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T35907Paraherquamide A；Paraherquamide AParaherquamide A
Paraherquamide A is a mycotoxin anthelmintic originally isolated from P. paraherquei. It binds to acetylcholine receptors (IC50 = 0.5 nM for head homogenates of M. domestica) and acts as an antagonist. Paraherquamide A is toxic to C. elegans (LD50 = 2.5 μg/ml) and effective against T. colubriformis infection in gerbils when used at doses ranging from 0.39 to 200 mg/kg. It is toxic to mice (LD50 = 14.9 mg/kg).
价 格：￥电议型 号：T35907产 地：中国大陆
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T35906Padanamide A；Padanamide APadanamide A
Padanamide A is a bacterial metabolite originally isolated from a marine Streptomyces species. It is active against five strains of P. falciparum (EC50s = 160-340 nM), is not cytotoxic to HEK293 or HepG2 human cell lines, but is cytotoxic to Jurkat T lymphocytes with an IC50 value of approximately 60 μg/ml.
价 格：￥电议型 号：T35906产 地：中国大陆
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T35873C19 Ceramide (d18:1/19:0)；C19 Ceramide (d18:1/19:0)C19 Ceramide (d18:1/19:0)；C19 Ceramide (d18:1/19:
C19 Ceramide is a naturally occurring ceramide that has been found in J. juncea extracts as well as rat brain and mouse heart.[1],[2],[3] It is elevated in adult and decreased in juvenile whole rat brain extracts by 114 and 37%, respectively, following chronic ethanol exposure.[2] C19 Ceramide is also increased in mouse hearts following administration of angiotensin II.[3]
价 格：￥电议型 号：T35873产 地：中国大陆
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T358404-Amino-6-chloro-1,3-benzenedisulfonamide；4-Amino-6-chloro-1,3-benzenedisulfonamide4-Amino-6-chloro-
4-Amino-6-chloro-1,3-benzenedisulfonamide is a carbonic anhydrase inhibitor.1 Formulations containing this compound are diuretics.2 4-Amino-6-chloro-1,3-benzenedisulfonamide is detected as a hydrolysis product of chlorothiazide in the urine.2 Diuretics, including chlorothiazide, have been abused as performance-enhancing drugs and masking agents in sports doping.3
价 格：￥电议型 号：T35840产 地：中国大陆
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T35810C24 dihydro Ceramide (d18:0/24:0)；C24 dihydro Ceramide (d18:0/24:0)Cer(d18:0/24:0)；Cer(d18:0/24:0)
C24 dihydro Ceramide is a sphingolipid that has been found in the stratum corneum of human skin.[1] It is found in higher concentrations in female sebum compared to male sebum.[2] C24 dihydro Ceramide levels positively correlate with cytotoxicity in CCRF-CEM, MOLT-4, COG-LL-317h, and COG-LL-332h T cell acute lymphoblastic leukemia (ALL) cell lines.[4] Levels of C24 dihydro ceramide are increased by 149.49-fold in dihydroceramide desaturase 1 (DEGS1) knockdown UM-SCC-22A human head and neck squam
价 格：￥电议型 号：T35810产 地：中国大陆
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T35808C18:1 Ceramide (d18:1/18:1(9Z))；C18:1 Ceramide (d18:1/18:1(9Z))Cer(d18:1/18:1(9Z))；Cer(d18:1/18:1(9Z
C18:1 Ceramide is a naturally occurring ceramide.[1][2][3] Levels of C18:1 ceramide are elevated in overweight and insulin-resistant mice and cattle.[1][2] C18:1 Ceramide is also increased in the plasma and ovarian tissue of patients with advanced ovarian cancer. [3]
价 格：￥电议型 号：T35808产 地：中国大陆
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T35807C18 dihydro Ceramide (d18:0/18:0)；C18 dihydro Ceramide (d18:0/18:0)C18 dihydro Ceramide (d18:0/18:0)
C18 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C18 ceramide that lacks the 4,5-trans double bond. [1] Increased C18 dihydroceramide lipid levels lead to increased triacylglycerol storage and autophagosome accumulation as well as upregulation of the fibrosis markers α-SMA and FGF2 in Chang and LX-2 liver cells. C18 dihydro Ceramide is elevated in the plasma of pre-diabetics up to 9 years prior to the onset of type 2 diabetes. [2] It is also elevated in
价 格：￥电议型 号：T35807产 地：中国大陆
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T35806N-Stearoylsphingosine；N-硬脂酰神经鞘氨醇C(18:0)/C(18:1)|||Cer(d18:1/18:0)|||C18 Ceramide (d18:1/18:0)|||C18
N-Stearoylsphingosine (Cer(d18:1/18:0)) is an amide compound widely found in eukaryotic organisms that enhances protein phosphatase 2A (PP2A) activity by interfering with the binding of PP2A to PP2A inhibitor 2, leading to dephosphorylation of Akt.N-Stearoylsphingosine is used in prostate cancer research.
价 格：￥电议型 号：T35806产 地：中国大陆
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T35804C16 Lactosylceramide (d18:1/16:0)；C16 Lactosylceramide (d18:1/16:0)C16 Lactosylceramide (d18:1/16:0)
C16 Lactosylceramide is an endogenous bioactive sphingolipid. It forms membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs), suggesting a role in cell signaling. Plasma levels of C16 lactosylceramide are elevated in insulin-resistant cattle. C16 Lactosylceramide is also upregulated in a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder.
价 格：￥电议型 号：T35804产 地：中国大陆
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T35803C14 Ceramide (d18:1/14:0)；十四酰鞘氨醇Cer(d18:1/14:0)|||N-Myristoyl-D-sphingosine；Cer(d18:1/14:0)|||N-Myri
C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson´s research.
价 格：￥电议型 号：T35803产 地：中国大陆
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T35796Lactosylceramides (bovine buttermilk)；乳糖神经酰胺LacCer (bovine buttermilk)；LacCer (bovine buttermilk)
Lactosylceramides (bovine buttermilk) (LacCer (bovine buttermilk)) are ceramides isolated from bovine buttermilk that inhibit cell proliferation and are used to study tumors and liver lesions.
价 格：￥电议型 号：T35796产 地：中国大陆
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T35713N-desethyl Brinzolamide (oxalate)；N-desethyl Brinzolamide (oxalate)N-desethyl Brinzolamide (oxalate)
N-desethyl Brinzolamide is an active metabolite of the carbonic anhydrase (CA) inhibitor brinzolamide .1It inhibits CAII and CAIV activities (IC50s = 1.28 and 128 nM, respectively).
价 格：￥电议型 号：T35713产 地：中国大陆
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T35693N-(2-Azidoethyl)betulonamide；N-(2-Azidoethyl)betulonamideN-(2-Azidoethyl)betulonamide
N-(2-Azidoethyl)betulonamide is a pentacyclic triterpenoid, a derivative of betulonic acid , and an intermediate in the synthesis of betulonic acid derivatives within vitrocancer cell cytotoxicity.1
价 格：￥电议型 号：T35693产 地：中国大陆
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T356802-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide；2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbo
2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is an antimicrobial agent.1It is active against the Gram-negative bacteriaE. coli,P. aeruginosa, andS. marcescens(MICs = 64, 100, and 70 μg/ml, respectively), the Gram-positive bacteriaS. aureus,M. luteus, andB. cereus(MICs = 130, 100, and 50 μg/ml, respectively), and the fungiC. albicans,G. candidum,T. rubrum,F. oxysporum,A. flavus, andS. brevicaulis(MICs = 69-120 μg/ml). 2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is also a prec
价 格：￥电议型 号：T35680产 地：中国大陆
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T356782,3-Indolobetulinic glycine amide；2,3-Indolobetulinic glycine amide2,3-Indolobetulinic glycine amide
2,3-Indolobetulinic glycine amide is a pentacyclic triterpene and derivative of betulinic acid .1It has been used in the synthesis of betulinic acid derivatives with anticancer activity.
价 格：￥电议型 号：T35678产 地：中国大陆
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T356454-oxo Cyclophosphamide；4-oxo Cyclophosphamide4-oxo Cyclophosphamide
4-oxo Cyclophosphamide is an inactive metabolite of the alkylating agent cyclophosphamide .1,2It is formed from cyclophosphamide through a 4-hydroxycyclophosphamide intermediate by aldehyde dehydrogenases.2
价 格：￥电议型 号：T35645产 地：中国大陆
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T356434-hydroperoxy Cyclophosphamide；4-hydroperoxy Cyclophosphamide4-hydroperoxy Cyclophosphamide|||4-OOH-
4-hydroperoxy Cyclophosphamide (4-OOH-CY) is the active metabolite form of the prodrug Cyclophosphamide. 4-OOH-CY crosslinks DNA and induces T cell apoptosis independent of death receptor activation, but activates mitochondrial death pathways through production of reactive oxygen species (ROS).[1] Formulations containing the prodrug Cyclophosphamide are used to treat lymphomas and autoimmune disorders.[2],[3]
价 格：￥电议型 号：T35643产 地：中国大陆
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T3562Valrocemide；丙戊塞胺TV1901|||N-Valproylglycinamide；TV1901|||N-丙戊酰基甘氨酰胺|||N-Valproylglycinamide|||丙戊塞胺
Valrocemide (TV1901), also known as TV-1901, is an antiepileptic drug (AED). Valrocemide has a broad spectrum of anticonvulsant activity and promising potential as a new AED. Valrocemide is an anticonvulsant agent under development by Teva and Acorda as a potential therapeutic for the treatment of epilepsy.
价 格：￥电议型 号：T3562产 地：中国大陆
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T355184-methoxythio Benzamide；4-methoxythio Benzamide4-methoxythio Benzamide
4-methoxythio Benzamide is a synthetic intermediate useful for pharmaceutical synthesis. Thiobenzamides, including 4-methoxythio benzamide, are potent hepatotoxins in vivo.
价 格：￥电议型 号：T35518产 地：中国大陆
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T355163-methoxythio Benzamide；3-methoxythio Benzamide3-methoxythio Benzamide
3-methoxythio Benzamide is a synthetic intermediate useful for pharmaceutical synthesis. Thiobenzamides, including 3-methoxythio benzamide, are potent hepatotoxins in vivo.
价 格：￥电议型 号：T35516产 地：中国大陆
