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T361658-iso-13,14-dihydro-15-keto Prostaglandin F2α;8-iso-13,14-dihydro-15-keto Prostaglandin F2α8-iso-13,
8-iso-13,14-dihydro-15-keto Prostaglandin F2α (8-iso-13,14-dihydro-15-keto PGF2α) is a metabolite of the isoprostane, 8-isoprostane (8-iso PGF2α), in rabbits, monkeys and humans. 8-iso PGF2α is a PG-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-isoprostane is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation. A similar pattern is observed when tritiated 8-isoprostane is infused into ra
价 格:¥电议型 号:T36165产 地:中国大陆
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T361648-iso Prostaglandin F3α;8-iso Prostaglandin F3α8-iso Prostaglandin F3α|||8-epi PGF3α;8-iso Prostagla
8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA. Little is known about the biological activity of 8-iso PGF3α. There is one report that it is inactive in a TP receptor mediated assay of human platelet shape change, where 8-iso PGF2α has an ED50 value of 1 uM. [1]
价 格:¥电议型 号:T36164产 地:中国大陆
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T361638-iso Prostaglandin F1β;8-iso Prostaglandin F1β8-iso Prostaglandin F1β;8-iso Prostaglandin F1β
8-iso PGF1β is a potential autoxidation product of DGLA. There are no published reports on its isolation from any biological source or on its biological activity.
价 格:¥电议型 号:T36163产 地:中国大陆
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T361628-iso Prostaglandin F1α;8-iso Prostaglandin F1α8-iso Prostaglandin F1α;8-iso Prostaglandin F1α
8-iso PGF1α is an isoprostane that was first identified in human semen. It is a member of the isoprostane family, which are eicosanoids of non-cyclooxygenase origin. 8-iso PGF1α is present along with its 19-hydroxy congener at 5-10 μg/ml of seminal plasma.
价 格:¥电议型 号:T36162产 地:中国大陆
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T361618-iso Prostaglandin E2 isopropyl ester;8-iso Prostaglandin E2 isopropyl ester8-iso Prostaglandin E2
8-iso PGE2 isopropyl ester is a more lipophilic form of the free acid, 8-iso PGE2. Prostaglandin esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid upon in vivo administration, making the esters useful prodrugs. In general, the C-1 esters of prostaglandins show greatly diminished agonist activity in vitro compared to the parent free acids.
价 格:¥电议型 号:T36161产 地:中国大陆
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T361608-iso Prostaglandin E2;8-iso Prostaglandin E28-iso Prostaglandin E2;8-iso Prostaglandin E2
8-iso PGE2 is one of several isoprostanes produced from arachidonic acid during lipid peroxidation. It is a potent renal vasoconstrictor in the rat. 8-iso PGE2 inhibits U-46619 or I-BOP-induced platelet aggregation with IC50 values of 0.5 and 5 μM, respectively. When infused into the renal artery of the rat at a concentration of 4 μg/kg/min, 8-iso PGE2 decreases the GFR and renal plasma flow by 80% without affecting blood pressure.
价 格:¥电议型 号:T36160产 地:中国大陆
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T361598-iso Prostaglandin E1;8-iso Prostaglandin E18-iso Prostaglandin E1;8-iso Prostaglandin E1
8-iso Prostaglandin E1 causes spasm in the pulmonary veins of dogs and also acts as a vasodilator.
价 格:¥电议型 号:T36159产 地:中国大陆
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T361588-iso Prostaglandin A2;8-iso Prostaglandin A28-iso Prostaglandin A2;8-iso Prostaglandin A2
8-iso Prostaglandin A2 is an isoprostane produced by the nonenzymatic oxidation of arachidonic acid.
价 格:¥电议型 号:T36158产 地:中国大陆
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T361578-iso Prostaglandin A1;8-iso Prostaglandin A18-iso Prostaglandin A1;8-iso Prostaglandin A1
8-iso Prostaglandin A1 (8-iso PGA1) is an isoprostane and a member in a large family of prostanoids of non-cyclooxygenase origin. It occurs as a common minor impurity in most commercial preparations of PGE1. The biological activity of 8-iso PGA1 has not been studied in depth or reported in the literature.
价 格:¥电议型 号:T36157产 地:中国大陆
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T3615615(S)-15-methyl Prostaglandin F2α methyl ester;15(S)-15-methyl Prostaglandin F2α methyl ester15(S)-1
15(S)-15-methyl Prostaglandin F2α methyl ester can be used in related research in the field of life sciences. Its product number is T36156 and CAS number is 35700-21-1.
价 格:¥电议型 号:T36156产 地:中国大陆
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T3615515(S)-15-methyl Prostaglandin F2α isopropyl ester;15(S)-15-methyl Prostaglandin F2α isopropyl ester1
15(S)-15-methyl Prostaglandin F2α (15(S)-15-methyl PGF2α) has been shown to have potent uterine stimulant and abortifacient properties when administered intramuscularly to induce labor. 15(S)-15-methyl PGF2α isopropyl ester is a lipophilic analog of 15(S)-15-methyl PGF2α methyl ester, which may be hydrolyzed in vivo to the fully active free acid.
价 格:¥电议型 号:T36155产 地:中国大陆
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T3615415(S)-15-methyl Prostaglandin E2;15(S)-15-methyl Prostaglandin E215(S)-15-methyl Prostaglandin E2;15
15(S)-15-methyl PGE2 is a potent, metabolically stable analog of PGE2. It is a potent gastric antisecretory and antiulcer compound. 15(S)-15-methyl PGE2 binds to human myometrium with twice the affinity of PGE2 and is ten times more potent than PGE1 in contracting uterine smooth muscle.
价 格:¥电议型 号:T36154产 地:中国大陆
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T3615315(S)-15-methyl Prostaglandin D2;15(S)-15-methyl Prostaglandin D215(S)-15-methyl Prostaglandin D2;15
15(S)-15-methyl Prostaglandin D2 (15(S)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2 . In contrast to PGD2, 15(S)-15-methyl PGD2 induces vasoconstriction and increases systemic blood pressure with much reduced inhibitory activity on ADP-induced platelet aggregation. It also exhibits strong antifertility activity in hamsters (200-fold more potent than PGD2).
价 格:¥电议型 号:T36153产 地:中国大陆
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T3614813,14-dihydro-15-keto Prostaglandin F1α;13,14-dihydro-15-keto Prostaglandin F1α13,14-dihydro-15-keto
13,14-dihydro-15-keto Prostaglandin F1α (13,14-dihydro-15-keto PGF1α) is a metabolite of PGF1α that has been reported in the rat stomach. The measurement of 13,14-dihydro-15-keto PGF1α can be used as a marker of the in vivo production of PGF1α.
价 格:¥电议型 号:T36148产 地:中国大陆
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T3614713,14-dihydro-15-keto Prostaglandin E1;13,14-dihydro-15-keto Prostaglandin E113,14-dihydro-15-keto P
13,14-dihydro-15-keto Prostaglandin E1 inhibits ADP-induced platelet aggregation in human isolated platelet-rich plasma (IC50=14.8 μg/mL) and is a PGE1 metabolite.
价 格:¥电议型 号:T36147产 地:中国大陆
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T3614613,14-dihydro Prostaglandin F2α;13,14-dihydro Prostaglandin F2α13,14-dihydro Prostaglandin F2α|||13,
13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain. It causes luteolysis in hamsters with a potency five times higher than PGF2α. The ED50 value for 13,14-dihydro PGF2α as a luteolytic agent in hamsters is 1.5 µg/100 g.[1]
价 格:¥电议型 号:T36146产 地:中国大陆
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T3614411β-Prostaglandin E2;11β-Prostaglandin E211β-PGE2|||11β-Prostaglandin E2;11β-PGE2|||11β-Prostaglandi
11β-PGE2 is the C-11 epimer of PGE2. It is a moderate inhibitor of PGE2 binding to rat hypothalamic membranes with a Ki value of 53 nM.[1] 11β-PGE2 also stimulates bone resorption in rats at concentrations of 10-8 to 10-6 M which is similar to PGE2.2 11β-PGE2 inhibits PGE2 binding to the prostaglandin transporter protein with a Ki of 56 nM.[3]
价 格:¥电议型 号:T36144产 地:中国大陆
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T360451a,1b-dihomo Prostaglandin E2;1a,1b-dihomo Prostaglandin E21a,1b-dihomo Prostaglandin E2;1a,1b-dihom
1a,1b-dihomo Prostaglandin E2 (PGE2) is a rare polyunsaturated fatty acid first identified in extracts of sheep vesicular gland microsomes, known to contain COX, incubated with adrenic acid . 1a,1b-dihomo PGE2 has also been identified in conditioned media of RAW 264.7 macrophages stimulated with endotoxin and arachidonic acid . This product is thought to be produced by elongation of AA to adrenic acid, which is then metabolized sequentially by COX and PGE synthase.
价 格:¥电议型 号:T36045产 地:中国大陆
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T3604116,16-dimethyl Prostaglandin A2;16,16-dimethyl Prostaglandin A216,16-dimethyl Prostaglandin A2;16,16
16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by >90% at a concentration of 4 μg/ml. Daily infusion of 10 μg of 16,16-dimethyl PGA2 methyl ester into mice infected with influenza A virus increased survival by 40%. Similar treatment of mice inoculated with erythroleukemia cells delayed tumor growth and increased survival time.
价 格:¥电议型 号:T36041产 地:中国大陆
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T3604016,16-dimethyl Prostaglandin A1;16,16-dimethyl Prostaglandin A116,16-dimethyl Prostaglandin A1;16,16
16,16-dimethyl Prostaglandin A1 是一种前列腺素类似物,可以抑制 Lewis 肺癌和 B 16无黑色素瘤细胞中的 DNA 合成 (DNA synthesis),以及抑制 HSV 和 HIV-1的病毒复制。
价 格:¥电议型 号:T36040产 地:中国大陆