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T10706CCI-006CCI-006
CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells. It inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response in a subset of MLL-r leukem
价 格:¥电议型 号:T10706产 地:美洲
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T10707CCK-B Receptor Antagonist 2CCK-B Receptor Antagonist 2
CCK-B Receptor Antagonist 2 is a potent and orally active antagonist of Gastrin/CCK-B (IC50: 0.43 nM). It also inhibits gastrin/CCK-A activity (IC50: 1.82 μM).
价 格:¥电议型 号:T10707产 地:美洲
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T11070DO34 analogDO34 analog
DO34 analog is a triazole DAGL(α) inhibitor extracted from patent WO2017096315 A1, compound 100.
价 格:¥电议型 号:T11070产 地:美洲
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T11070LDO34DO34
DO34 is a highly potent and centrally active inhibitor of diacylglycerol lipase (IC50: 6 nM for DAGLα conversion of SAG to 2-AG).
价 格:¥电议型 号:T11070L产 地:美洲
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T12664(Rac)-BRD0705(Rac)-BRD0705
(Rac)-BRD0705 is a less active racemate of BRD0705. BRD0705 is a potent, paralog selective and orally active inhibitor of GSK3α (IC50 of 66 nM and a Kd of 4.8 μM). BRD0705 displays increased selectivity for GSK3α (8-fold) versus GSK3β (IC50 of 515 nM).
价 格:¥电议型 号:T12664产 地:美洲
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T15465HC-070HC-070
HC-070 is a TRPC4/TRPC5 antagonist (IC50s of 9.3 nM and 46 nM for hTRPC5 and hTRPC4 in cells, respectively).
价 格:¥电议型 号:T15465产 地:美洲
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T16070MF63MF63
MF63 is a selective mPGES-1 inhibitor (IC50: 0.9 nM and 1.3 nM for pig mPGES-1 and human mPGES-1 enzyme, respectively).
价 格:¥电议型 号:T16070产 地:美洲
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T19070TMB monosulfateTMB monosulfate,BM blue monosulfate,Sure Blue TMB monosulfate
TMB monosulfate (BM blue monosulfate) is a chromogenic substrate used in staining procedures in immunohistochemistry and a visualizing reagent used in ELISA.
价 格:¥电议型 号:T19070产 地:美洲
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T1927CCT007093CCT007093
CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).
价 格:¥电议型 号:T1927产 地:美洲
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T2070CEP-32496CEP-32496,CEP32496,CEP 32496
CEP-32496 is a highly potent inhibitor of BRAF.
价 格:¥电议型 号:T2070产 地:美洲
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T2487CerdulatinibCerdulatinib,PRT2070,PRT062070
Cerdulatinib is an novel oral dual Syk/JAK inhibitor.
价 格:¥电议型 号:T2487产 地:美洲
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T4641LMI 070LMI 070,NVS-SM1,Branaplam
LMI070 (NVS-SM1) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.
价 格:¥电议型 号:T4641产 地:美洲
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T50705,7-Dihydroxy-4-phenylcoumarin5,7-Dihydroxy-4-phenylcoumarin
5,7-dihydroxy-4-phenyl coumarin is found in the plant Passiflora serratodigitata with the antibacterial activity.
价 格:¥电议型 号:T5070产 地:美洲
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T6104Cerdulatinib hydrochlorideCerdulatinib hydrochloride,Cerdulatinib,PRT062070
Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM.
价 格:¥电议型 号:T6104产 地:美洲
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T6275Obatoclax MesylateObatoclax Mesylate,GX15-070,Obatoclax
Obatoclax is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3.
价 格:¥电议型 号:T6275产 地:美洲
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T6420BMS-707035BMS-707035,BMS707035,BMS 707035
BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.
价 格:¥电议型 号:T6420产 地:美洲
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T8720PRX-07034 hydrochloride;化合物PRX-07034PRX-07034;PRX-07034
PRX-07034 hydrochloride is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and potently decreases food intake and body weight in rodents. PRX-07034 hydrochloride is both a potent (Ki = 4-8 nM) and highly selective 5-HT(6) receptor antagonist (≥100-fold selectivity for the 5-HT(6) receptor compared to 68 other GPCRs, ion channels, and transporters, except D(3) (Ki = 71 nM) and 5-HT(1B) (Ki = 260 nM) receptors.
价 格:¥电议型 号:T8720产 地:中国大陆
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T83070Antifungal agent 63;化合物 Antifungal agent 63Antifungal agent 63
Compound 3i (Antifungal agent 63) is a fungicidal agent displaying potent activity against Fusarium oxysporum f.sp. cucumerinum and has applications in antiviral and fungicidal research [1].
价 格:¥电议型 号:T83070产 地:中国大陆
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T82070Ingol 7,8,12-triacetate 3-(4-methoxyphenyl)acetate;化合物 Ingol 7,8,12-triacetate 3-(4-methoxyphenyl)ac
Ingol 7,8,12-triacetate 3-(4-methoxyphenyl)acetate, a complex ingol diterpene derived from the latex of Euphorbia officinarum, features multiple acetate functional groups [1].
价 格:¥电议型 号:T82070产 地:中国大陆
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T81500PF-07059013;化合物 PF-07059013PF-07059013
PF-07059013, an orally active and potent noncovalent modulator of sickled hemoglobin (HbS), specifically binds to Hb with nanomolar affinity and demonstrates substantial partitioning into red blood cells (RBCs), making it useful for sickle cell disease (SCD) research [1][2].
价 格:¥电议型 号:T81500产 地:中国大陆