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T37439C18 Globotriaosylceramide (d18:1/18:0)；C18 Globotriaosylceramide (d18:1/18:0)C18 Globotriaosylcerami
C18 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from lactosylceramide . It inhibits aggregation of human neutrophils induced by phorbol 12-myristate 13-acetate (PMA; 10008014) when used at a concentration of 1 μM. C18 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raji cells and THP-1 monocytes. It accumulates in the brain, heart, kidney, liver, lung, and spleen in a mouse model of Fabry disease, a lysosoma
价 格：￥电议型 号：T37439产 地：中国大陆
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T37438C17 Globotriaosylceramide (d18:1/17:0)；C17 Globotriaosylceramide (d18:1/17:0)C17 Globotriaosylcerami
C17 Globotriaosylceramide is a sphingolipid that has been used as an internal standard for the quantification of globotriaosylceramides in plasma and urine from patients with Fabry disease by GC-MS.
价 格：￥电议型 号：T37438产 地：中国大陆
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T37437C17 Ceramide (d18:1/17:0)；C17 Ceramide (d18:1/17:0)C17 Ceramide (d18:1/17:0)
C17 Ceramide is a synthetic ceramide that contains a non-natural C17:0 fatty acid acylated to sphingosine. It has been used as a marker of arylsulfatase A and sphingolipid activator B activity in patients undergoing enzyme replacement therapy for the genetic disease metachromatic leukodystrophy.
价 格：￥电议型 号：T37437产 地：中国大陆
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T37436C12-Ceramide；化合物 C12-CeramideN-Laurylsphingosine|||C12 Ceramide (d18:1/12:0)|||N-Lauroyl-D-erythro-s
C12-Ceramide (C12 Ceramide (d18:1/12:0)), a ceramide present in the protective membranes surrounding umbilical cord blood vessels in infants born to women with pre-eclampsia, can be used to assess the level of ASM activity in the plasma of patients with Niemann-Pick disease.
价 格：￥电议型 号：T37436产 地：中国大陆
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T37403O-desmethyl Brinzolamide (hydrochloride)；O-desmethyl Brinzolamide (hydrochloride)O-desmethyl Brinzol
O-desmethyl Brinzolamide is an active metabolite of the carbonic anhydrase (CA) inhibitor brinzolamide .1,2It inhibits CAII and CAIV (IC50s = 0.136 and 165 nM, respectively).1
价 格：￥电议型 号：T37403产 地：中国大陆
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T37291Lyso-Globotriaosylceramide (d18:1)；Lyso-Globotriaosylceramide (d18:1)Lyso-Globotriaosylceramide (d18
Lyso-globotriaosylceramide is a form of globotriaosylceramide that is lacking the fatty acyl group. It binds to Shiga toxin 1 (Stx1) in the presence of cholesterol and phosphatidylcholine but does not bind Stx2. It also reduces viability and aggregation of human neutrophils induced by phorbol 12-myristate 13-acetate when used at concentrations of 50 and 1 μM, respectively. Lyso-globotriaosylceramide accumulates in the brain, heart, kidney, liver, lung, and spleen in a mouse model of Fabry diseas
价 格：￥电议型 号：T37291产 地：中国大陆
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T37108Carboxyphosphamide；CarboxyphosphamideCarboxyphosphamide|||Carboxyphosphamide；Carboxyphosphamide|||Ca
Carboxyphosphamide is an inactive metabolite of the alkylating agent cyclophosphamide .1It is formed from cyclophosphamideviaoxidation of the intermediate metabolite aldophosphamide by aldehyde dehydrogenase.
价 格：￥电议型 号：T37108产 地：中国大陆
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T370461-Methyl-1,4-dihydronicotinamide；1-Methyl-1,4-dihydronicotinamide1-Methyl-1,4-dihydronicotinamide
1-Methyl-1,4-dihydronicotinamide is a nicotinamide derivative. Its product number is T37046 and CAS number is 17750-23-1.
价 格：￥电议型 号：T37046产 地：中国大陆
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T37009Oxychlororaphine；吩嗪-1-甲酰胺phenazine-1-carboxamide；吩嗪-1-甲酰胺|||phenazine-1-carboxamide
Oxychlororaphine (phenazine-1-carboxamide) inhibits strongly the growth of Streptomyces sp. 441.
价 格：￥电议型 号：T37009产 地：中国大陆
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T36979Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt)；Histone H3 (21-44)-GK-biotin amide (trifl
Histone H3 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.3 sequence and is biotinylated via a C-terminal GK linker. Unlike histone H3.1 and H3.2, the histone H3.3 variant contains a serine residue at position 31 that is phosphorylated during late prometaphase and metaphase of mitosis. Histone H3 (21-44) also contains lysine residues at positions 23, 27, and 36 that are subject to methylation and acetylation, all of whi
价 格：￥电议型 号：T36979产 地：中国大陆
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T36859C16 Globotriaosylceramide (d18:1/16:0)；C16 Globotriaosylceramide (d18:1/16:0)C16 Globotriaosylcerami
C16 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide . C16 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raji cells and THP-1 monocytes. It accumulates in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease. C16 globotriaosylceramide is also upregulated in plasma of patien
价 格：￥电议型 号：T36859产 地：中国大陆
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T36858C12 Galactosylceramide (d18:1/12:0)；C12 Galactosylceramide (d18:1/12:0)C12 Galactosylceramide (d18:1
C12 Galactosylceramide is a bioactive sphingolipid. It inhibits IL-4 production by 53.84% in EL4 T cells when used at a concentration of 10 μM. C12 Galactosylceramide reduces the growth of human papillomavirus type 16-associated tumors in mice and reduces tumor recurrence following surgical removal or chemotherapy. It also reduces natural killer T cell activity, delays the onset of proteinuria, and improves survival in a mouse model of systemic lupus.
价 格：￥电议型 号：T36858产 地：中国大陆
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T36812Linoleic Acid Amide；亚油酰胺9,12-Octadecadienamide|||Linoleamide|||Linoleic Acid Amide；9,12-Octadecadien
Linoleic Acid Amide (Linoleamide) is derived from linoleic acid and regulates Ca2+ flux by inhibiting the sarco/endoplasmic reticulum Ca2+-ATPase.
价 格：￥电议型 号：T36812产 地：中国大陆
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T36750Didesmethylrocaglamide；DidesmethylrocaglamideDidesmethylrocaglamide
Didesmethylrocaglamide, a Rocaglamide derivative, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor that exhibits strong growth-inhibitory effects, with an IC50 of 5 nM. It hinders several growth-promoting signaling pathways and triggers apoptosis in tumor cells, demonstrating antitumor activity[1].
价 格：￥电议型 号：T36750产 地：中国大陆
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T36671C2 Phytoceramide (t18:0/2:0)；C2 Phytoceramide (t18:0/2:0)C2 Phytoceramide (t18:0/2:0)
C2 Phytoceramide is a bioactive semisynthetic sphingolipid that inhibits formyl peptide-induced oxidant release (IC50 = 0.38 μM) in suspended polymorphonuclear cells. It increases COX-2 protein levels 15-fold through ERK signaling. It induces death of keratinocytes (20% viability) with an ED50 value of 30 μM, the same concentration at which 35% of cells in a TUNEL assay are apoptotic. C2 Phytoceramide also has antiproliferative effects in CHO cells, with greater than 80% cytotoxicity achieved at
价 格：￥电议型 号：T36671产 地：中国大陆
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T36638[Des-His1,Glu9]-Glucagon amide TFA；[Des-His1,Glu9]-Glucagon amide TFA[Des-His1,Glu9]-Glucagon amide
[Des-His1,Glu9]-Glucagon amide TFA is a potent peptide antagonist targeting the glucagon receptor, featuring a pA2 value of 7.2. It holds potential utility in diabetes pathogenesis research[1].
价 格：￥电议型 号：T36638产 地：中国大陆
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T36635[Ac-Tyr1,D-Phe2]GRF 1-29, amide (human)；[Ac-Tyr1,D-Phe2]GRF 1-29, amide (human)[Ac-Tyr1,D-Phe2]GRF 1
[Ac-Tyr1,D-Phe2]GRF 1-29, amide (human) is an analog of GRF and a vasoactive intestinal peptide (VIP) antagonist.
价 格：￥电议型 号：T36635产 地：中国大陆
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T36524IKK2-IN-4；IKK2抑制剂VI5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide|||IKK2 Inhibitor IV；5-Phenyl-2
IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.
价 格：￥电议型 号：T36524产 地：中国大陆
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T36449(S)-α-Methylbenzyl Ricinoleamide；(S)-α-Methylbenzyl Ricinoleamide(S)-α-Methylbenzyl Ricinoleamide
(S)-α-Methylbenzyl ricinoleamide is a fatty acid amide derived from ricinoleic acid and methyl benzylamine. It demonstrates potent growth inhibition of glioma (U251), breast (MCF-7), ovarian (NCI-ADR/RES and OVCAR-3), kidney (786-0), non-small cell lung (NCI-H460), and prostate (PC-3) cancer cells with a mean GI50 value of 6.9 μM.
价 格：￥电议型 号：T36449产 地：中国大陆
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T36426Eicosapentaenoyl 1-propanol-2-amide；Eicosapentaenoyl 1-propanol-2-amideEicosapentaenoyl 1-propanol-2
Monoacylglycerols (MAGs) of ω-3 polyunsaturated fatty acids have diverse physiological and health effects. In particular, MAGs containing docosahexaenoic acid or eicosapentaenoic acid have anti-proliferative properties against colon and lung cancer cell lines. Eicosapentaenoyl 1-propanol-2-amide is an EPA-containing MAG amide analog that inhibits the growth of human lung carcinoma A549 cells, producing 98.4% growth inhibition when applied at 3 μM. It is an analog of eicosapentaenoyl ethanolamide
价 格：￥电议型 号：T36426产 地：中国大陆
