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  • T36407Pyrrolidine Ricinoleamide；Pyrrolidine RicinoleamidePyrrolidine Ricinoleamide

    Ricinoleic acid is a naturally occurring 12-hydroxy fatty acid. It constitutes about 90% of the fatty acids in castor oil. Pyrrolidine Ricinoleamide is a derivative of the amide of ricinoleic acid that shows potent antiproliferative activity against an array of cancer cell lines, including human glioma U251 cells.

    价 格：￥电议型 号：T36407产 地：中国大陆

  • T36406Pyrrolidine Linoleamide；Pyrrolidine LinoleamidePyrrolidine Linoleamide

    Linoleic acid is an essential fatty acid and one of the most abundant polyunsaturated fatty acids in the western diet. Pyrrolidine Linoleamide is a derivative of the amide of linoleic acid that shows potent antiproliferative activity against an array of cancer cell lines, including human glioma U251 cells. It is greater than 4-fold more effective against cancer cells than non-cancer cells.

    价 格：￥电议型 号：T36406产 地：中国大陆

  • T36403Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate；Preterramide CMethyl 3,4,5-trimethoxy-

    Preterramide C is a fungal metabolite that has been found inA. terreus.1It is active againstS. aureus(MIC = 52.4 μM) but notE. aerogenes,P. aeruginosa, orC. albicans(MICs = >100 μM for all).2Preterramide C inhibits the growth of L5178Y mouse lymphoma cells with an IC50value of 0.1 μg/ml.3It also inhibits nitric oxide (NO) production induced by LPS in RAW 264.7 cells (IC50= 5.48 μM).

    价 格：￥电议型 号：T36403产 地：中国大陆

  • T36380GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)；GLP-1 (1-36) amide (human, rat) (trifluoroac

    GLP-1 amide is a peptide hormone cleaved from proglucagon in the pancreas.

    价 格：￥电议型 号：T36380产 地：中国大陆

  • T36377Somatorelin (1-44) amide (human) (trifluoroacetate salt)；Somatorelin (1-44) amide (human) (trifluoro

    Somatorelin (1-44) amide is a synthetic peptide that corresponds to the full 44-amino acid sequence of growth hormone-releasing hormone (GHRH), a hormone that stimulates the production of growth hormone from the pituitary gland and is involved in the regulation of cell proliferation and differentiation.1,2Somatorelin induces growth hormone release similarly to GHRHin vitroandin vivo.1

    价 格：￥电议型 号：T36377产 地：中国大陆

  • T36328Termitomycamide BTermitomycamide BTermitomycamide B

    Endoplasmic reticulum (ER) stress, caused by accumulation of misfolded proteins and a disruption of calcium homeostasis, has been linked to several neuronal diseases including, Parkinson´s, Alzheimer´s, and prion diseases. A screen for protective activity against ER stress-dependent cell death identified termitomycamides, extracts from the fruiting bodies of T. titanicus, a notably large edible mushroom that is cultivated symbiotically in the nests of termites Termitomycamide B is a

    价 格：￥电议型 号：T36328产 地：中国大陆

  • T36324C8 L-threo Ceramide (d18:1/8:0)；C8 L-threo Ceramide (d18:1/8:0)C8 L-threo Ceramide (d18:1/8:0)；C8 L-

    C8 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It is cytotoxic to U937 cells (IC50 = 10 μM) and, like C8 D-threo ceramide , induces nuclear DNA fragmentation 5- to 6-fold more potently than C8 L-erythro ceramide . C8 D-threo Ceramide also enhances V. cholerae cytolysin pore formation in liposome lipid membranes, as measured by calcein release, with a 50% release dose (RD50) value of ~30 μg/ml.

    价 格：￥电议型 号：T36324产 地：中国大陆

  • T36323C8 Galactosylceramide (d18:1/8:0)；C8 Galactosylceramide (d18:1/8:0)C8 Galactosylceramide (d18:1/8:0)

    C8 Galactosylceramide is a synthetic C8 short-chain derivative of known membrane microdomain-forming sphingolipids. It increases the amount delivered and toxicity of doxorubicin in cancerous but not non-cancerous cells when incorporated into the nanoliposomal membrane of nanoliposomal-doxorubicin. C8 Galactosylceramide induces proliferation and cytokine production by splenocytes in vitro at concentrations ranging from 100-1,000 ng/ml but has no effect on natural killer T cell production in vivo.

    价 格：￥电议型 号：T36323产 地：中国大陆

  • T36322C8 D-threo Ceramide (d18:1/8:0)；C8 D-threo Ceramide (d18:1/8:0)C8 D-threo Ceramide (d18:1/8:0)；C8 D-

    C8 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It is cytotoxic to U937 cells (IC50 = 17 μM) and induces nuclear DNA fragmentation 5- to 6-fold more potently than C8 ceramide . C8 D-threo Ceramide is a substrate for E. coli diacylglycerol kinase. It activates ceramide-activated protein kinase (CAPK) in U937 cells. C8 D-threo Ceramide also enhances V. cholerae cytolysin pore formation in liposome lipid membranes, as measured by calcein r

    价 格：￥电议型 号：T36322产 地：中国大陆

  • T36321C6 Urea CeramideC6 Urea CeramideC6 Urea Ceramide|||C-6 Urea Ceramide

    C6 urea ceramide is an inhibitor of neutral ceramidase.1 It increases total ceramide levels in wild-type mouse embryonic fibroblasts (MEFs) and in HT-29 colon cancer cells but not in MEFs lacking neutral ceramidase. It inhibits proliferation of, and induces apoptosis and autophagy in HT-29, but not non-cancerous RIE-1, cells when used at concentrations of 5 and 10 μM. C6 urea ceramide decreases total β-catenin, increases phosphorylated β-catenin, and induces colocalization of β-catenin with the

    价 格：￥电议型 号：T36321产 地：中国大陆

  • T36320C6 L-threo Ceramide (d18:1/6:0)；C6 L-threo Ceramide (d18:1/6:0)C6 L-threo Ceramide (d18:1/6:0)；C6 L-

    C6 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 L-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 L-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 L-threo Ceramide enhances IL-4 production induced by phorbol 12-myristate 13-acetate in EL4 T cells when used at a concentration of 10 μM.

    价 格：￥电议型 号：T36320产 地：中国大陆

  • T36319C6 L-erythro Ceramide (d18:1/6:0)；C6 L-erythro Ceramide (d18:1/6:0)C6 L-erythro Ceramide (d18:1/6:0)

    C6 L-erythro Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It is metabolized by ceramide glucosyltransferase to form C6 L-erythro glucosylceramide. C6 L-erythro Ceramide is cytotoxic to U937 cells (IC50 = 18 μM).

    价 格：￥电议型 号：T36319产 地：中国大陆

  • T36286Protease-Activated Receptor-3 (PAR-3) (1-6), human；PAR-3 (1-6) amide (human)Protease-Activated Recep

    TFRGAP-amide, human PAR-3-derived tethered ligand sequence which does not activate PAR-3 but rather activates PAR-1 and PAR-2, either in Jurkat or in other PAR-expressing cells.

    价 格：￥电议型 号：T36286产 地：中国大陆

  • T36285VH 032 amide-PEG1-acid；VH 032 amide-PEG1-acidVH 032 amide-PEG1-acid；VH 032 amide-PEG1-acid

    Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG1 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

    价 格：￥电议型 号：T36285产 地：中国大陆

  • T36284(S,R,S)-AHPC-C8-NH2 dihydrochloride；VH 032 amide-alkylC8-amineVH 032 amide-alkylC8-amine；VH 032 amid

    Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 11 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

    价 格：￥电议型 号：T36284产 地：中国大陆

  • T36283VH 032 amide-alkylC8-acid；VH 032 amide-alkylC8-acidVH 032 amide-alkylC8-acid；VH 032 amide-alkylC8-ac

    Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus alkylC8 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

    价 格：￥电议型 号：T36283产 地：中国大陆

  • T36282VH 032 amide-alkylC7-amineVH 032 amide-alkylC7-amineVH 032 amide-alkylC7-amine

    Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

    价 格：￥电议型 号：T36282产 地：中国大陆

  • T36281VH 032 amide-alkylC5-amine；VH 032 amide-alkylC5-amineVH 032 amide-alkylC5-amine；VH 032 amide-alkylC5

    Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 13 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

    价 格：￥电议型 号：T36281产 地：中国大陆

  • T36280VH 032 amide-alkylC4-acid；VH 032 amide-alkylC4-acidVH 032 amide-alkylC4-acid；VH 032 amide-alkylC4-ac

    Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus alkylC4 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 5 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

    价 格：￥电议型 号：T36280产 地：中国大陆

  • T36279VH 032 amide-alkylC3-amine；VH 032 amide-alkylC3-amineVH 032 amide-alkylC3-amine；VH 032 amide-alkylC3

    Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl C3 linker and terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

    价 格：￥电议型 号：T36279产 地：中国大陆

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