and a precursor of a family of 1 anti-inflammatory prostaglandins. Prostaglandin H1 can be used in the study of inflammation.
价 格：￥电议型 号：T37328产 地：中国大陆
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T37327Prostaglandin F2α 1,15-lactone；Prostaglandin F2α 1,15-lactoneProstaglandin F2α 1,15-lactone；Prostagl
PGF2α 1,15-lactone is a lipid-soluble internal ester of PGF2α. Hydrolysis of the lactone readily produces free PGF2α in plasma. In rhesus monkeys, a total dose of 15 mg of PGF2α 1,15-lactone terminates early pregnancy, whereas PGF2α is ineffective.
价 格：￥电议型 号：T37327产 地：中国大陆
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T37326Prostaglandin F2α 1,11-lactone；化合物T37326Prostaglandin F2α 1,11-lactone|||PGF2α 1,11-lactone；Prostagl
Prostaglandin F2α 1,11-lactone (PGF2α 1,11-lactone) is a lipid-soluble prodrug of Prostaglandin F2α and can be used in studies about treating glaucoma. Prostaglandin F2α 1,11-lactone is active as an antifertility agent with greatly reduced vasoactivity.
价 格：￥电议型 号：T37326产 地：中国大陆
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T372752,3-dinor-11β-Prostaglandin F2α；2,3-dinor-11β-Prostaglandin F2α2,3-dinor-11β-Prostaglandin F2α；2,3-d
2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where it represented approximately 1% and 4% of the infused radiolabeled dose, respectively. 2,3-dinor-11β-PGF2α has also been recovered from the urine of mastocytosis patients, where it is excreted in large amounts. In human asthmatic patients, 2,3-dinor-11β-PGF2α represents about 40% (as determined by GC/MS) of the immunoreactive 11β-PGF2α wh
价 格：￥电议型 号：T37275产 地：中国大陆
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T3726415(R)-15-methyl Prostaglandin D2；化合物 T3726415(R)15methyl PGD2；15(R)15methyl PGD2
15(R)-15-methyl Prostaglandin D2 (15(R)15methyl PGD2) is a synthetic analogue of PGD2 and a selective and potent CRTH2/DP2 receptor agonist that modulates eosinophil CD11b expression, actin polymerisation and chemotaxis.
价 格：￥电议型 号：T37264产 地：中国大陆
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T3725713,14-dihydro-15-keto Prostaglandin D1；13,14-dihydro-15-keto Prostaglandin D113,14-dihydro-15-keto P
Prostaglandin D1 (PGD1) is the theoretical D-series metabolite of dihomo-γ-linolenic acid (DGLA), but to date it has not been isolated as a natural product. It is an inhibitor of ADP-induced platelet aggregation in humans with an IC50 value of 320 ng/ml, about 1/10 as potent as PGD2. 13,14-dihydro-15-keto Prostaglandin D1 (13,14-dihydro-15-keto PGD1) is the theoretical metabolite of PGD1 via the 15-hydroxy PG dehydrogenase metabolic pathway. No biological studies for this compound have been repo
价 格：￥电议型 号：T37257产 地：中国大陆
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T371658-iso Prostaglandin F2β；8-iso Prostaglandin F2β8-iso Prostaglandin F2β；8-iso Prostaglandin F2β
8-iso Prostaglandin F2β can be used in related research in the field of life sciences. Its product number is T37165 and CAS number is 177020-26-7.
价 格：￥电议型 号：T37165产 地：中国大陆
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T36908Bimatoprost grenod；化合物 Bimatoprost grenod15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2α；1
Bimatoprost grenod(15-(6-nitroxyhexanoyl)-17-phenyl trinor PGF2α) is a nitric oxide-donating derivative of 17-phenyl trinor PGF2α.1It increases cGMP levels in rabbit aqueous humor and iris ciliary body when topically administered at a concentration of 0.042%. Topical administration of 15-(6-nitroxylhexanoyl)-17-phenyl trinor PGF2α(0.14%) reduces intraocular hypertension (IOP) in a rabbit model of hypertonic saline-induced transient ocular pressure. It also reduces IOP in a cynomolgus monkey mode
价 格：￥电议型 号：T36908产 地：中国大陆
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T368299-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2；9-deoxy-9-methylene-16,16-dimethyl Prostaglandin
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 with an extended half-life in vivo. In combination with various other prostaglandin derivatives, it results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of meteneprost and 7.5 mg of 17-phenyl trinor PGF1α is very effective in terminating early pregnancy. This prostaglandin mixture is ineffective on monkeys in their third trimes
价 格：￥电议型 号：T36829产 地：中国大陆
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T3677513,14-dihydro Prostaglandin E1；13,14-dihydro Prostaglandin E113,14-dihydro Prostaglandin E1；13,14-di
13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound. It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM, respectively. 13,14-dihydro PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 which has an IC50 value of 40 nM. Also, 13,14-dihydro PGE1 was shown to activate adenylate cyclase in NCB-20 hyb
价 格：￥电议型 号：T36775产 地：中国大陆
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T3677211-deoxy Prostaglandin F1β；11-deoxy Prostaglandin F1β11-deoxy Prostaglandin F1β；11-deoxy Prostagland
11-deoxy PGF1β is a synthetic analog of PGF1β. In contrast to PGF2α and PGF1α, 11-deoxy PGF1β exhibits vasodepressor and bronchodilator activities in guinea pigs at a dose of 500 μg/kg.
价 格：￥电议型 号：T36772产 地：中国大陆
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T3677111-deoxy Prostaglandin F1α；11-deoxy Prostaglandin F1α11-deoxy Prostaglandin F1α；11-deoxy Prostagland
11-deoxy PGF1α is a synthetic analog of PGF1α. In whole animal studies, a dose of 32 mg/kg inhibited gastric acid secretion by 35%. 11-deoxy PGF1α is also known to cause rat uterine contractions at a dose 0.3 times that of PGF1α. It also exhibits vasopressor and bronchoconstrictor activities at about half the potency of PGF2α in guinea pigs.
价 格：￥电议型 号：T36771产 地：中国大陆
